Results 21 to 30 of about 22,920 (247)

Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma [PDF]

open access: yes, 2011
Asthma patients who continue to experience symptoms despite being on regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered ...
Adams   +207 more
core   +1 more source

Montelukast promotes mitochondrial biogenesis via CREB/PGC-1α in human bronchial epithelial cells

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Bronchial epithelial mitochondrial dysfunction including impaired mitochondrial biogenesis has been linked with the initiation and development of bronchial asthma.
Huan Wang   +4 more
doaj   +1 more source

Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats. [PDF]

open access: yes, 2003
Increased activation of alveolar macrophage, neutrophil and mast cell has been proven in cigarette smoking (CS)-related lung disorders (CSLD). An increased production of cysteinyl-leukotrienes (LTs), which are mediators secreted from the mentioned cells,
Coskun, Senol   +3 more
core   +1 more source

The effect of montelukast on depression behavior in rat forced swimming test

open access: yesPsychiatry and Behavioral Sciences, 2017
Objective: Montelukast (brand name: Singulair), which is used for treatment of chronic asthma, is a leukotriene receptor antagonist. The psychiatric side effects of montelukast use in asthma patients are controversial. The aim of this study is to examine
Ersoz Gonca
doaj   +1 more source

The examination of the nephroprotective effect of montelukast sodium and N-acetylcysteine ın renal ıschemia with dimercaptosuccinic acid imaging in a placebo-controlled rat model [PDF]

open access: yesActa Cirúrgica Brasileira, 2020
Purpose To determine the nephroprotective effect of NAC and Montelukast Sodium administration against the development of renal damage associated with long warm renal ischemia.
Arif Aydin   +9 more
doaj   +1 more source

Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]

open access: yes, 2019
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna)   +1 more
core   +4 more sources

Integrating evidence for managing asthma in patients who smoke [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Bjermer, Leif   +3 more
core   +1 more source

Gastroprotective and Antioxidant Effects of Montelukast on Indomethacin-Induced Gastric Ulcer in Rats

open access: yesJournal of Pharmacological Sciences, 2007
Montelukast, a selective reversible cysteinyl leukotriene D4-receptor (LTD4 receptor) antagonist, is used in the treatment of asthma. We have investigated alterations in the glutathione (GSH) and activity levels of antioxidative enzymes [superoxide ...
Gunnur Ozbakis Dengiz   +4 more
doaj   +1 more source

Sleeptalking! Sleepwalking! Side Effects of Montelukast

open access: yesCase Reports in Pulmonology, 2013
A 16-year-old Caucasian female presented to the pulmonary clinic for a followup on her asthma. Due to the worsening of allergy-related symptoms, therapy with montelukast 10 mg daily was started and resulted in good relief of the patient’s symptoms.
Samer Alkhuja   +2 more
doaj   +1 more source

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