Results 21 to 30 of about 314,823 (249)

Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses

open access: yesFrontiers in Immunology, 2018
Amino acids (AAs) are necessary nutrients which act not only as building blocks in protein synthesis but also in crucial anabolic cellular signaling pathways.
Bo Ruem Yoon   +9 more
doaj   +1 more source

Circulating Myeloid Regulatory Cells: Promising Biomarkers in B-Cell Lymphomas

open access: yesFrontiers in Immunology, 2021
The monocyte/macrophage lineage has been shown to be involved in the promotion of a protumoral tumor microenvironment and resistance to treatment in B cell lymphomas.
Juliette Ferrant   +7 more
doaj   +1 more source

Elevated TNF-α Induces Thrombophagocytosis by Mononuclear Cells in ex vivo Whole-Blood Co-Culture with Dengue Virus

open access: yesJournal of Inflammation Research, 2022
Rahmat Dani Satria,1– 4,* Ming-Kai Jhan,4,5,* Chia-Ling Chen,6 Po-Chun Tseng,4,7 Yung-Ting Wang,4 Chiou-Feng Lin4,5,7 1International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan; 2Department of ...
Satria RD   +5 more
doaj  

Systemic Immune-Inflammatory Index as a Predictor of Lymph Node Metastasis in Endometrial Cancer

open access: yesJournal of Inflammation Research, 2021
HuiFang Lei,1,2,* ShuXia Xu,3,* XiaoDan Mao,1,2 XiaoYing Chen,4 YaoJia Chen,1,2 XiaoQi Sun,4 PengMing Sun1,2,4 1Laboratory of Gynecologic Oncology, Department of Gynecology, Fujian Provincial Maternity and Children’s Hospital, Affiliated Hospital
Lei H   +6 more
doaj  

The Time Course of Monocytes Infiltration After Acoustic Overstimulation

open access: yesFrontiers in Cellular Neuroscience, 2022
Cochlea macrophages regulate cochlea inflammation and may harbors the potentials to protect hearing function from injury, including acoustic overstimulation. Cochlea macrophage numbers increase at 3–7 days after acoustic stimulation.
Seung Ho Shin   +7 more
doaj   +1 more source

Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium

open access: yesFrontiers in Immunology, 2020
Asthma exacerbations, a major concern in therapeutic strategies, are most commonly triggered by viral respiratory infections, particularly with human rhinovirus (HRV).
Benoit Allard   +20 more
doaj   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Expression and Functions of the CB2 Receptor in Human Leukocytes

open access: yesFrontiers in Pharmacology, 2022
The cannabinoid CB2 receptor was cloned from the promyeloid cell line HL-60 and is notably expressed in most, if not all leukocyte types. This relatively restricted localization, combined to the absence of psychotropic effects following its activation ...
Mélissa Simard   +10 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

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