Results 71 to 80 of about 33,844 (200)

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

Tapetal Expression of BnaC.MAGL8.a Causes Male Sterility in Arabidopsis

open access: yesFrontiers in Plant Science, 2019
Monoacylglycerol lipase (MAGL) hydrolyzes monoacylglycerol, producing free fatty acid and glycerol. Although this enzyme has been shown to play important roles in mammal, its potential function in plants remains poorly understood. In a survey of the MAGL
Jie Gao   +11 more
doaj   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Ontogeny of microsomal activities of triacylglycerol synthesis in guinea pig liver.

open access: yesJournal of Lipid Research, 1987
Because the onset of triacylglycerol-rich lipoprotein synthesis occurs in guinea pig liver during fetal life, we investigated the microsomal enzyme activities of triacylglycerol synthesis in fetal and postnatal guinea pig liver.
R A Coleman, E B Haynes, C D Coats
doaj   +1 more source

A Super‐Resolution Approach for Astrocyte‐Specific Molecular Imaging Reveals the Nanoscale Distribution of Monoacylglycerol Lipase, the Metabolic Node Between Endocannabinoid and Prostaglandin Signaling

open access: yesGlia, Volume 74, Issue 9, September 2026.
Dual‐color STORM resolves the precise architecture and protein distributions within hippocampal astrocytes at the nanoscale. Identification of a sparse but specific MAGL pool in CA1 astrocytic processes. Astrocytic MAGL is not synapse‐associated, suggesting a synapse‐independent role.
Miklós Zöldi, István Katona
wiley   +1 more source

Understanding the Molecular Processes of Obesity and the Anti‐Obesity Properties of Bioactive Substances Found in Tea

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
ABSTRACT Obesity, a severe worldwide health concern, is characterized as an excessive deposit of fat in the human body. It has various ramifications that endanger human health and increase the financial expense. Obesity raises the risk of several illnesses, notably cardiovascular disease, NALFD, and diabetes, and has been associated with shorter ...
Sakhawat Riaz   +6 more
wiley   +1 more source

Cyclic Treatment With WIN 18,446, a Potential Male Contraceptive, is as Effective as Continuous Treatment for Suppression of Spermatogenesis in Mice

open access: yesAndrology, Volume 14, Issue 6, Page 1472-1478, September 2026.
ABSTRACT Background Retinoic acid plays a critical role in spermatogenesis during both spermatogonial differentiation and spermiation. Mice lacking enzymes that synthesize retinoic acid, Aldh1a1/1a2, in the testes are infertile. WIN 18,446 reversibly inhibits spermatogenesis by inhibiting ALDH1A1/1A2 and is a promising approach to male contraception ...
Jisun Paik   +3 more
wiley   +1 more source

Biobased Polyurethane Films Based on Andiroba (Carapa guianensis) and Buriti (Mauritia flexuosa) Oil Polyols

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 30, August 10, 2026.
Polyurethane films were prepared from andiroba (Carapa guianensis) and buriti (Mauritia flexuosa) oil‐derived polyols, emphasizing their potential as bio‐based materials. UV–Vis analysis indicates the retention of carotenoid‐related chromophoric features within the polymer matrix.
João A. P. da Silva   +5 more
wiley   +1 more source

Design‐Driven Production of Soybean Oil‐Based Structured Fats as Potential Substitutes for Palm‐Based Fats

open access: yesJournal of the American Oil Chemists' Society, Volume 103, Issue 8, Page 873-886, August 2026.
ABSTRACT This study examined whether enzymatic modification of soybean oil (SBO) can be tailored to produce trans‐free fats with physicochemical properties comparable to palm olein, stearin, or palm‐mid fractions (PMFs). US‐grown SBO was modified by lipase‐catalyzed acidolysis using palmitic acid at linearly interpolated substrate molar ratios (C16:0 ...
Ityotagher P. Aondoakaa   +2 more
wiley   +1 more source

Of Mice and MAGL (Monoacylglycerol Lipase)

open access: yesThe FASEB Journal, 2011
About 18.8 million American adults suffer depressive disorders that may occur with anxiety and substance abuse. Tetrahydrocannabinol (THC), a compound in marijuana, is a cannabinoid chemical that binds to and activates cannabinoid receptors (CB1) in the pre‐synaptic cell membrane as part of neuron‐to‐neuron transmission in the ...
S. Bach   +28 more
openaire   +1 more source

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