Results 91 to 100 of about 613,326 (371)

Immunohistochemical detection of monocytes by the antiserum specific to monocytic esterase. [PDF]

Journal of Histochemistry & Cytochemistry, 1985
An antiserum specific to esterase Ib was produced in a rabbit. The antigen-antibody reaction was visualized by the strong esterase activity in the precipitin band in Ouchterlony double diffusion and immunoelectrophoresis. Immunohistochemical procedure demonstrated strong staining in the monocyte-infiltrated splenic sections and tissue sections of true
Lung-T Yam, Kwok-Wai Lam, M. Siemens, C. Y. Li   +3 more
openaire   +3 more sources

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Monocyte and T-lymphocyte trans-endothelial migration in relation to cardiovascular disease: some alternative boundary conditions in a model recently proposed by Little et al. (PLoS Comput Biol 2009 5(10) e1000539) [PDF]

arXiv, 2010
We consider a slight modification to the monocyte and T-lymphocyte boundary conditions of Little et al. (PLoS Comput Biol 2009 5(10) e1000539) and derive alternative parameter estimates. No changes to the results and conclusions of the paper of Little et al. (PLoS Comput Biol 2009 5(10) e1000539) are implied.
arxiv  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

HIF-1α regulates IL-1β and IL-17 in sarcoidosis

eLife, 2019
Sarcoidosis is a complex systemic granulomatous disease of unknown etiology characterized by the presence of activated macrophages and Th1/Th17 effector cells.
Jaya Talreja, Harvinder Talwar, Christian Bauerfeld, Lawrence I Grossman, Kezhong Zhang, Paul Tranchida, Lobelia Samavati   +6 more
doaj   +1 more source

Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Proceedings of the National Academy of Sciences of the United States of America, 2012
Adaptive features of innate immunity, recently described as “trained immunity,” have been documented in plants, invertebrate animals, and mice, but not yet in humans.
J. Kleinnijenhuis, J. Quintin, F. Preijers, L. Joosten, D. Ifrim, Sadia Saeed, C. Jacobs, J. van Loenhout, D. D. de Jong, H. Stunnenberg, R. Xavier, J. V. D. van der Meer, R. van Crevel, M. Netea   +13 more
semanticscholar   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

In vivo Differentiation of Human Monocytes

Frontiers in Immunology, 2019
Circulating monocytes can infiltrate mucosal or inflamed tissues where they differentiate into either macrophages or dendritic cells. This paradigm is supported by numerous studies conducted in mice and in different in vitro settings for human cells ...
Alice Coillard, É. Segura
semanticscholar   +1 more source

Hold On, the Monocytes Are Coming! [PDF]

Immunity, 2007
The role that monocyte-derived dendritic cells play in vivo remains enigmatic. León et al. (2007) now show that these cells develop "on demand" at a site of Leishmania infection to promote a life-saving T helper 1 immune response.
openaire   +3 more sources

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source