Results 211 to 220 of about 85,833 (243)

Differential role of monocyte subsets in atherosclerosis

Thrombosis and Haemostasis, 2011
SummaryEndothelial dysfunction and inflammation of the arterial wall continuously drive the development of atherosclerosis. Details regarding the sequential involvement of different monocyte subsets in the pathology of this disease have recently emerged.
M, Hristov, C, Weber
openaire   +2 more sources

Monocytes: subsets, origins, fates and functions

Current Opinion in Hematology, 2010
The term mono-cyte suggests this population of cells consists of a single homogenous fraction. However, evidence from a number of laboratories indicates that monocytes are composed of several subsets, which differ in phenotype, size, nuclear morphology, granularity and gene profiles.
Simon, Yona, Steffen, Jung
openaire   +2 more sources

Monocyte subsets and monocyte-platelet aggregates in patients with unstable angina

Journal of Thrombosis and Thrombolysis, 2014
Monocyte subsets and monocyte-platelet aggregates (MPAs) play important role in atherosclerosis and thrombosis. We aimed to determine their changes in patients with unstable angina (UA). In this cross-sectional case-control study, Global Registry of Acute Coronary Events (GRACE) score was determined in 95 UA patients without elevated troponin level ...
Shan, Zeng, Xin, Zhou, Lan, Ge, Wen-Jie, Ji, Rui, Shi, Rui-Yi, Lu, Hai-Ying, Sun, Zhao-Zeng, Guo, Ji-Hong, Zhao, Tie-Min, Jiang, Yu-Ming, Li   +10 more
openaire   +2 more sources

SuperSAGE evidence for CD14++CD16+ monocytes as a third monocyte subset

Blood, 2011
Abstract Monocytes are a heterogeneous cell population with subset-specific functions and phenotypes. The differential expression of CD14 and CD16 distinguishes classical CD14++CD16−, intermediate CD14++CD16+, and nonclassical CD14+CD16++ monocytes.
Adam M, Zawada, Kyrill S, Rogacev, Björn, Rotter, Peter, Winter, Rolf-R, Marell, Danilo, Fliser, Gunnar H, Heine   +6 more
openaire   +2 more sources

Aberrant monocyte subsets in patients with Behçet's disease

Clinical Immunology, 2021
Monocytes are a versatile and dynamic population, but its implication in Behçet's Disease (BD) remains elusive. We investigated the proportion, phenotypical and functional alterations in classical monocytes (CM), intermediate monocytes (IM) and non-classical monocytes (NCM) subsets in BD.
Chaoran, Li, Jinjing, Liu, Xin, Yu, Lu, Li, Zhimian, Wang, Jing, Shi, Xiaofeng, Zeng, Fengchun, Zhang, Hua, Chen, Wenjie, Zheng   +9 more
openaire   +2 more sources

Monocyte subsets in man and other species

Cellular Immunology, 2014
Monocytes are white blood cells that belong to the mononuclear phagocyte system. They derive from precursors in bone marrow, from there they go into blood, where they have a half-life of 1-2 days, and then they migrate into the various tissues. Monocyte subsets were discovered by means of flow cytometry in human blood some 20 years ago and their ...
openaire   +2 more sources

Functional Analysis of Monocyte Subsets in Surgical Sepsis

The Journal of Trauma: Injury, Infection, and Critical Care, 1997
Sepsis still remains a major cause of death after surgery. Impaired monocyte (Mphi) function and disruption of monocyte (Mphi/T-cell interaction were shown to be crucial for the development of septic complications in these patients. It was the objective of the study to assess more insights in Mphi behavior in surgical sepsis by means of analysis of Fc ...
C, Schinkel, R, Sendtner, S, Zimmer, E, Faist   +3 more
openaire   +2 more sources

Unique monocyte subset in patients with AIDS dementia

The Lancet, 1997
15-30% of patients infected with HIV will develop a debilitating dementia. Whilst HIV enters the brain soon after infection, presumably within monocyte-derived macrophages, not all patients with HIV become demented. Blood monocytes probably cross the blood-brain barrier and give rise ultimately to parenchyma macrophages.
L, Pulliam, R, Gascon, M, Stubblebine, D, McGuire, M S, McGrath   +4 more
openaire   +2 more sources

Isolation and Characterization of Human Monocyte Subsets

1982
Human peripheral blood monocytes manifest several functions in vitro that are thought to be important to host defenses. Monocytes and/or their more differentiated forms exhibit chemotaxis, phagocytosis, bacterial killing, tumor cytotoxicity, and modulation of immunity and hematopoiesis.
openaire   +2 more sources

Heterogeneity of human peripheral blood monocyte subsets

Journal of Leukocyte Biology, 2001
AbstractIn recent years the number of reports describing phenotypically and functionally distinct subsets of human blood leukocytes, and in particular of subtypes of antigen-presenting cells has continuously increased. A great diversity was described not only for dendritic cells (DC), but also for human blood monocytes (Mo) and macrophages (Mac ...
E, Grage-Griebenow, H D, Flad, M, Ernst
openaire   +2 more sources