Results 241 to 250 of about 715,660 (339)

Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii. [PDF]

Biotechnol Bioeng
Yang Y, Dalvie NC, Brady JR, Naranjo CA, Lorgeree T, Rodriguez-Aponte SA, Johnston RS, Tracey MK, Elenberger CM, Lee E, Tié M, Love KR, Love JC.   +12 more
europepmc   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

Advanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan, Renwang Sheng, Weikun Li, Yinghua Tao, Zonghao Liu, Ning Yang, Syeda Safia Hashmi, Feiling Feng, Fangzhou Liu, Liqin Ge   +9 more
wiley   +1 more source

Monoclonal Antibodies in Metastatic Gastro-Esophageal Cancers: An Overview of the Latest Therapeutic Advances. [PDF]

Int J Mol Sci
Kalofonou F, Kalofonou M, Dimitrakopoulos FI, Kalofonos H.   +3 more
europepmc   +1 more source

Reprogramming the Tumor Immune Microenvironment with ICAM‐1‐Targeted Antibody‒Drug Conjugates and B7‐H3‐CD3 Bispecific Antibodies

Advanced Science, EarlyView.
Reprogramming the tumor immune microenvironment is crucial for transforming immune “cold” tumors into “hot” inflammatory tumors. The investigation reveals that the combination of ICAM‐1‐Dxd with B7‐H3‐CD3 bispecific antibodies not only demonstrates significant inhibitory effects on tumor growth and metastasis but also plays a vital role in ...
Shoubing Zhou, Mengyu Hong, Dan Zhao, Wenyu Li, Xiaolong Yuan, Yinghong Wang, Hualong Li, Yang Yang, Tengchuan Jin, Jing Pan   +9 more
wiley   +1 more source

Humanized anti-CD11d monoclonal antibodies suitable for basic research and therapeutic applications. [PDF]

Antib Ther
Blythe EN, Barreira C, Fink C, Brown A, Weaver LC, Dekaban GA.   +5 more
europepmc   +1 more source

Monoclonal antibodies to the nuclear matrix of chick embryonal erythrocytes.

, 1984
Yoshihiro Tsutsui, Shinsuke Saga, Munemitsu Hoshino   +2 more
openalex   +2 more sources

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

Advanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu, Meicen Wu, Qingyang Lyu, Chang Yang, Ni Fan, Kang Chen, Weiping Wang   +6 more
wiley   +1 more source

An application of fluorescein-conjugated monoclonal antibodies to the diagnosis of Chlamydia trachomatis infection in children.

, 1985
Kei Numazaki, Shunzo Chiba, T Moroboshi, Nobutada Tachi, Koki Aoki, Tooru Nakao   +5 more
openalex   +2 more sources

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

The Development and Characterization of Two Monoclonal Antibodies Against the Conjugates and Derivatives of the Immunometabolite Itaconate. [PDF]

ACS Omega
Switala L, Di L, Colantonio S, Lakshman B, Caceres TW, Reading JJ, Garcia-Buntley SS, Maiseyeu A.   +7 more
europepmc   +1 more source