Results 41 to 50 of about 3,766,461 (388)

Non-randomised feasibility study of training workshops for Talking Therapies service high-intensity therapists to optimise depression and anxiety outcomes for individuals with co-morbid personality difficulties: a study protocol

open access: yesPilot and Feasibility Studies, 2023
Background The NHS Talking Therapies for Anxiety and Depression programme (‘TTad’; formerly Improving Access to Psychological Therapies ‘IAPT’) delivers high-intensity cognitive behavioural therapy (CBT) to over 200,000 individuals each year for common ...
Laura A. Warbrick   +13 more
doaj   +1 more source

Manic patients and sleep management: the role of polysomnography in clinical practice

open access: yesEuropean Psychiatry, 2022
Introduction Sleep plays a key role in the pathogenesis and clinic of mood disorders. However, few studies have investigated electroencephalographic sleep parameters during the manic phases of Bipolar Disorder (BD).
F. Pacchioni   +6 more
doaj   +1 more source

Current Understanding of Gut Microbiota in Mood Disorders: An Update of Human Studies

open access: yesFrontiers in Genetics, 2019
Gut microbiota plays an important role in the bidirectional communication between the gut and the central nervous system. Mounting evidence suggests that gut microbiota can influence the brain function via neuroimmune and neuroendocrine pathways as well ...
Ting-ting Huang   +5 more
semanticscholar   +1 more source

Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD:implication for COPD-associated neuropathogenesis [PDF]

open access: yes, 2014
The circadian timing system controls daily rhythms of physiology and behavior, and disruption of clock function can trigger stressful life events. Daily exposure to cigarette smoke (CS) can lead to alteration in diverse biological and physiological ...
A Agusti   +79 more
core   +2 more sources

Mood Prediction of Patients With Mood Disorders by Machine Learning Using Passive Digital Phenotypes Based on the Circadian Rhythm: Prospective Observational Cohort Study

open access: yesJournal of Medical Internet Research, 2019
Background Virtually, all organisms on Earth have their own circadian rhythm, and humans are no exception. Circadian rhythms are associated with various human states, especially mood disorders, and disturbance of the circadian rhythm is known to be very ...
C. Cho   +5 more
semanticscholar   +1 more source

Safety of 80 antidepressants, antipsychotics, anti‐attention‐deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta‐review of 78 adverse effects

open access: yesWorld Psychiatry, 2020
Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental disorders in this age group and are used not infrequently off‐label.
M. Solmi   +8 more
semanticscholar   +1 more source

Impact of SARS-CoV-2 Infection on Cognitive Function: A Systematic Review

open access: yesFrontiers in Psychiatry, 2021
The prevalence and etiology of COVID-19's impact on brain health and cognitive function is poorly characterized. With mounting reports of delirium, systemic inflammation, and evidence of neurotropism, a statement on cognitive impairment among COVID-19 ...
Yazen Alnefeesi   +16 more
doaj   +1 more source

Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder [PDF]

open access: yes, 2011
Hyperpolarization activated cyclic nucleotide-gated (HCN) potassium channels are implicated in the control of neuronal excitability and are expressed widely in the brain. HCN4 is expressed in brain regions relevant to mood and anxiety disorders including
Abbas   +66 more
core   +1 more source

The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders

open access: yesFrontiers in Neurology, 2019
The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis.
Yang Jin   +4 more
semanticscholar   +1 more source

The key role of insomnia and sleep loss in the dysregulation of multiple systems involved in mood disorders: A proposed model

open access: yesJournal of Sleep Research, 2019
Mood disorders are amongst the most prevalent and severe disorders worldwide, with a tendency to be recurrent and disabling. Although multiple mechanisms have been hypothesized to be involved in their pathogenesis, just a few integrative theoretical ...
L. Palagini   +4 more
semanticscholar   +1 more source

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