Results 41 to 50 of about 613,326 (371)
Frontiers in Immunology, 2021 Malaria complications are often lethal, despite efficient killing of Plasmodium parasites with antimalarial drugs. This indicates the need to study the resolution and healing mechanisms involved in the recovery from these complications.
Emilie Pollenus +7 more
doaj +1 more source
Studying the Innate Immune Response to Myocardial Infarction in a Highly Efficient Experimental Animal Model [PDF]
Romanian Journal of Cardiology, 2021 The reduction in mortality following acute myocardial infarction (AMI) is an important achievement of modern medicine. Despite this progress, AMI remains the most common cause of heart failure (HF) and HF-related morbidity and mortality.
Razvan Gheorghita MARES +9 more
doaj +1 more source
From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation
Frontiers in Immunology, 2014 Studies on monocyte and macrophage biology and differentiation have revealed the pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue integrity by eliminating/repairing damaged cells and matrices.
P. Italiani, D. Boraschi
semanticscholar +1 more source
Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia
EMBO Molecular Medicine, 2020 In patients infected by SARS‐CoV‐2 who experience an exaggerated inflammation leading to pneumonia, monocytes likely play a major role but have received poor attention.
L. Gibellini +19 more
semanticscholar +1 more source
Granulocyte‐Monocyte Progenitors and Monocyte‐Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes [PDF]
Immunity, 2017 Granulocyte-monocyte progenitors (GMPs) and monocyte-dendritic cell progenitors (MDPs) produce monocytes during homeostasis and in response to increased demand during infection. Both progenitor populations are thought to derive from common myeloid progenitors (CMPs), and a hierarchical relationship (CMP-GMP-MDP-monocyte) is presumed to underlie ...
A. Yáñez +8 more
semanticscholar +6 more sources
Hematology, 1998 Human monocytes may play a central role in haemostasis since they are the only circulating blood cells capable to express tissue factor (TF) and therefore trigger the extrinsic pathway of coagulation. The aim of this review is to illustrate that monocytes also participate in haemostasis independently of TF expression.
Matthieu Broussas +3 more
openaire +3 more sources
Frontiers in Immunology, 2017 Monocytes and the recruitment of monocyte-derived macrophages into sites of inflammation play a key role in atherogenesis and other chronic inflammatory diseases linked to cardiometabolic syndrome and obesity.
John D. Short +9 more
doaj +1 more source
Frontiers in Immunology, 2019 Recent successes in cancer immunotherapy have been tempered by sub-optimal clinical responses in the majority of patients. The impaired anti-tumor immune responses observed in these patients are likely a consequence of immune system dysfunction ...
April E. Mengos +2 more
doaj +1 more source
Poly-l-lysine-caused cell adhesion induces pyroptosis in THP-1 monocytes
Open Life Sciences, 2022 Pyroptosis is a kind of cell necrosis mediated by inflammasomes. The caspase 1-induced cleavage of gasdermin D (GSDMD) is a canonical pathway to cause membrane pores and eventually cell pyroptosis.
Yu Chaoping +4 more
doaj +1 more source
Frontiers in Medicine, 2021 Age-related macular degeneration (AMD) is characterized by the accumulation of debris in the posterior eye. In this study we evaluated peripheral blood monocyte phagocytic function at various stages of AMD and in aged matched control participants.
Ben J. Gu +15 more
doaj +1 more source