The application of a novel hydrodynamic cavitation device to debride intra-articular monosodium urate crystals [PDF]
BMC Surgery, 2023 Introduction Efficient and complete debridement of intra-articular deposits of monosodium urate crystals is rarely achieved by existing arthroscopic tools such as shavers or radiofrequency ablation, while cavitation technology represents a prospective ...
Hanlin Xu +6 more
doaj +2 more sources
Cynarin suppresses gouty arthritis induced by monosodium urate crystals. [PDF]
Bioengineered, 2022 The study is aimed to determine the effects of cynarin (Cyn) on mice with gouty arthritis (GA) induced by monosodium urate (MSU). We measured swelling in the hind paws of mice in vivo using Vernier calipers and ultrasound. The liver, kidney, and hind paws were stained with hematoxylin-eosin, and M1 type macrophages were detected in the hind paws using ...
Wu C +12 more
europepmc +3 more sources
Inhibition of Monosodium Urate Crystal-Induced Inflammation by Withaferin A
Journal of Pharmacy & Pharmaceutical Sciences, 2009 Purpose. Gouty arthritis is a characteristically intense acute inflammatory reaction resulting from the formation of sodium urate crystals in the joint cavity.
Mahaboobkhan Rasool +2 more
doaj +4 more sources
Detection of intracellular monosodium urate crystals in gout synovial fluid using optical diffraction tomography [PDF]
Scientific Reports, 2021 Optical diffraction tomography (ODT) enables imaging of unlabeled intracellular components by measuring the three-dimensional (3D) refractive index (RI). We aimed to detect intracellular monosodium urate (MSU) crystals in synovial leukocytes derived from
Sangwoo Park +10 more
doaj +2 more sources
Phagocytosis of monosodium urate crystals by human synoviocytes induces inflammation. [PDF]
Exp Biol Med (Maywood), 2019 Synovial cells play a crucial part in gouty arthritis, with different features for the inflammation within the joint. However, there is no information about how the synoviocytes can mediate the activation of inflammation. We hypothesized that the process of monosodium urate (MSU) crystal uptake alters the inflammatory response of synoviocytes through ...
Zamudio-Cuevas Y +8 more
europepmc +4 more sources
Osteogenic Potential of Monosodium Urate Crystals in Synovial Mesenchymal Stem Cells [PDF]
Medicina (Lithuania), 2022 CARLOS Landa-Solis +2 more
exaly +2 more sources
7-Methylxanthine Inhibits the Formation of Monosodium Urate Crystals by Increasing Its Solubility [PDF]
Biomolecules, 2023 Felix Grases +2 more
exaly +2 more sources
Study on the pro-inflammatory injury of neutrophil extracellular traps in gouty nephropathy [PDF]
Frontiers in ImmunologyGouty nephropathy is a common complication of gout, which is characterized pathologically by the abnormal deposition of urate crystals in the kidneys.
Shuliang Pu +7 more
doaj +2 more sources
Astaxanthin attenuates joint inflammation induced by monosodium urate crystals [PDF]
FASEB Journal, 2020 Abstract Gouty arthritis is the one of the most painful arthritis and is caused by an inflammatory reaction. This study investigated whether astaxanthin (AXT), which has documented anti‐inflammatory and antioxidant properties, exhibits protective effects against monosodium urate (MSU) crystal‐induced inflammation.
Chih-Chien Wang +2 more
exaly +3 more sources
Monosodium urate crystals induce oxidative stress in human synoviocytes. [PDF]
Arthritis Res Ther, 2016 النقرس هو اعتلال المفاصل الالتهابي الأكثر شيوعًا من أصل استقلابي ويتميز بالالتهاب الشديد، والآليات الكامنة وراءه غير معروفة. كان الهدف من هذه الدراسة هو تقييم الإجهاد التأكسدي في الخلايا الزليلية الشبيهة بالخلايا الليفية البشرية (FLS) المعرضة لبلورات يورات أحادي الصوديوم (MSU)، والتي تؤدي إلى عملية التهابية.
Zamudio-Cuevas Y +15 more
europepmc +4 more sources