Results 1 to 10 of about 400,128 (308)

Susceptibility to Infections During Acute Liver Injury Depends on Transient Disruption of Liver Macrophage Niche

Frontiers in Immunology, 2022
Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact ...
Mateus Eustáquio Lopes, Brenda Naemi Nakagaki, Matheus Silvério Mattos, Gabriel Henrique Campolina-Silva, Gabriel Henrique Campolina-Silva, Raquel de Oliveira Meira, Pierre Henrique de Menezes Paixão, André Gustavo Oliveira, Lucas D. Faustino, Ricardo Gonçalves, Gustavo Batista Menezes   +10 more
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Platelet Activity and Its Correlation with Inflammation and Cell Count Readings in Chronic Heart Failure Patients with Reduced Ejection Fraction

Medicina, 2021
Background and objectives: There has been an increasing interest in the role of inflammation in thrombosis complications in chronic heart failure (HF) patients.
Aušra Mongirdienė, Jolanta Laukaitienė, Vilius Skipskis, Lolita Kuršvietienė, Julius Liobikas   +4 more
doaj   +1 more source

AFM negatively regulates the infiltration of monocytes to mediate sepsis-associated acute kidney injury

Frontiers in Immunology, 2023
BackgroundSepsis is organ dysfunction due to the host’s deleterious response to infection, and the kidneys are one of the organs damaged in common sepsis.
Caiyun Guo, Youling Fan, Youling Fan, Jiurong Cheng, Yingdong Deng, Xiangsheng Zhang, Yanna Chen, Huan Jing, Wenjun Li, Pei Liu, Jiaqi Xie, Wenjun Ning, Hongtao Chen, Jun Zhou   +13 more
doaj   +1 more source

Mass cytometry and single-cell RNA sequencing reveal immune cell characteristics of active and inactive phases of Crohn’s disease

Frontiers in Medicine, 2023
ObjectivesFor Crohn’s disease (CD), the alternation of the active phase and inactive phase may be related to humoral immunity and cellular immunity. This study aims to understand the characteristics of immune cells in patients with active CD (CDa) and ...
Wenjia Lin, Shiying Liu, Zhuojian Huang, Haiwen Li, Tianyu Lu, Yongxin Luo, Jiamin Zhong, Zewen Xu, Yu Liu, Yanwu Li, Yanwu Li, Peiwu Li, Qian Xu, Jiazhong Cai, Jiazhong Cai, Huibiao Li, Xin-lin Chen   +16 more
doaj   +1 more source

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells [PDF]

Journal of Immunology Research, 2016
Blood monocytes are precursors of dendritic cells, macrophages, and osteoclasts. They are a heterogeneous cell population with differences in size, phenotype, and function. Although monocytes maintain several tissue-specific populations of immune cells in homeostasis, their contribution to populations of dendritic cells, macrophages, and osteoclasts is
Sara Sprangers, Teun J. de Vries, Vincent Everts   +2 more
openaire   +6 more sources

Macrophage-Secreted CSF1 Transmits a Calorie Restriction-Induced Self-Renewal Signal to Mammary Epithelial Stem Cells

Cells, 2022
Calorie restriction enhances stem cell self-renewal in various tissues, including the mammary gland. We hypothesized that similar to their intestinal counterparts, mammary epithelial stem cells are insulated from sensing changes in energy supply ...
Anna Kosenko, Tomer Meir Salame, Gilgi Friedlander, Itamar Barash   +3 more
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Distinct effector functions mediated by Fc regions of bovine IgG subclasses and their interaction with Fc gamma receptors

Frontiers in Immunology, 2023
Cattle possess three IgG subclasses. However, the key immune functions, including complement and NK cell activation, and enhancement of phagocytosis, are not fully described for bovine IgG1, 2 and 3.
Alistair Noble, Basudev Paudyal, John C. Schwartz, William Mwangi, Danish Munir, Elma Tchilian, John A. Hammond, Simon P. Graham   +7 more
doaj   +1 more source

Increased Monocyte Production of IL-6 after Toll-like Receptor Activation in Children with Autism Spectrum Disorder (ASD) Is Associated with Repetitive and Restricted Behaviors

Brain Sciences, 2022
The prevalence of autism spectrum disorder (ASD) has starkly increased, instigating research into risk factors for ASD. This research has identified immune risk factors for ASD, along with evidence of immune dysfunction and excess inflammation frequently
Heather K. Hughes, Charity E. Onore, Milo Careaga, Sally J. Rogers, Paul Ashwood   +4 more
doaj   +1 more source

Kinetic Changes of Peripheral Blood Monocyte Subsets and Expression of Co-Stimulatory Molecules during Acute Dengue Virus Infection

Pathogens, 2021
Monocytes, one of the main target cells for dengue virus (DENV) infection, contribute to the resolution of viremia and to pathogenesis. We performed a longitudinal study by a detailed phenotypic comparison of classical (CD14++CD16−, non-classical (CD14 ...
Sakaorat Lertjuthaporn, Rassamon Keawvichit, Korakot Polsrila, Kasama Sukapirom, Ampaiwan Chuansumrit, Kulkanya Chokephaibulkit, Aftab A. Ansari, Ladawan Khowawisetsut, Kovit Pattanapanyasat   +8 more
doaj   +1 more source

Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

Frontiers in Immunology, 2023
IntroductionMonocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated.
Tobias Schmidt, Tobias Schmidt, Alma Dahlberg, Alma Dahlberg, Elisabet Berthold, Petra Król, Petra Król, Sabine Arve-Butler, Sabine Arve-Butler, Emilia Rydén, Emilia Rydén, Seyed Morteza Najibi, Anki Mossberg, Anki Mossberg, Anders A. Bengtsson, Fredrik Kahn, Bengt Månsson, Robin Kahn, Robin Kahn   +18 more
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