Results 61 to 70 of about 875,934 (414)
Hematology, 1998 Human monocytes may play a central role in haemostasis since they are the only circulating blood cells capable to express tissue factor (TF) and therefore trigger the extrinsic pathway of coagulation. The aim of this review is to illustrate that monocytes also participate in haemostasis independently of TF expression.
Matthieu Broussas +3 more
openaire +3 more sources
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis [PDF]
, 2015 Tuberculosis (TB) remains a global pandemic and drug resistance is rising. Multicellular granuloma formation is the pathological hallmark of Mycobacterium tuberculosis infection.
Brilha, S +8 more
core +2 more sources
Transglutaminases in Monocytes and Macrophages [PDF]
Medical Sciences, 2018 Macrophages are key players in various inflammatory disorders and pathological conditions via phagocytosis and orchestrating immune responses. They are highly heterogeneous in terms of their phenotypes and functions by adaptation to different organs and tissue environments.
Huifang Sun, Mari T. Kaartinen
openaire +3 more sources
From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation
Frontiers in Immunology, 2014 Studies on monocyte and macrophage biology and differentiation have revealed the pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue integrity by eliminating/repairing damaged cells and matrices.
P. Italiani, D. Boraschi
semanticscholar +1 more source
Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes [PDF]
, 2020 Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes.
Esmaeil, Nafiseh +3 more
core +2 more sources
The monocyte-macrophage axis in the intestine [PDF]
, 2014 Macrophages are one of the most abundant leucocytes in the intestinal mucosa where they are essential for maintaining homeostasis. However, they are also implicated in the pathogenesis of disorders such as inflammatory bowel disease (IBD), offering ...
Ajami +105 more
core +2 more sources
mSphere, 2018 Zika virus (ZIKV) has reemerged in the population and caused unprecedented global outbreaks. Here, the transcriptomic consequences of ZIKV infection were studied systematically first in human peripheral blood CD14+ monocytes and monocyte-derived ...
Fok-Moon Lum +15 more
doaj +1 more source
Local proliferation of monocytes [PDF]
Journal of Leukocyte Biology, 2020 AbstractDiscussion on how monocytes may contribute to the expansion of Mϕ populations at the site of inflammation.
Stephen J. Jenkins +2 more
openaire +3 more sources
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells
Nature Communications, 2016 Self-renewing tissue-resident macrophages are thought to be exclusively derived from embryonic progenitors. However, whether circulating monocytes can also give rise to such macrophages has not been formally investigated.
Charlotte L. Scott +13 more
semanticscholar +1 more source
Janus-like monocytes regulate postoperative ileus [PDF]
, 2017 No abstract ...
Mowat, Allan McI
core +1 more source