Results 151 to 160 of about 106,988 (276)

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

open access: yesJournal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios   +8 more
wiley   +1 more source

An Archaeometric Approach to Reveal Organic Compounds via GC‐MS Analyses of Two Discovered Incense Burners at Daba Al‐Bayah

open access: yesArchaeometry, EarlyView.
ABSTRACT This study focuses on two terracotta incense burners discovered in the Daba Al‐Bayah necropolis in the Musandam Peninsula (Oman), associated with an Iron Age collective tomb (LCG‐2). Through gas chromatography–mass spectrometry (GC‐MS), the organic residues preserved within these artifacts were analyzed to investigate their use and ...
Francesco Genchi   +3 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Sustainable dyeing of silk with curled dock (Rumex crispus) extract for trace element removal, ultraviolet protection, antimicrobial and anti‐oxidant activity

open access: yesColoration Technology, EarlyView.
Abstract This study investigated the dyeability and functionality of silk dyed with curled dock leaf extract. The effects of sugar content and turbidity in the extracted dye solution on dyeing were analysed, along with K/S values and colour fastness, under varying temperatures and times.
Youngmi Park
wiley   +1 more source

Protein nanoparticles assemble in plants, display antigenic viral peptides, and produce an epitope‐specific immune response

open access: yesThe FEBS Journal, EarlyView.
Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt   +5 more
wiley   +1 more source

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