Results 41 to 50 of about 37,127 (223)

Lipid Oxidation in Dispersive Systems with Monoacylglycerols

Czech Journal of Food Sciences, 2009
Model fat blends with a monoacylglycerol emulsifier with different acyl chain (C10, C12, C14, C16, C18, C18:1, C20, C22) were prepared and stored under oxygen atmosphere 8 weeks at temperature 20°C.
V. Spěváčková, I. Hrádková, M. Ebrtová, V. Filip, M. Tesařová   +4 more
doaj   +1 more source

The monoacylglycerol acyltransferase pathway contributes to triacylglycerol synthesis in HepG2 cells

Scientific Reports, 2022
The monoacylglycerol acyltransferase (MGAT) pathway has a well-established role in the small intestine where it facilitates the absorption of dietary fat.
Pamela J. McFie, Apurv Patel, Scot J. Stone   +2 more
doaj   +1 more source

Monoacylglycerol lipase (MAGL) Inhibitors

, 2021
The present invention relates to compounds of formula (I) useful as inhibitors, in particular as reversible non-covalent inhibitors, of the enzyme monoacylglycerol lipase (MAGL). The present invention also relates to the therapeutic use of such compounds,
Poli G, Tuccinardi T, Macchia M, Minutolo F, Giordano A, Bononi G, Scalabrini D, Granchi C, Rizzolio F   +8 more
core  

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration [PDF]

, 2023
Background & Aims: Liver regeneration is a repair process in which metabolic reprogramming of parenchymal and inflammatory cells plays a major role. Monoacylglycerol lipase (MAGL) is an ubiquitous enzyme at the crossroad between lipid metabolism and ...
Cadoux, Mathilde, Morgane Mabire, Hervé Guillou, Al-Sayegh, Rola, Caër, Charles, Charles Caër, Catherine Postic, Valérie Paradis, JingHong Wan, Mathilde Cadoux, Aida Habib, Pierre de la Grange, Wan, Jinghong, Postic, Catherine, de la Grange, Pierre, Manon Allaire, Hélène Gilgenkrantz, Adel Hammoutene, Hammoutene, Adel, Maude Le Gall, Al Sayegh, Rola, Gilgenkrantz, Hélène, Sophie Lotersztajn, Allaire, Manon, Guillou, Hervé, Paradis, Valérie, Lotersztajn, Sophie, Habib, Aida, Matthieu Siebert, Mabire, Morgane, Rola Al Sayegh, Le Gall, Maude, Siebert, Matthieu   +32 more
core   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Inhibitors of monoacylglycerol lipase as novel analgesics [PDF]

British Journal of Pharmacology, 2007
2‐Arachidonoylglycerol (2‐AG) is an endogenous cannabinoid (endocannabinoid) lipid whose functions remain poorly understood. Guindon and colleagues report the novel finding that exogenous application of 2‐AG induces peripheral antinociceptive effects that are mediated, at least in part, by actions at peripheral cannabinoid CB2 receptors.
openaire   +2 more sources

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Sensing of triacylglycerol in the gut:different mechanisms for fatty acids and 2-monoacylglycerol

, 2015
KEY POINTS: Digestion is required for intestinal sensing of triacylglycerol in this behavioural model. The hydrolysis products of triacylglycerol, fatty acids and 2-monoacylglycerol, regulate feeding via separate mechanisms.
Jacobsen, Anne Katrine, Hansen, Harald S, Rehfeld, Jens F, Holst, Jens Juul, de Araujo, Ivan E, Kleberg, Karen, Ferreira, Jozelia G, Windeløv, Johanne Agerlin   +7 more
core   +1 more source

Revisiting Securidaca longipedunculata Seed Oil: Applying NMR and Mass Spectroscopy to Confirm the Presence of 2‐Acetyl‐1,3‐Diacyl–sn‐Glycerols and Conjugated Hydroxydienoic Fatty Acids

Journal of the American Oil Chemists' Society, EarlyView.
The manuscript confirms and expands on previous reports concerning the presence of unusual conjugated hydroxydienoic fatty acids and acetyl‐TAG in the seed oil of Securidaca longipedunculata. The location of acetate only at sn‐2 of TAG was conclusively shown by high resolution NMR and hydroxy seed fatty acids are characterized.
Mark A. Smith, Jianfeng Zhu, Jin‐Yue Sun   +2 more
wiley   +1 more source

Catalytic properties of MGAT3, a putative triacylgycerol synthases⃞

Journal of Lipid Research, 2007
Acyl-coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) is a member of the MGAT family of enzymes that catalyze the synthesis of diacylglycerol (DAG) from monoacylglycerol (MAG), a committed step in dietary fat absorption.
Jingsong Cao, Long Cheng, Yuguang Shi
doaj   +1 more source