Results 201 to 210 of about 1,044,682 (307)

Electrochemically Engineered PEDOT:PSS/MXene Composite Electrode for the Label‐Free Procalcitonin Detection

Advanced Materials Interfaces, EarlyView.
Procalcitonin is a key biomarker for bacterial infections, but conventional detection methods are often time‐consuming. Here, we present an electrochemical sensor based on highly conductive Ti3C2Tx MXene combined with PEDOT:PSS, enabling direct antibody immobilization, while a bovine serum albumin coating provides antifouling protection.
Angelika Banaś, Roman Turczyn, Maciej Krzywiecki, Izabela Matuła, Sara Shakibania, Katarzyna Krukiewicz, Deivasigamani Ranjith Kumar   +6 more
wiley   +1 more source

Microfluidic Hydroporation Platform for Effective Allogeneic CAR‐T Cell Production and Subsequent Functional Cytotoxicity Analysis

Advanced Materials Technologies, EarlyView.
The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon, Sein Kim, Hyun‐Young Kim, Duck Cho, Sungsu Park, Seohyun Kim, Aram J. Chung   +6 more
wiley   +1 more source

Quality Gaps in Online Media Coverage of Antiamyloid Monoclonal Antibodies for Alzheimer Disease.

JAMA Netw Open
Macedo AC, de Lima AG, Miaw ISL, Bizzi IH, Balbino JMV, Therriault J, Zimmer ER, Ghezzi P, Rosa-Neto P.   +8 more
europepmc   +1 more source

Human monoclonal antibodies that target clade 2.3.4.4b H5N1 hemagglutinin. [PDF]

Nat Commun
Alzua GP, León AN, Yellin T, Bhavsar D, Loganathan M, Bushfield K, Brouwer PJM, Rodriguez AJ, Jeevan T, Webby R, Marizzi C, Han J, Ward AB, Duty JA, Krammer F.   +14 more
europepmc   +1 more source

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

Advanced Materials Technologies, EarlyView.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee, Sehyeon Kim, Dasom Kong, Hye‐min Park, Hyun‐Ji Park, Jinsik Kim   +5 more
wiley   +1 more source

Clinical Qualification of Subcutaneous Injection Devices for Monoclonal Antibodies. [PDF]

BioDrugs
Bittner B, Munoz J, Frank S, Dolton M, Ravanello R, Dembowski M, Clement A, Richter WF.   +7 more
europepmc   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Selective clearance of monoclonal antibodies via the mannose receptor is dependent on glycan pairing. [PDF]

Sci Rep
Baumeister J, Meudt M, Wei W, Ebert S, Rosenau F, Mizaikoff B, Blech M, Chen LZ, Higel F.   +8 more
europepmc   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

Advanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng, Torben A.B. van der Boon, Savannah Amy Haupt, Adam Jones, Yanjing Ji, Theo G. Van Kooten, Patrick van Rijn   +6 more
wiley   +1 more source

CD47 monoclonal antibodies differ in their capacity to induce immune response. [PDF]

Eur J Microbiol Immunol (Bp)
Cham LB, Albaloshi J, Alnakhli A, Farid E, Hamdan TA, Adomati T, Barbouche MR.   +6 more
europepmc   +1 more source