Results 31 to 40 of about 33,581 (195)

Monoacylglycerol lipase: stopping surplus at the synapse

The Journal of Physiology, 2011
Endocannabinoids (eCBs) are a family of molecules derived from membrane phospholipids which exert biological effects through specific receptors. In the brain, eCBs are perhaps the most ubiquitous and potent neurotransmitters known to act in a retrograde manner.
Jaclyn I, Wamsteeker, Jaideep S, Bains
openaire   +3 more sources

A novel pathway for lipid biosynthesis: the direct acylation of glycerol

Journal of Lipid Research, 2001
The acylation of glycerol-3-phosphate by acyl-CoA is regarded as the first committed step for the synthesis of the lipoidal moiety in glycerolipids. The direct acylation of glycerol in mammalian tissues has not been demonstrated.
Douglas P. Lee, Andrew S. Deonarine, Martin Kienetz, Quansheng Zhu, Monika Skrzypczak, Monroe Chan, Patrick C. Choy   +6 more
doaj   +1 more source

Phospholipase A2 relieves phosphatidylcholine inhibition of micellar cholesterol absorption and transport by human intestinal cell line Caco-21

Journal of Lipid Research, 1998
Cholesterol absorption from bile acid micelles is suppressed by phosphatidylcholine (PC) in the micelles. The effects of micellar phospholipid composition on absorption, metabolism, and secretion of lipids were examined in Caco-2 cells incubated with ...
Reynold Homan, Katherine L. Hamelehle
doaj   +1 more source

Lipid second messengers and related enzymes in vertebrate rod outer segments

Journal of Lipid Research, 2010
Rod outer segments (ROSs) are specialized light-sensitive organelles in vertebrate photoreceptor cells. Lipids in ROS are of considerable importance, not only in providing an adequate environment for efficient phototransduction, but also in originating ...
Norma M. Giusto, Susana J. Pasquaré, Gabriela A. Salvador, Mónica G. Ilincheta de Boschero   +3 more
doaj   +1 more source

Lipid Alterations in Chronic Nonspecific Low Back Pain in the Chinese Population: A Metabolomic and Lipidomic Study

Bioengineering
Chronic nonspecific low back pain (cNLBP) accounts for approximately 90% of low back pain cases, affecting 65–80% of the population and significantly impacting life quality and productivity.
Wen Tang, Hong-Jiang Wang, Su-Ying Luo, Si-Yun Zhang, Hao Xie, Hua-Qing Chen, Chu-Huai Wang, Zhou Zhang   +7 more
doaj   +1 more source

Lipid Oxidation in Dispersive Systems with Monoacylglycerols

Czech Journal of Food Sciences, 2009
Model fat blends with a monoacylglycerol emulsifier with different acyl chain (C10, C12, C14, C16, C18, C18:1, C20, C22) were prepared and stored under oxygen atmosphere 8 weeks at temperature 20°C.
V. Spěváčková, I. Hrádková, M. Ebrtová, V. Filip, M. Tesařová   +4 more
doaj   +1 more source

The monoacylglycerol acyltransferase pathway contributes to triacylglycerol synthesis in HepG2 cells

Scientific Reports, 2022
The monoacylglycerol acyltransferase (MGAT) pathway has a well-established role in the small intestine where it facilitates the absorption of dietary fat.
Pamela J. McFie, Apurv Patel, Scot J. Stone   +2 more
doaj   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Excipient Emulsion–Based Delivery Systems for Enhancing Carotenoid Bioavailability: Advances in Formulation and Gastrointestinal Fate

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Excipient emulsion systems improve carotenoid solubilization, protect against degradation, and enhance gastrointestinal absorption through optimized formulation and digestion behavior. ABSTRACT Carotenoids are bioactive compounds that contribute to human health through antioxidant, provitamin A, and disease‐preventive effects.
Tugce Ceyhan, Elifsu Nemli, Esra Capanoglu, Merve Tomas   +3 more
wiley   +1 more source

Catalytic properties of MGAT3, a putative triacylgycerol synthases⃞

Journal of Lipid Research, 2007
Acyl-coenzyme A:monoacylglycerol acyltransferase 3 (MGAT3) is a member of the MGAT family of enzymes that catalyze the synthesis of diacylglycerol (DAG) from monoacylglycerol (MAG), a committed step in dietary fat absorption.
Jingsong Cao, Long Cheng, Yuguang Shi
doaj   +1 more source