Results 11 to 20 of about 33,581 (195)
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature
PLoS ONE, 2022 Chronic inflammation and blood–brain barrier dysfunction are key pathological hallmarks of neurological disorders such as multiple sclerosis, Alzheimer’s disease and Parkinson’s disease. Major drivers of these pathologies include pro-inflammatory stimuli
Alicia M. Kemble +10 more
doaj +2 more sources
Grasas y Aceites, 2015 The production of monoacylglycerol rich in polyunsaturated fatty acids (PUFA) via enzymatic glycerolysis of sardine oil in a homogeneous system was evaluated. Reactions were conducted in two different tert-alcohols.
Á. G. Solaesa +4 more
doaj +1 more source
Advances in Food Science, Sustainable Agriculture, and Agroindustrial Engineering, 2022 This research aimed to evaluate the effect of flow rate and processing time on the synthesis of high mono- and diacylglycerol (MDAG) from palm stearin-olein blend using high shear continuous stirred tank reactor (HS-CSTR).
Elma Sulistiya +2 more
doaj +1 more source
A first attempt into the production of acylglycerol mixtures from Echium oil
Frontiers in Bioengineering and Biotechnology, 2016 Enzymatic glycerolysis of Echium oil (Echium plantagineum) has been carried out in the presence of four commercial lipases. Different pretreatment of the reaction mixture, such as high pressure homogenization and addition of food grade monoolein as an ...
Luis eVázquez +4 more
doaj +1 more source
Molecules, 2022 A simple and practical synthesis of 2-arachidonoyl glycerol (2-AG), an endogenous agonist for cannabinoid receptors, based on a two-step enzymatic process and a chemical coupling, was achieved with a good yield and negligible amount of the isomerization ...
Roberta Ottria +3 more
doaj +1 more source
Journal of Lipid Research, 1998 The binding of monoacylglycerides of long-chain fatty acids to human serum albumin has been examined using monooleoylglycerol as the ligand. Binding was investigated using changes in tryptophan fluorescence and also the displacement of a variety of well ...
Alfred E.A. Thumser +2 more
doaj +1 more source
Inhibition of Aspergillus niger DMF 0801 by monoacylglycerols prepared from coconut oil
Czech Journal of Food Sciences, 2002 The objectives of the present study were to test the antifungal properties (inhibition of radial growth, inhibition of the mould spore germination) of lauroylglycerol and mixtures of monoacylglycerols synthesised from coconut oil (MIX-I and MIX-II ...
Z. Řiháková +4 more
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Beilstein Journal of Organic Chemistry, 2023 A new antibacterial 3-monoacyl-sn-glycerol, nostochopcerol (1), was isolated from a cultured algal mass of the edible cyanobacterium Nostochopsis lobatus MAC0804NAN. The structure of compound 1 was established by the analysis of NMR and MS data while its
Naoya Oku +4 more
doaj +1 more source