Results 41 to 50 of about 683,455 (344)

Serotonin and corticosterone rhythms in mice exposed to cigarette smoke and in patients with COPD:implication for COPD-associated neuropathogenesis [PDF]

, 2014
The circadian timing system controls daily rhythms of physiology and behavior, and disruption of clock function can trigger stressful life events. Daily exposure to cigarette smoke (CS) can lead to alteration in diverse biological and physiological ...
A Agusti, A Hida, A Mykletun, A Papi, A Thomas, C Laurin, CJ Murray, CJ Rosen, CL Tsai, CM Ciarleglio, CM Kim, CM Spengler, DA Lewis, E Repapi, EJ Wagena, EJ Wagena, Elizabeth Lyda, F Di Marco, Firoze Khan, FM Botelho, FW Turek, G Cavadini, GE Tafet, GJ Borsboom, GV Carr, H Bando, H Chen, H Chen, H Chen, H Chen, H Hadden, H Yao, H Yao, H Yao, HC Atkinson, Hongwei Yao, I Rahman, I Wilson, Irfan Rahman, Isaac K. Sundar, J Liu, JA Mohawk, JE Gibbs, JL Malisch, JM Gierisch, JM Launay, JM Murphy, JS Takahashi, JW Hwang, K Lutfy, KA Lamia, KF Rabe, LE Kalynchuk, M Ishikawa, Michael T. Sellix, MW Zhang, NA Hanania, OP Soldin, P Dome, Patricia J. Sime, PD Altland, PJ Barnes, PJ Sollars, RA Prosser, RY Moore, S Eddahibi, S Gebel, SA Antoniu, SH Yoo, SK Droste, T Ishii, T Sekiduka-Kumano, U Albrecht, W Stinn, WB Essman, WK Lau, WK Lau, WT McNicholas, Y Ban, Yadi Huang   +79 more
core   +2 more sources

Impact of SARS-CoV-2 Infection on Cognitive Function: A Systematic Review

Frontiers in Psychiatry, 2021
The prevalence and etiology of COVID-19's impact on brain health and cognitive function is poorly characterized. With mounting reports of delirium, systemic inflammation, and evidence of neurotropism, a statement on cognitive impairment among COVID-19 ...
Yazen Alnefeesi, Ashley Siegel, Leanna M. W. Lui, Kayla M. Teopiz, Roger C. M. Ho, Yena Lee, Flora Nasri, Hartej Gill, Kangguang Lin, Kangguang Lin, Bing Cao, Joshua D. Rosenblat, Joshua D. Rosenblat, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre   +16 more
doaj   +1 more source

The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders [PDF]

, 2018
Major mood disorders, which primarily include bipolar disorder and major depressive disorder, are the leading cause of disability worldwide and pose a major challenge in identifying robust risk genes.
A Hayashi-Takagi, A Heinz, A J Forstner, A Meyer-Lindenberg, A Okbay, A Okbay, A Reif, A Stuhrmann, AB Niculescu, AB Niculescu, AH Fanous, AR Hariri, AR Hariri, AR Hariri, AV Kravitz, B Chih, B Dean, B Li, B Müller-Myhsok, BD Angst, BF Voight, C Colantuoni, C Esslinger, C M Hultman, C M van Duijn, C Sudlow, C Trapnell, C Zhang, CA Rietveld, Converge consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, D Kim, D-d Wu, DM Ruderfer, DP Hibar, E Castelao, FJ McMahon, FS Goes, GB Ehret, GT Konopaske, GTEx Consortium, H Cao, H Cao, H Cao, H Chang, H Kober, H Li, H Tost, H Walter, H Walter, HA Nasrallah, HM Chen, HP Blumberg, I Dudanova, IP Blair, J Hecker, J Strohmaier, JR Almeida, K Amunts, KM Harris, KM Weiss, M Grigoroiu-Serbanescu, M Landén, M Li, M Li, M Li, M Li, M Li, M M Nöthen, M Maletic-Savatic, M Matsuzaki, M Pessiglione, M Preisig, M Rietschel, MA Ferreira, MH de Moor, ML Phillips, N Akula, N Amin, N Amin, N G Martin, N Gaspard, N Grarup, N Hoshina, N Hoshina, N Tzourio-Mazoyer, P B Mitchell, P Costa, P McGuffin, P Penzes, P R Schofield, PJ Harrison, Psychiatric Genomics Consortium Bipolar Disorder Working Group, R Kotov, RA Poldrack, RJ Pruim, RS Duman, S Cichon, S Cichon, S Durnaoglu, S E Bergen, S Erk, S Erk, S Hayashi, S Kruger, S Ripke, SB Eickhoff, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SM Purcell, T G Schulze, T Yagi, T Yamamoto, TB Ustun, TM Frayling, TT Chu, TW Muhleisen, X Xiao, X Zhu, Y Kong, Y Ma, Y Ma, Y Wang, Z Kutalik   +122 more
core   +8 more sources

Institutional Compassion in Student Transition to University: Findings from the Nurture-U Compassionate Campus Project

Education Sciences
Compassionate university practices can increase students’ sense of belonging and lead to higher wellbeing. This study presents qualitative data from a UK university collected as part of the Nurture-U Compassionate Campus project.
Jemima Dooley, Vanessa Forbes, Amelia Green, Pranati Misurya, Polly Card, Felicity Thomas, Ed Watkins, Louise Lawrence   +7 more
doaj   +1 more source

An investigation of cannabis use for insomnia in depression and anxiety in a naturalistic sample

BMC Psychiatry, 2022
Background Little is known about cannabis use for insomnia in individuals with depression, anxiety, and comorbid depression and anxiety. To develop a better understanding of distinct profiles of cannabis use for insomnia management, a retrospective ...
Nirushi Kuhathasan, Luciano Minuzzi, James MacKillop, Benicio N. Frey   +3 more
doaj   +1 more source

Mood Disorders and Gluten: It’s Not All in Your Mind! A Systematic Review with Meta-Analysis [PDF]

, 2018
Gluten elimination may represent an effective treatment strategy for mood disorders in individuals with gluten-related disorders. However, the directionality of the relationship remains unclear. We performed a systematic review of prospective studies for
Bold, Justine, Busby, E., Fellows, Lindsey, Rostami, K.   +3 more
core   +3 more sources

Pathological Skin Picking: Case Presentation and Review of the Literature [PDF]

, 2015
Pathological skin picking is a condition in which patients induce skin lesions through repetitive, compulsive excoriations of normal skin or skin with minor surface irregularities and they admit their role in the production of the lesions, but are unable
Benea, Vasile, Georgescu, Simona Roxana, Leahu, Diana, Raileanu, Cristina, Sarbu, Maria Isabela, Tampa, Mircea   +5 more
core   +3 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

The Efficacy of Vortioxetine on Anhedonia in Patients With Major Depressive Disorder

Frontiers in Psychiatry, 2019
Background: Anhedonia is a common, persistent, and disabling phenomenon in treated adults with Major Depressive Disorder (MDD). Hitherto, relatively few antidepressant agents have been evaluated with respect to their effect on anhedonia in MDD.Methods ...
Bing Cao, Bing Cao, Caroline Park, Caroline Park, Mehala Subramaniapillai, Yena Lee, Yena Lee, Michelle Iacobucci, Rodrigo B. Mansur, Hannah Zuckerman, Lee Phan, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre, Roger S. McIntyre   +14 more
doaj   +1 more source

NMDA receptor inhibition prevents intracellular sodium elevations in human olfactory neuroepithelial precursors derived from bipolar patients

Scientific Reports, 2022
Dysregulation of ion flux across membranes and glutamate-induced excitotoxicity appear to be important pathophysiologic abnormalities in bipolar illness. Understanding ion control and responses to ionic stress is important to decipher the pathogenesis of
Yonglin Gao, Aaron A. Mack, Carleigh Litteral, Nicholas A. Delamere, Rif S. El-Mallakh   +4 more
doaj   +1 more source