Results 51 to 60 of about 613,326 (371)

Transglutaminases in Monocytes and Macrophages [PDF]

Medical Sciences, 2018
Macrophages are key players in various inflammatory disorders and pathological conditions via phagocytosis and orchestrating immune responses. They are highly heterogeneous in terms of their phenotypes and functions by adaptation to different organs and tissue environments.
Huifang Sun, Mari T. Kaartinen
openaire   +3 more sources

Disruption in the Regulation of Immune Responses in the Placental Subtype of Preeclampsia

Frontiers in Immunology, 2018
Preeclampsia is a pregnancy-specific disorder, of which one of its major subtypes, the placental subtype is considered a response to an ischemic placental environment, impacting fetal growth and pregnancy outcome.
Janri Geldenhuys, Theresa Marie Rossouw, Hendrik Andries Lombaard, Marthie Magdaleen Ehlers, Marthie Magdaleen Ehlers, Marleen Magdalena Kock, Marleen Magdalena Kock   +6 more
doaj   +1 more source

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells

Nature Communications, 2016
Self-renewing tissue-resident macrophages are thought to be exclusively derived from embryonic progenitors. However, whether circulating monocytes can also give rise to such macrophages has not been formally investigated.
Charlotte L. Scott, Fang Zheng, P. De Baetselier, L. Martens, Y. Saeys, Sofie De Prijck, S. Lippens, C. Abels, S. Schoonooghe, G. Raes, N. Devoogdt, B. Lambrecht, A. Beschin, M. Guilliams   +13 more
semanticscholar   +1 more source

Local proliferation of monocytes [PDF]

Journal of Leukocyte Biology, 2020
AbstractDiscussion on how monocytes may contribute to the expansion of Mϕ populations at the site of inflammation.
Stephen J. Jenkins, Johanna A. Knipper, Dietmar M. W. Zaiss   +2 more
openaire   +3 more sources

Role of Myeloid-Epithelial-Reproductive Tyrosine Kinase and Macrophage Polarization in the Progression of Atherosclerotic Lesions Associated With Nonalcoholic Fatty Liver Disease

Frontiers in Pharmacology, 2019
Recent lines of evidence highlight the involvement of myeloid-epithelial-reproductive tyrosine kinase (MerTK) in metabolic disease associated with liver damage.
Mirella Pastore, Stefania Grimaudo, Rosaria Maria Pipitone, Giulia Lori, Chiara Raggi, Chiara Raggi, Salvatore Petta, Fabio Marra   +7 more
doaj   +1 more source

Monocyte biomarkers define sargramostim treatment outcomes for Parkinson's disease

Clinical and Translational Medicine, 2022
Background Dysregulation of innate and adaptive immunity heralds both the development and progression of Parkinson's disease (PD). Deficits in innate immunity in PD are defined by impairments in monocyte activation, function, and pro‐inflammatory ...
Mai M. Abdelmoaty, Jatin Machhi, Pravin Yeapuri, Farah Shahjin, Vikas Kumar, Katherine E. Olson, R. Lee Mosley, Howard E. Gendelman   +7 more
doaj   +1 more source

Antcin K inhibits VCAM-1-dependent monocyte adhesion in human rheumatoid arthritis synovial fibroblasts

Food & Nutrition Research, 2022
Background: Antcin K, an extract of Antrodia cinnamomea (a medicinal mushroom endemic to Taiwan commonly used in Chinese medicine preparations), inhibits proinflammatory cytokine production and angiogenesis in human rheumatoid arthritis synovial ...
David Achudhan, Sunny Li-Yun Chang, Shan-Chi Liu, Yen-You Lin, Wei-Chien Huang, Yang-Chang Wu, Chien-Chung Huang, Chun-Hao Tsai, Chih-Yuan Ko, Yueh-Hsiung Kuo, Chih-Hsin Tang   +10 more
doaj   +1 more source

Roles for Cell-Cell Adhesion and Contact in Obesity-Induced Hepatic Myeloid Cell Accumulation and Glucose Intolerance

Cell Reports, 2017
Obesity promotes infiltration of inflammatory cells into various tissues, leading to parenchymal and stromal cell interaction and development of cellular and organ dysfunction.
Yasutaka Miyachi, Kyoichiro Tsuchiya, Chikara Komiya, Kumiko Shiba, Noriko Shimazu, Shinobu Yamaguchi, Michiyo Deushi, Mizuko Osaka, Kouji Inoue, Yuta Sato, Sayaka Matsumoto, Junichi Kikuta, Kenjiro Wake, Masayuki Yoshida, Masaru Ishii, Yoshihiro Ogawa   +15 more
doaj   +1 more source

Proteomic Signatures of Monocytes in Hereditary Recurrent Fevers

Frontiers in Immunology, 2022
Hereditary periodic recurrent fevers (HRF) are monogenic autoinflammatory associated to mutations of some genes, such as diseases caused by mutations of including MEFV, TNFRSF1A and MVK genes.
Federica Penco, Andrea Petretto, Chiara Lavarello, Riccardo Papa, Arinna Bertoni, Alessia Omenetti, Ilaria Gueli, Martina Finetti, Roberta Caorsi, Stefano Volpi, Marco Gattorno   +10 more
doaj   +1 more source

How cells tiptoe on adhesive surfaces before sticking [PDF]

Biophysical Journal 94 (2008) 4114, 2008
Cell membranes are studded with protrusions that were thoroughly analyzed with electron microscopy. However, the nanometer-scale three-dimensional motions generated by cell membranes to fit the topography of foreign surfaces and initiate adhesion remain poorly understood.
arxiv   +1 more source