Results 1 to 10 of about 314,823 (249)

Susceptibility to Infections During Acute Liver Injury Depends on Transient Disruption of Liver Macrophage Niche

Frontiers in Immunology, 2022
Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact ...
Mateus Eustáquio Lopes, Brenda Naemi Nakagaki, Matheus Silvério Mattos, Gabriel Henrique Campolina-Silva, Gabriel Henrique Campolina-Silva, Raquel de Oliveira Meira, Pierre Henrique de Menezes Paixão, André Gustavo Oliveira, Lucas D. Faustino, Ricardo Gonçalves, Gustavo Batista Menezes   +10 more
doaj   +1 more source

The Leukocyte Subtype Counts and Ratios Can Effectively Predict the Risk of Arterial Stiffness Assessed by Cardio-Ankle Vascular Index: A Retrospective Study

Frontiers in Cardiovascular Medicine, 2021
Background: Arterial stiffness was the pathological basis and risk factor of cardiovascular diseases, with chronic inflammation as the core characteristic.
Yaoling Wang, Ruiyun Wang, Lijuan Bai, Yun Liu, Lihua Liu, Linfeng He, Benling Qi   +6 more
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Case Report: Evolution of a Severe Vascular Refractory Form of ECD Requiring Liver Transplantation Correlated With the Change in the Monocyte Subset Analysis

Frontiers in Immunology, 2021
Erdheim–Chester disease is a rare histiocytosis characterized by iconic features associated with compatible histology. Most patients have somatic mutations in the MAP-kinase pathway gene, and the mutations occur in CD14+ monocytes. Differentiation of the
Jérôme Razanamahery, Anne Roggy, Jean-François Emile, Alexandre Malakhia, Zaher Lakkis, Francine Garnache-Ottou, Thibaud Soumagne, Fleur Cohen-Aubart, Julien Haroche, Bernard Bonnotte   +9 more
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Resistance Against Leishmania major Infection Depends on Microbiota-Guided Macrophage Activation

Frontiers in Immunology, 2021
Innate immune cells present a dual role during leishmaniasis: they constitute the first line of host defense but are also the main host cells for the parasite.
Mateus Eustáquio Lopes, Liliane Martins dos Santos, David Sacks, Leda Quercia Vieira, Matheus B. Carneiro   +4 more
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New Pharmacological Tools to Target Leukocyte Trafficking in Lung Disease

Frontiers in Immunology, 2021
Infection and inflammation of the lung results in the recruitment of non-resident immune cells, including neutrophils, eosinophils and monocytes. This swift response should ensure clearance of the threat and resolution of stimuli which drive inflammation.
Kylie B. R. Belchamber, Michael J. Hughes, Daniella A. Spittle, Eloise M. Walker, Elizabeth Sapey, Elizabeth Sapey   +5 more
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Monocyte‐to‐lymphocyte ratio as a predictor of stroke‐associated pneumonia: A retrospective study‐based investigation

Brain and Behavior, 2021
Background and purpose Early prediction of stroke‐associated pneumonia (SAP) is significant in clinical practice, as it is frequently challenging due to delays in typical clinical manifestations and radiological changes. The monocyte‐to‐lymphocyte ratio (
Feng Cao, Yu Wan, Chunyan Lei, LianMei Zhong, HongTao Lei, Haimei Sun, Xing Zhong, YaDan Xiao   +7 more
doaj   +1 more source

Mass cytometry and single-cell RNA sequencing reveal immune cell characteristics of active and inactive phases of Crohn’s disease

Frontiers in Medicine, 2023
ObjectivesFor Crohn’s disease (CD), the alternation of the active phase and inactive phase may be related to humoral immunity and cellular immunity. This study aims to understand the characteristics of immune cells in patients with active CD (CDa) and ...
Wenjia Lin, Shiying Liu, Zhuojian Huang, Haiwen Li, Tianyu Lu, Yongxin Luo, Jiamin Zhong, Zewen Xu, Yu Liu, Yanwu Li, Yanwu Li, Peiwu Li, Qian Xu, Jiazhong Cai, Jiazhong Cai, Huibiao Li, Xin-lin Chen   +16 more
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AFM negatively regulates the infiltration of monocytes to mediate sepsis-associated acute kidney injury

Frontiers in Immunology, 2023
BackgroundSepsis is organ dysfunction due to the host’s deleterious response to infection, and the kidneys are one of the organs damaged in common sepsis.
Caiyun Guo, Youling Fan, Youling Fan, Jiurong Cheng, Yingdong Deng, Xiangsheng Zhang, Yanna Chen, Huan Jing, Wenjun Li, Pei Liu, Jiaqi Xie, Wenjun Ning, Hongtao Chen, Jun Zhou   +13 more
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Ratio of lymphocyte to monocyte area under the curve as a novel predictive factor for severe infection in multiple sclerosis

Frontiers in Immunology, 2023
BackgroundIndividuals with multiple sclerosis (MS) are vulnerable to all types of infection, because MS itself involves immunodeficiency, in addition to involving treatment with immunosuppressants.
Junichiro Takahashi, Tomoko Okamoto, Youwei Lin, Reiko Saika, Atsuko Katsumoto, Wakiro Sato, Takashi Yamamura, Yuji Takahashi   +7 more
doaj   +1 more source

CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Viral myocarditis is characterized by leukocyte infiltration of the heart and cardiomyocyte death. We recently identified C‐C chemokine ligand (CCL) 17 as a proinflammatory effector of C‐C chemokine receptor 2–positive macrophages and ...
Guoshuai Feng, Cuige Zhu, Chieh‐Yu Lin, Andrea Bredemeyer, Irmgard Förster, Daniel Kreisel, Kory J. Lavine   +6 more
doaj   +1 more source