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Monoclonal antibodies are established in clinical practice for the treatment of cancer, and autoimmune and infectious diseases. The first generation of antibodies has been dominated by classical IgG antibodies, however, in the last decade, the field has advanced, and, nowadays, a large proportion of antibodies in development have been engineered.
openaire +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Exploring parental awareness and willingness to use monoclonal antibodies for respiratory syncytial virus prevention. [PDF]
Abu-Farha R +5 more
europepmc +1 more source
High‐Concentration Antibody Formulation via Solvent‐Based Dehydration
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng +3 more
wiley +1 more source
Development of novel anti-CDH1/E-cadherin monoclonal antibodies for versatile applications. [PDF]
Ubukata R, Suzuki H, Kaneko MK, Kato Y.
europepmc +1 more source
Pharmacokinetics of Monoclonal Antibodies Throughout Pregnancy: A Systematic Literature Review [PDF]
Jip van Gendt +8 more
openalex +1 more source
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu +11 more
wiley +1 more source
Plant-produced monoclonal antibodies recognize the native circumsporozoite protein on <i>Plasmodium falciparum</i> sporozoites. [PDF]
Thiganta K +5 more
europepmc +1 more source

