Results 201 to 210 of about 107,366 (301)

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, Volume 13, Issue 35, 24 June 2026.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Monounsaturated Fatty Acids in Cardiovascular Disease: Intake, Individual Types, and Content in Adipose Tissue as a Biomarker of Endogenous Exposure. [PDF]

Nutrients
Pedersen J, Hedegaard BS, Schmidt EB, Dahm CC, Holven KB, Retterstøl K, Calder PC, Bork C.   +7 more
europepmc   +1 more source

NSUN5 Attenuates Renal Injury and Ferroptosis in Hyperuricaemic Nephropathy Through YBX2‐Dependent Stabilisation of SCD1 m5C Methylation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
NSUN5 is downregulated in hyperuricaemic nephropathy. Overexpression of NSUN5 enhances the stability of SCD1 mRNA through the m5C reader YBX2, ultimately inhibiting ferroptosis in renal tubular epithelial cells. Additionally, this axis suppresses the NF‐κB signaling pathway to alleviate inflammation and upregulates ABCG2 to promote uric acid excretion,
Xiu‐xiu Song, Xiao‐guo Suo, Yue Yu, Kuo Zhang, Chen‐ao Li, Jie Wang, Hui‐xia Xu, Si‐yu Niu, Dong‐xue Lv, Zi‐hao He, Feng‐he Li, Xiao‐ming Meng, Juan Jin   +12 more
wiley   +1 more source

Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3. [PDF]

Cell Death Dis
Cao Y, Li J, Chen Y, Wang Y, Liu Z, Huang L, Liu B, Feng Y, Yao S, Zhou L, Yin Y, Huang Z.   +11 more
europepmc   +1 more source

Differential Effects of Ruminant and Industrial 18-Carbon trans-Monounsaturated Fatty Acids (trans Vaccenic and Elaidic) on the Inflammatory Responses of an Endothelial Cell Line. [PDF]

Molecules, 2021
Valenzuela CA, Baker EJ, De Souza CO, Miles EA, Calder PC.   +4 more
europepmc   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, Volume 13, Issue 33, 15 June 2026.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Causal Association Between Monounsaturated Fatty Acids and Lung Cancer: A Two-Sample Mendelian Randomization Study. [PDF]

Clin Respir J
Zhang S, Jiang J, Wu X, Liu J, Lei W, Chen S, Zeng Y, Liu X, Xiao Q.   +8 more
europepmc   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, Volume 13, Issue 34, 19 June 2026.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Deciphering the role of oleic acid in diabetic retinopathy: an empirical analysis of monounsaturated fatty acids. [PDF]

Nutr Metab (Lond)
Wang Z, Wang H, Chen Y, Chen Y, Zhang X, Diwon A, Zhang G, Sheng Q, Mei H, Xu Y, Zhang X, Mao Q, Zheng C, Mao G.   +13 more
europepmc   +1 more source

Impact of Varying Soybean Oil Concentrations on the Cytokine Profile of Skeletal Muscle and Liver of Pigs: A Systems Biology Approach

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Lipids are important for metabolic processes, mainly cytokine regulation in the skeletal muscle and liver. Considering the soybean oil concentration, a weighted gene co‐expression network analysis (WGCNA) was used to perform an integrative analysis in skeletal muscle and liver tissues.
Fernanda Nery Ciconello, Julia Dezen Gomes, Simara Larissa Fanalli, Bárbara Silva‐Vignato, Andrezza Maria Felício‐Ament, Vivian Vezzoni de Almeida, Cristina Tchorny Moncau‐Gadbem, James Eugene Koltes, Christopher Keith Tuggle, Aline Silva Mello Cesar   +9 more
wiley   +1 more source