Results 171 to 180 of about 97,734 (211)
Is It Possible to Bypass the Block in Cerebral Glucose Uptake Following TBI with Exogenous Lactate? [PDF]
MetabolitesBrooks GA.
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SLC16A13 Promotes Malignant Progression in Glioma via Metabolic Reprogramming and Disruption of Monocarboxylate Homeostasis. [PDF]
Neurochem ResYang S, Liu Y, Hui X, Yang A.
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Monocarboxylate Transporters in the Central Nervous System: Distribution, Regulation and Function
Journal of Neurochemistry, 2005 Monocarboxylate transporters (MCTs) are proton-linked membrane carriers involved in the transport of monocarboxylates such as lactate, pyruvate, as well as ketone bodies.
Luc Pellerin, Karin Pierre
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Neuroscience, 2000 Recent evidence suggests that lactate could be a preferential energy substrate transferred from astrocytes to neurons. This would imply the presence of specific transporters for lactate on both cell types.
Luc Pellerin +2 more
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Thyroid Hormone Transport by Monocarboxylate Transporters
Best Practice & Research Clinical Endocrinology & Metabolism, 2007Thyroid hormone (TH) is essential for the normal development and metabolism of different tissues. TH action and metabolism take place intracellularly, which requires cellular uptake via transporters. Several transporter families have been identified, of which the monocarboxylate transporter (MCT) family deserves special attention.
Visser Edward +2 more
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Cancer Management and Research, 2023 Tian Liu,1,* Shangcong Han,2,* Yu Yao,1 Guiming Zhang1 1Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China; 2Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao ...
Shangcong Han, Guiming Zhang, Tian Liu
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Monocarboxylate Transport Matters
New England Journal of Medicine, 2014The liver makes ketone bodies (3-hydroxybutyrate, acetoacetate, and acetone, the breakdown product of acetoacetate) from fat when intracellular glucose is in short supply — for example, in starvation or unregulated diabetes. The generated 3-hydroxybutyrate and acetoacetate serve as alternative energy sources for the cells.
Linda H, Bergersen, Tore, Eid
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Role of monocarboxylate transporters and glucose transporters in prostate cancer
Urologia Journal, 2022Objectives: Currently, research of new diagnostic approaches to detect clinically significant prostate cancer is relevant because of the importance of early detection of aggressive forms of the disease, often challenging, even when using modern diagnostic tools.
Stanislav Vovdenko +4 more
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Comprehensive Physiology, 2013
Abstract Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported across both the plasma membrane and mitochondrial inner membrane. A family of five proton‐linked MonoCarboxylate Transporters (MCTs) is involved in the former and the mitochondrial ...
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Abstract Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported across both the plasma membrane and mitochondrial inner membrane. A family of five proton‐linked MonoCarboxylate Transporters (MCTs) is involved in the former and the mitochondrial ...
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Monocarboxylate transport in erythrocytes
The Journal of Membrane Biology, 1982Transport of anions across the red blood cell membrane has been studied intensively in recent years under the impact of the successful identification and molecular characterization of the transport protein mediating chloride/bicarbonate exchange. The features of this electrically silent exchange process which is mediated by a 95-K Dalton intrinsic ...
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