Results 221 to 230 of about 715,660 (339)

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source

Evidence-Based Recommendations on the Use of Immunotherapies and Monoclonal Antibodies in the Treatment of Male Reproductive Cancers. [PDF]

Curr Oncol
Khalid F, Bodla ZH, Gaddameedi SR, Macasaet R, Yagnik K, Niaz Z, Fish PN, Du D, Shah S.   +8 more
europepmc   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Second-generation anti-amyloid monoclonal antibodies for Alzheimer's disease: current landscape and future perspectives. [PDF]

Transl Neurodegener
Kim BH, Kim S, Nam Y, Park YH, Shin SM, Moon M.   +5 more
europepmc   +1 more source

Monoclonal Antibody Therapy [PDF]

AAOHN Journal, 1987
openaire   +3 more sources

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Current use and development of monoclonal antibodies for the treatment of systemic lupus erythematosus: a review. [PDF]

Antib Ther
Blagov A, Orekhov N, Churov A, Starodubtseva I, Beloyartsev D, Kovyanova T, Sukhorukov V, Orekhov A.   +7 more
europepmc   +1 more source

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

Advanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He, Jiapei Cai, Xufeng Xie, Xinyu Zhang, Linkai Qu, Jiuxi Liu, Yongguo Cao   +6 more
wiley   +1 more source

Monoclonal antibodies: From magic bullet to precision weapon. [PDF]

Mol Biomed
Aboul-Ella H, Gohar A, Ali AA, Ismail LM, Mahmoud AEE, Elkhatib WF, Aboul-Ella H.   +6 more
europepmc   +1 more source

A monoclonal antibody (Po66) directed against human lung squamous cell carcinoma immunolocalization of tumour xenografts in nude mice

, 1987
L. Dazord, Dominique Bourel, Anne F. Martin, Rozenn Lecorre, P. Bourguet, J. Bohy, Jean-Claude Saccavini, Philippe Delaval, M Louvet, Louis Toujas   +9 more
openalex   +1 more source