Results 21 to 30 of about 5,891 (174)
Inhibition of monosodium urate needle crystal growth [PDF]
Arthritis & Rheumatism, 1965 AbstractA study of the growth of needle crystals of monosodium urate was undertaken with the aim of finding inhibitors which might be able to prevent the acute gout attack. Rates of crystal growth at various levels of supersaturation are described. Two potent crystal growth inhibitors, Bismarck brown and methylene blue, were found. They are shown to be
D J, Allen, G, Milosovich, A M, Mattocks
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Immunoglobulin in Tophi and on the Surface of Monosodium Urate Crystals [PDF]
Arthritis & Rheumatism, 1978 AbstractBy means of immunohistologic techniques IgG, IgM, and to a lesser degree, IgA were found in the inter‐crystalline matrix of gouty tophi. Smaller amounts of IgG and IgM were inconstantly found in association with tissue deposits of calcium pyrophosphate.
P, Hasselbacher, H R, Schumacher
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Revisiting the pathogenesis of podagra: why does gout target the foot?
Journal of Foot and Ankle Research, 2011 This invited paper provides a summary of a keynote lecture delivered at the 2011 Australasian Podiatry Conference. Gout is the most prevalent inflammatory arthropathy.
Roddy Edward
doaj +1 more source
Data in Brief, 2019 The data supplied in this work are related to the research article entitled “IL-17A neutralizing antibody regulates monosodium urate crystal-induced gouty inflammation” [1].
Federica Raucci +7 more
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Detection and identification of crystals in synovial fluid
Reumatismo, 2011 Synovial fluid analysis for crystals represents one of the most important laboratory test for the evaluation of rheumatic diseases. The identification of monosodium urate and calcium pyrophosphate dihydrate crystals allows the prompt diagnosis of gout ...
E. Pascual, F. Oliviero, L. Punzi
doaj +3 more sources
Urate-induced epigenetic modifications in myeloid cells
Arthritis Research & Therapy, 2021 Objectives Hyperuricemia is a metabolic condition central to gout pathogenesis. Urate exposure primes human monocytes towards a higher capacity to produce and release IL-1β. In this study, we assessed the epigenetic processes associated to urate-mediated
M. Badii +18 more
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Diagnostics, 2022 Background: This study examines the relationship between the presence of crystals in the synovial fluid of patients with psoriatic arthritis (PsA) and disease activity.
Mariela Geneva-Popova +3 more
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Metabolism of crystals within the joint
Reumatismo, 2012 Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage.
A. Scanu, F. Oliviero, L. Punzi
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BMC Rheumatology, 2020 Background A definite diagnosis of gout requires demonstration of monosodium urate crystals in synovial fluid or in tophi, which in clinical practice today seldom is done.
Elin Svensson +5 more
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Tophaceous gout of the male genitalia: A rare manifestation of chronic gout
Urology Case Reports, 2023 Gout is a metabolic disorder characterized by hyperuricemia and deposition of monosodium urate crystals in the joint spaces and other extraarticular locations.
Mustafa Farooqi +2 more
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