Results 51 to 60 of about 13,966 (231)

Circulating serum microRNAs as novel diagnostic and prognostic biomarkers for multiple myeloma and monoclonal gammopathy of undetermined significance

Haematologica, 2014
Multiple myeloma still remains incurable in the majority of cases prompting a further search for new and better prognostic markers. Emerging evidence has suggested that circulating microRNAs can serve as minimally invasive biomarkers for multiple myeloma
Lenka Kubiczkova, Fedor Kryukov, Ondrej Slaby, Elena Dementyeva, Jiri Jarkovsky, Jana Nekvindova, Lenka Radova, Henrieta Greslikova, Petr Kuglik, Eva Vetesnikova, Ludek Pour, Zdenek Adam, Sabina Sevcikova, Roman Hajek   +13 more
doaj   +1 more source

Low Dose Pegylated Interferon Alpha as a First‐Line Treatment for Necrobiotic Xanthogranuloma

JEADV Clinical Practice, EarlyView.
ABSTRACT Necrobiotic xanthogranuloma (NXG) is a rare, progressive granulomatous disorder frequently associated with monoclonal gammopathy, particularly monoclonal gammopathy of undetermined significance (MGUS). It typically presents with indurated to ulcerative yellowish plaques or nodules, often with ocular involvement.
Ishana Dixit, Charmaine Vanessa S. Chamberlin, Pablo Fernandez‐Peñas   +2 more
wiley   +1 more source

PARAPROTEINEMIC POLYNEUROPATHY ASSOCIATED WITH MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE: СLINICAL CASE DESCRIPTION AND LITERATURE REVIEW

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Monoclonal gammopathy of undetermined significance represents a number of conditions, the development of which is based on functional impairment of B-lymphocytes, which results in permanent pathological secretion of a single clone of immunoglobulins or ...
A. A. Yakovlev, E. S. Tarabanova, A. G. Smochilin, R. A. Gapeshin, M. V. Yakovleva   +4 more
doaj   +1 more source

A case of monoclonal gammopathy of undetermined significance and minimal change disease complicated by bilateral pulmonary emboli

SAGE Open Medical Case Reports, 2022
Nephrotic syndrome and monoclonal gammopathy of undetermined significance are thought to be associated with venous thromboembolism. However, the association is thought to be weak and is often ignored by clinicians.
Thanuja Neerukonda, Alexandra Witt, Arsen Tan, Bilal Farooqi, Yasna Chaudhary, Christina Kovacs, Luis Silva   +6 more
doaj   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru, Nesrine Brahimi, Haleh Zabihi, Cathryn Sibbald, Kyle Seigel, Delaram Shojaei, Eric McMullen, Afsaneh Alavi, Lily Archaempong, Aaron M. Drucker, Adam Weizman, Kenneth Croitoru, Robert Inman, Vincent Piguet   +13 more
wiley   +1 more source

A case of immunotactoid glomerulopathy with false-negative IgG staining

BMC Nephrology, 2018
Background Immunotactoid glomerulopathy (ITG) is a rare glomerulonephritis characterized by microtubular deposits. Immunofluorescence findings are necessary to differentiate ITG from other proliferative glomerular diseases.
Shuma Hirashio, Takahiro Arima, Ayaka Satoh, Kouichi Mandai, Shigeo Hara, Takao Masaki   +5 more
doaj   +1 more source

Practical Approach to Managing SCIg Treatment in Patients With Chronic Inflammatory Demyelinating Polyneuropathy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Guidelines for the management of chronic inflammatory demyelinating polyneuropathy (CIDP) recommend corticosteroids, intravenous immunoglobulin (IVIg), or plasma exchange for first‐line therapies and subcutaneous immunoglobulin (SCIg) as a maintenance option.
Tuan Vu, Claudia Guerra, Niraja Suresh, Sami Khella, Jamie Morrell, Michael Pulley, Nan Jiang, Khema Sharma, Tulio Bertorini, Nivedita Jerath, Amanda Peltier   +10 more
wiley   +1 more source

Secondary monoclonal gammopathy of unknown significance with isotype switching after CAR T-cell therapy for multiple myeloma: A case report

Current Problems in Cancer: Case Reports
The incidence of secondary monoclonal gammopathy of undetermined significance is limited in patients with multiple myeloma post chimeric antigen receptor T-cell therapy.
Nilesh M. Kalariya, Hans C. Lee, Muzaffar H. Qazilbash, Krina K. Patel   +3 more
doaj   +1 more source

Monoclonal gammopathy of renal significance: From bench to bedside

Journal of Indira Gandhi Institute of Medical Sciences
Monoclonal gammopathy of renal significance (MGRS) is a unique subset of plasma cell dyscrasias where monoclonal immunoglobulins (IG) cause kidney damage.
Megha Saigal, Pulkit Khosla, Arghya Chakraborty, Amresh Krishna   +3 more
doaj   +1 more source

C3 glomerulonephritis associated with monoclonal gammopathy of renal significance: case report

BMC Nephrology, 2018
Background Morbidity associated with monoclonal gammopathy of renal significance is high due to the severe renal lesions and the associated systemic alterations.
Juana Alonso-Titos, Lara Perea-Ortega, Eugenia Sola, Alvaro Torres-Rueda, Myriam León, Remedios Toledo, Ana D. Duarte, Teresa Vazquez, Maria Dolores Martinez-Esteban, Alicia Bailen, Pedro Ruiz-Esteban, Domingo Hernandez   +11 more
doaj   +1 more source