Results 81 to 90 of about 5,891 (174)

An unusual imaging finding mimicking double contour sign following ultrasound-guided intra-articular knee injection of steroid: A case report

Ağrı
Examination of monosodium urate crystals in the synovial fluid remains the gold standard for the diagnosis of gout. On ultra-sound (US) examination, the double contour sign (DCS) is one of the most common imaging findings of gout.
Serdar Kokar, Özlem Mercan, Kenan Akgün   +2 more
doaj   +1 more source

Neutrophil autophagy induced by monosodium urate crystals facilitates neutrophil extracellular traps formation and inflammation remission in gouty arthritis. [PDF]

Front Endocrinol (Lausanne), 2023
Huang S, Wang Y, Lin S, Guan W, Liang H, Shen J.   +5 more
europepmc   +1 more source

A wild rice-derived peptide R14 ameliorates monosodium urate crystals-induced IL-1β secretion through inhibition of NF-κB signaling and NLRP3 inflammasome activation. [PDF]

PeerJ, 2023
Charoenwutthikun S, Chanjitwiriya K, Roytrakul S, Kunthalert D.   +3 more
europepmc   +1 more source

Uricase-Deficient Larval Zebrafish with Elevated Urate Levels Demonstrate Suppressed Acute Inflammatory Response to Monosodium Urate Crystals and Prolonged Crystal Persistence. [PDF]

Genes (Basel), 2022
Linnerz T, Sung YJ, Rolland L, Astin JW, Dalbeth N, Hall CJ.   +5 more
europepmc   +1 more source

Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response. [PDF]

Cell Rep, 2022
Cobo I, Cheng A, Murillo-Saich J, Coras R, Torres A, Abe Y, Lana AJ, Schlachetzki J, Liu-Bryan R, Terkeltaub R, Sanchez-Lopez E, Glass CK, Guma M.   +12 more
europepmc   +1 more source

microRNA-223 Deficiency Exacerbates Acute Inflammatory Response to Monosodium Urate Crystals by Targeting NLRP3. [PDF]

J Inflamm Res, 2021
Yang QB, Li LQ, Zhang QB, He YL, Mi QS, Zhou JG.   +5 more
europepmc   +1 more source

Severe Carpal Tunnel Syndrome Caused by Gouty Tophi Diagnosed by Dual Energy Computed Tomography: Case Report

The Turkish Journal of Gastroenterology, 2016
Gout is a common form of inflammatory arthritis, and the majority of gout patients experience recurrent acute attacks, joint damage, and other complications.
Yan GE, Fen LI, Jinwei CHEN, Jing TIAN
doaj  

GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells

Scientific Reports
Gout is a common autoinflammatory joint diseases characterized by deposition of monosodium urate (MSU) crystals which trigger an innate immune response mediated by inflammatory cytokines.
Orsolya I. Gaal, Ruiqi Liu, Dragoș Marginean, Medeea Badii, Georgiana Cabău, Ioana Hotea, Valentin Nica, Doina Colcear, HINT Consortium, Cristina Pamfil, Tony R. Merriman, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten   +14 more
doaj   +1 more source

Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging. [PDF]

Sci Rep, 2022
Accart N, Dawson J, Obrecht M, Lambert C, Flueckiger M, Kreider J, Hatakeyama S, Richards PJ, Beckmann N.   +8 more
europepmc   +1 more source

Virtual noncontrast images reveal gouty tophi in contrast-enhanced dual-energy CT: a phantom study

European Radiology Experimental
Background Dual-energy computed tomography (DECT) is useful for detecting gouty tophi. While iodinated contrast media (ICM) might enhance the detection of monosodium urate crystals (MSU), higher iodine concentrations hamper their detection.
Karim Khayata, Torsten Diekhoff, Jürgen Mews, Sydney Schmolke, Maximilian Kotlyarov   +4 more
doaj   +1 more source