Results 11 to 20 of about 314,823 (249)

Ursolic acid induces the production of IL6 and chemokines in both adipocytes and adipose tissue

Adipocyte, 2020
Adipose tissue inflammation plays an important role in the regulation of glucose and lipids metabolism. It is unknown whether Ursolic acid (UA) could regulate adipose tissue inflammation, though it can regulate inflammation in many other tissues. In this
Bin Feng, Yingguo Zhu, Lijun Yan, Hui Yan, Xiaohua Huang, Dandan Jiang, Zhen Li, Lun Hua, Yong Zhuo, Zhengfeng Fang, Lianqiang Che, Yan Lin, Shengyu Xu, Chao Huang, Yuanfeng Zou, Lixia Li, De Wu   +16 more
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Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma

Frontiers in Oncology, 2023
Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the peripheral
Krystle L. Ong, Marcus D. Davis, Kalyn K. Purnell, Hannah Cutshall, Harish C. Pal, Ashley N. Connelly, Christian X. Fay, Valeriya Kuznetsova, Elizabeth E. Brown, Elizabeth E. Brown, Zdenek Hel, Zdenek Hel, Zdenek Hel   +12 more
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Monocyte-endothelial cell interactions in vascular and tissue remodeling

Frontiers in Immunology, 2023
Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or pathophysiological conditions to orchestrate inflammation, angiogenesis, or tissue remodeling.
Mireia Medrano-Bosch, Blanca Simón-Codina, Wladimiro Jiménez, Wladimiro Jiménez, Elazer R. Edelman, Pedro Melgar-Lesmes, Pedro Melgar-Lesmes, Pedro Melgar-Lesmes   +7 more
doaj   +1 more source

Effects of different obesogenic diets on joint integrity, inflammation and intermediate monocyte levels in a rat groove model of osteoarthritis

Frontiers in Physiology, 2023
Introduction: Obesogenic diets aggravate osteoarthritis (OA) by inducing low-grade systemic inflammation, and diet composition may affect OA severity. Here, we investigated the effect of diet on joint damage and inflammation in an OA rat model.Methods ...
K. Warmink, J. L. Rios, D. R. van Valkengoed, P. Vinod, N. M. Korthagen, N. M. Korthagen, H. Weinans, H. Weinans   +7 more
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Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

Frontiers in Immunology, 2023
IntroductionMonocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated.
Tobias Schmidt, Tobias Schmidt, Alma Dahlberg, Alma Dahlberg, Elisabet Berthold, Petra Król, Petra Król, Sabine Arve-Butler, Sabine Arve-Butler, Emilia Rydén, Emilia Rydén, Seyed Morteza Najibi, Anki Mossberg, Anki Mossberg, Anders A. Bengtsson, Fredrik Kahn, Bengt Månsson, Robin Kahn, Robin Kahn   +18 more
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CORRELATION TRIGLISERIDA LEVEL AND MONOCYTE IN CORONARY HEART DISEASE AT ULIN GENERAL HOSPITAL BANJARMASIN

Berkala Kedokteran, 2017
: Coronary heart disease (CHD) is an unbalance condition between oxygen supply and demand in heart muscle which caused by coronary artery obstruction known as atherosclerosis.
Gusti Adistya Naila Juwita, Miftahul Arifin, Ida Yuliana   +2 more
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Causal relationship between circulating immune cells and the risk of type 2 diabetes: a Mendelian randomization study

Frontiers in Endocrinology, 2023
ObjectivesThough type 2 diabetes (T2D) has been known as a metabolic disease caused by multiple factors, the etiology remains insufficiently understood.
Jin Li, Qingmin Niu, Aiwei Wu, Yuchu Zhang, Liquan Hong, Hu Wang   +5 more
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Swine barn dust stimulates CCL9 expression in mouse monocytes through protein kinase C-delta activation

Environmental Disease, 2020
Objective: Exposure to organic barn dusts has been shown to cause numerous lung problems to chronically exposed animal barn workers. Bacterial components in these dusts trigger innate immunity in the lungs.
David Schneberger, Jane M Devasure, Kristina L Bailey, Debra J Romberger, Todd A Wyatt   +4 more
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Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli

eLife, 2023
Bacterial pneumonia in neonates can cause significant morbidity and mortality when compared to other childhood age groups. To understand the immune mechanisms that underlie these age-related differences, we employed a mouse model of Escherichia coli ...
Sharon A McGrath-Morrow, Jarrett Venezia, Roland Ndeh, Nigel Michki, Javier Perez, Benjamin David Singer, Raffaello Cimbro, Mark Soloski, Alan L Scott   +8 more
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Bone Size and Quality Regulation: Concerted Actions of mTOR in Mesenchymal Stromal Cells and Osteoclasts

Stem Cell Reports, 2017
The bone size and quality, acquired during adolescent growth under the influence of anabolic hormones, growth factors, and nutrients, determine the height and bone stability and forecast osteoporosis risks in late life.
Hongguang Wu, Zhixiang Wu, Ping Li, Qian Cong, Rongrong Chen, Wenrui Xu, Soma Biswas, Huijuan Liu, Xuechun Xia, Shanshan Li, Weiwei Hu, Zhenlin Zhang, Samy L. Habib, Lingli Zhang, Jun Zou, Hongbing Zhang, Weihong Zhang, Baojie Li   +17 more
doaj   +1 more source