Results 11 to 20 of about 400,128 (308)

CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Viral myocarditis is characterized by leukocyte infiltration of the heart and cardiomyocyte death. We recently identified C‐C chemokine ligand (CCL) 17 as a proinflammatory effector of C‐C chemokine receptor 2–positive macrophages and ...
Guoshuai Feng   +6 more
doaj   +1 more source

Monocyte-endothelial cell interactions in vascular and tissue remodeling

open access: yesFrontiers in Immunology, 2023
Monocytes are circulating leukocytes of innate immunity derived from the bone marrow that interact with endothelial cells under physiological or pathophysiological conditions to orchestrate inflammation, angiogenesis, or tissue remodeling.
Mireia Medrano-Bosch   +7 more
doaj   +1 more source

Intermediate Monocytes with PD-L1 and CD62L Expression as a Possible Player in Active SARS-CoV-2 Infection

open access: yesViruses, 2022
Monocytes play a role in viral biology, but little is known about the monocyte subpopulation in the course of COVID-19 disease. The aim of the study was the analysis of classical, intermediate and non-classical monocytes with expression of PD-L1 and ...
Elżbieta Rutkowska   +4 more
doaj   +1 more source

Rab Geranylgeranyltransferase Subunit Beta as a Potential Indicator to Assess the Progression of Amyotrophic Lateral Sclerosis

open access: yesBrain Sciences, 2023
Background: Currently, there is no effective treatment for amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disorder. Many biomarkers have been proposed, but because ALS is a clinically heterogeneous disease with an unclear etiology ...
Jing Yang   +7 more
doaj   +1 more source

Causal relationship between circulating immune cells and the risk of type 2 diabetes: a Mendelian randomization study

open access: yesFrontiers in Endocrinology, 2023
ObjectivesThough type 2 diabetes (T2D) has been known as a metabolic disease caused by multiple factors, the etiology remains insufficiently understood.
Jin Li   +5 more
doaj   +1 more source

Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma

open access: yesFrontiers in Oncology, 2023
Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the peripheral
Krystle L. Ong   +12 more
doaj   +1 more source

Learning in a simple biological system: a pilot study of classical conditioning of human macrophages in vitro

open access: yesBehavioral and Brain Functions, 2011
Recent advances in cell biology and gene regulation suggest mechanisms whereby associative learning could be performed by single cells. Therefore, we explored a model of classical conditioning in human macrophages in vitro.
Nilsonne Gustav   +4 more
doaj   +1 more source

The Time Course of Monocytes Infiltration After Acoustic Overstimulation

open access: yesFrontiers in Cellular Neuroscience, 2022
Cochlea macrophages regulate cochlea inflammation and may harbors the potentials to protect hearing function from injury, including acoustic overstimulation. Cochlea macrophage numbers increase at 3–7 days after acoustic stimulation.
Seung Ho Shin   +7 more
doaj   +1 more source

Assessing the Functional Heterogeneity of Monocytes in Human Septic Shock: a Proof-of-Concept Microfluidic Assay of TNFα Secretion

open access: yesFrontiers in Immunology, 2021
ObjectiveThe development of advanced single-cell technologies to decipher inter-cellular heterogeneity has enabled the dynamic assessment of individual cells behavior over time, overcoming the limitation of traditional assays.
Jean-François Llitjos   +17 more
doaj   +1 more source

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