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Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention
Frontiers in Immunology, 2022 BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this study was to analyze the monocyte subset composition (classical (CM), intermediate (IM) and non-
Eline S. van der Valk +9 more
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The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood
Frontiers in Immunology, 2023 IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Nicola Tamassia +12 more
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Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Nature reviews. Immunology, 2020 The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease severity and death in ...
M. Merad, Jérôme C. Martin
semanticscholar +1 more source
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes
Cell Death Discovery, 2021 Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in critically ill patients.
André C. Ferreira +18 more
semanticscholar +1 more source
Monocytes and Macrophages in COVID-19
Frontiers in Immunology, 2021 COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing pandemic with massive global health and socioeconomic consequences.
Rainer Knoll +2 more
semanticscholar +1 more source
CCR2 Signaling Restricts SARS-CoV-2 Infection
mBio, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a historic pandemic of respiratory disease (coronavirus disease 2019 [COVID-19]), and current evidence suggests that severe disease is associated with dysregulated immunity within ...
Abigail Vanderheiden +17 more
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Scientific Reports, 2021 Monocytes are important mediators of immune system and are reported to be altered in autoimmune disorders. Little is known about the pathological role of monocytes in Graves’ disease (GD).
Xinxin Chen +9 more
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Ammonia-induced Calcium Phosphate Nanostructure: A Potential Assay for Studying Osteoporosis and Bone Metastasis [PDF]
ACS Applied Materials & Interfaces Manuscript ID:
am-2021-004953.R2, 2021 Osteoclastic resorption of bone plays a central role in both osteoporosis and bone metastasis. A reliable in vitro assay that simulates osteoclastic resorption in vivo would significantly speed up the process of devel-oping effective therapeutic solutions for those diseases. Here we reported the development of a novel and robust nano-structured calcium
arxiv +1 more source
Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients
National Science Review, 2020 Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity and mortality1, 2 Recently, a severe pneumonia-associated respiratory syndrome ...
Yonggang Zhou +9 more
semanticscholar +1 more source
Helicobacter pylori Infection of Primary Human Monocytes Boosts Subsequent Immune Responses to LPS
Frontiers in Immunology, 2022 Infection with Helicobacter pylori (H. pylori) affects almost half of the world’s population and is a major cause of stomach cancer. Although immune cells react strongly to this gastric bacterium, H.
Tobias Frauenlob +9 more
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