Results 11 to 20 of about 37,127 (223)
α/β-Hydrolase Domain-6-Accessible Monoacylglycerol Controls Glucose-Stimulated Insulin Secretion [PDF]
, 2014 International audienceGlucose metabolism in pancreatic β cells stimulates insulin granule exocytosis, and this process requires generation of a lipid signal.
Iglesias, Jose +14 more
core +7 more sources
Discrepancy in Reported and Observed Monoacylglycerol Lipase Inhibition of Aryl Formyl Piperidine Containing Potent and Highly Selective Monoacylglycerol Lipase Inhibitor. [PDF]
ChemMedChemA reported potent and selective reversible MAGL inhibitor fails to reproduce its claimed potency in two established in vitro assays, even when the previously reported substrate is used, while eight related analogs are likewise inactive. The findings highlight substantial assay‐dependent behavior and the need for careful validation before such compounds
Savinainen JR +3 more
europepmc +2 more sources
Jurnal Teknologi dan Industri Pangan, 2010 Antibacterial mechanism of mixture between metabolites Lb.plantarum klik and monoacylglycerol coconut oil was found through analysis of the MIC levels. The level of 1 and 2 MIC can increase the leakages of the gram positif bacterial sell (L.monocytogenes
Asriani . +3 more
doaj +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Antibacterial electrospun membrane prepared from poly (vinylidene fluoride)-co-hexafluoropropylene with lauric acid monoacylglycerol [PDF]
, 2021 The aim of this study was to prepare an antibacterial nanofibrous membrane using electrospinning technique. The nanofibrous membranes were spun from polymer solution of poly(vinylidne fluoride)-cohexafluoropropylene (PVDF-co-HFP) dissolved in N,N ...
Zelenková, Jana +5 more
core +1 more source
Grasas y Aceites, 2015 The production of monoacylglycerol rich in polyunsaturated fatty acids (PUFA) via enzymatic glycerolysis of sardine oil in a homogeneous system was evaluated. Reactions were conducted in two different tert-alcohols.
Á. G. Solaesa +4 more
doaj +1 more source
A first attempt into the production of acylglycerol mixtures from Echium oil
Frontiers in Bioengineering and Biotechnology, 2016 Enzymatic glycerolysis of Echium oil (Echium plantagineum) has been carried out in the presence of four commercial lipases. Different pretreatment of the reaction mixture, such as high pressure homogenization and addition of food grade monoolein as an ...
Luis eVázquez +4 more
doaj +1 more source
Advances in Food Science, Sustainable Agriculture, and Agroindustrial Engineering, 2022 This research aimed to evaluate the effect of flow rate and processing time on the synthesis of high mono- and diacylglycerol (MDAG) from palm stearin-olein blend using high shear continuous stirred tank reactor (HS-CSTR).
Elma Sulistiya +2 more
doaj +1 more source
Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]
, 2012 BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Geisslinger, Gerd +27 more
core +2 more sources