Results 1 to 10 of about 33,844 (200)
Marine Drugs, 2014 A monoacylglycerol (1) and a 1:1 mixture of two monogalactosyl diacylglycerols (MGDGs) (2 and 3) were isolated from the brown seaweed Fucus spiralis Linnaeus.
Patricia Valentão +2 more
exaly +3 more sources
Monoacylglycerol lipase – a target for drug development? [PDF]
British Journal of Pharmacology, 2012 The endocannabinoid (eCB) system is involved in processes as diverse as control of appetite, perception of pain and the limitation of cancer cell growth and invasion. The enzymes responsible for eCB breakdown are attractive pharmacological targets, and fatty acid amide hydrolase inhibitors, which potentiate the levels of the eCB anandamide, are now ...
Christopher Fowler, C J Fowler
exaly +3 more sources
Monoacylglycerol Lipase Regulates Fever Response. [PDF]
PLoS ONE, 2015 Cyclooxygenase inhibitors such as ibuprofen have been used for decades to control fever through reducing the levels of the pyrogenic lipid transmitter prostaglandin E2 (PGE2).
Manuel Sanchez-Alavez +7 more
doaj +4 more sources
α/β-Hydrolase Domain-Containing 6 (ABHD6)— A Multifunctional Lipid Hydrolase
Metabolites, 2022 α/β-hydrolase domain-containing 6 (ABHD6) belongs to the α/β-hydrolase fold superfamily and was originally discovered in a functional proteomic approach designed to discover monoacylglycerol (MAG) hydrolases in the mouse brain degrading the ...
Lisa-Maria Pusch +4 more
doaj +1 more source
Investigation of lipolytic activity of the red king crab hepatopancreas homogenate by NMR spectroscopy [PDF]
PeerJ, 2022 The digestive gland of craboids (hepatopancreas) is rich in a huge number of various enzymes (collagenases, nucleases, hyaluronidases, proteases), which are well studied at the moment. However, little is known about crustacean lipases.
Maria Timchenko +4 more
doaj +2 more sources
Conversion of Pulse Protein Foam-Templated Oleogels into Oleofoams for Improved Baking Application
Foods, 2022 The food industry has long been searching for an efficient replacement for saturated-fatty-acid-rich fats for baking applications. Although oleogels have been considered a potential alternative for saturated and trans fats, their success in food ...
Athira Mohanan +4 more
doaj +1 more source
Distinct 1-monoacylglycerol and 2-monoacylglycerol kinase activities of diacylglycerol kinase isozymes [PDF]
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2016 Diacylglycerol kinase (DGK) consists of ten isozymes and is involved in a wide variety of patho-physiological events. However, the enzymological properties of DGKs have not been fully understood. In this study, we performed a comprehensive analysis on the 1-monoacylglycerol kinase (MGK) and 2-MGK activities of ten DGK isozymes. We revealed that type I (
Sato, Yuriko +5 more
openaire +2 more sources
Molecular Plant-Microbe Interactions, 2022 Arbuscular mycorrhizal fungi (AMF) colonize roots, where they provide nutrients in exchange for sugars and lipids. Because AMF lack genes for cytosolic fatty acid de novo synthase (FAS), they depend on host-derived fatty acids.
Mathias Brands, Peter Dörmann
doaj +1 more source
Assay of Monoacylglycerol Lipase Activity [PDF]
, 2016 Monoacylglycerol lipase (MGL) is a serine hydrolase involved in the biological deactivation of the endocannabinoid 2-arachidonoyl-sn-glycerol (2-AG). 2-AG is one of the main endogenous lipid agonists for cannabinoid receptors in the brain and elsewhere in the body.
Jung, Kwang-Mook, Piomelli, Daniele
openaire +5 more sources
A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature
PLoS ONE, 2022 Chronic inflammation and blood–brain barrier dysfunction are key pathological hallmarks of neurological disorders such as multiple sclerosis, Alzheimer’s disease and Parkinson’s disease. Major drivers of these pathologies include pro-inflammatory stimuli
Alicia M. Kemble +10 more
doaj +2 more sources