Results 191 to 200 of about 737,831 (351)

A TLR8 Variant Identified From Whole Exome Sequencing as a Sepsis-Prone Mutation. [PDF]

FASEB Bioadv
Alhamdan F, Gianoli S, Han X, Koutsogiannaki S.   +3 more
europepmc   +1 more source

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

Advanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li, Yuxin Wu, Shuai Zhou, Peipei Tang, Jiaming Wei, Ling Liu, Zhenyi Wang, Deyang Shi, Shengnan Yuan, Qingyu Zhang, Shihui Wang, Qing Zhang, Huan Zhao, Rui Zhang, Yingying Wang, Shiwei Yang, Xiangli Chen, Xiaojing Shi, Guangzhi Liu, Yuwei Zhang, Jinming Li, Xu Dong Zhang, Rick F Thorne, Dongping Wei, Zumin Zhu, Song Chen   +25 more
wiley   +1 more source

Integrated analysis of sex differences in human dendritic cell, monocyte, and natural killer cell subsets. [PDF]

Front Immunol
Yang Y, Chen L, Shang M, Cao Q, Zhang M, Zhang L, Wang J, Tong X, Sun X.   +8 more
europepmc   +1 more source

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

Advanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu, Kexing Li, Yuge Wang, Hongyu Li, Hongyu Zhao   +4 more
wiley   +1 more source

Transient miR-92a Induction in Intermediate Monocytes (CD14⁺⁺CD16⁺) in Acute Coronary Syndrome (ACS). [PDF]

Int J Mol Sci
Harbaum L, Kreutz J, Weibler C, Euler G, Malysa M, Raifer H, Schieffer B, Grote K, Parahuleva M.   +8 more
europepmc   +1 more source

Secreted Ectodomain of Sialic Acid-Binding Ig-Like Lectin-9 and Monocyte Chemoattractant Protein-1 Promote Recovery after Rat Spinal Cord Injury by Altering Macrophage Polarity [PDF]

, 2015
Kohki Matsubara, Yoshihiro Matsushita, Kiyoshi Sakai, Fumiya Kano, Megumi Kondo, Mariko Noda, Noboru Hashimoto, Shiro Imagama, Naoki Ishiguro, Akio Suzumura, Minoru Ueda, Koichi Furukawa, Akihito Yamamoto   +12 more
openalex   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Cold Atmospheric Pressure Plasma Treatment Modulates Human Monocytes/Macrophages Responsiveness [PDF]

, 2018
Letizia Crestale, Romolo Laurita, Anna Liguori, Augusto Stancampiano, Maria Talmon, Alina Bisag, Matteo Gherardi, Angela Amoruso, Vittorio Colombo, Luigia Grazia Fresu   +9 more
openalex   +1 more source

Supplementary Material for: The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent

, 2021
Cuevas V.D., Miriam Simón‐Fuentes, Emmanuel Orta‐Zavalza, Rafael Samaniego, Paloma Sánchez‐Mateos, María M. Escribese, Cimas F.J., Matilde Bustos, Mario Pérez‐Diego, Alberto Ocaña, Ángeles Domínguez‐Soto, Vega M.A., Corbí Á.L.   +12 more
openalex   +1 more source

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses [PDF]

, 2016
et al,, Randolph, Gwendalyn J
core   +2 more sources