Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells. [PDF]
, 1989 Raphael Hirsch +4 more
openalex +1 more source
Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab
Advanced Healthcare Materials, EarlyView.Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone +17 more
wiley +1 more source
Monoclonal antibody OKT-9 recognizes the receptor for transferrin on human acute lymphocytic leukemia cells. [PDF]
, 1981 James W. Goding, G F Burns
openalex +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Characterization of the binding properties and retrograde axonal transport of a monoclonal antibody directed against the rat nerve growth factor receptor. [PDF]
, 1985 Megumi Taniuchi, E. Marshall Johnson
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Plasma oxidation following polydopamine deposition can significantly reduce the surface hydrophobicity of polyurethane‐siloxanes without impacting surface roughness, thereby increasing fibroblast viability, adhesion, and extracellular matrix production and secretion.
Sophie Armstrong +5 more
wiley +1 more source
Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells
Advanced Healthcare Materials, EarlyView.Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd +8 more
wiley +1 more source
Monoclonal antibodies to Chlamydia psittaci: Characteristics and antigenic analysis.
, 1988 Chiyoko Seki +3 more
openalex +2 more sources
A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11b/CD18 (Mac-1). [PDF]
, 1988 Dario C. Altieri, T S Edgington
openalex +1 more source