Bioinformatics and moonlighting proteins [PDF]
Frontiers in Bioengineering and Biotechnology, 2015 Multitasking or moonlighting is the capability of some proteins to execute two or more biochemical functions. Usually, moonlighting proteins are experimentally revealed by serendipity.
Sergio eHernández +8 more
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Moonlighting Proteins at the Candidal Cell Surface [PDF]
Microorganisms, 2020 The cell wall in Candida albicans is not only a tight protective envelope but also a point of contact with the human host that provides a dynamic response to the constantly changing environment in infection niches.
Dorota Satala +4 more
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Gene duplication and the evolution of moonlighting proteins [PDF]
Frontiers in Genetics, 2015 Gene duplication is a recurring phenomenon in genome evolution and a major driving force in the gain of biological functions. Here, we examine the role of gene duplication in the origin and maintenance of moonlighting proteins, with special focus on ...
Adriana eEspinosa-Cantú +3 more
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Moonlighting proteins in cancer. [PDF]
Cancer Lett, 2016 Since the 1980s, growing evidence suggested that the cellular localization of proteins determined their activity and biological functions. In a classical view, a protein is characterized by the single cellular compartment where it primarily resides and functions. It is now believed that when proteins appear in different subcellular locations, the cells
Min KW, Lee SH, Baek SJ.
europepmc +5 more sources
Dancing to Another Tune—Adhesive Moonlighting Proteins in Bacteria
Biology, 2014 Biological moonlighting refers to proteins which express more than one function. Moonlighting proteins occur in pathogenic and commensal as well as in Gram-positive and Gram-negative bacteria.
Veera Kainulainen, Timo K. Korhonen
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BACTERIAL MOONLIGHTING PROTEINS [PDF]
Postępy Mikrobiologii, 2017 Abstract Existence of moonlighting proteins in microorganisms is a known phenomenon, yet still not well understood. Moonlighting proteins have at least two independent biological functions, which must be performed by one polypeptide chain without separation into protein domains.
Jagoda Płaczkiewicz
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MoonProt 3.0: an update of the moonlighting proteins database. [PDF]
Nucleic Acids Res, 2021 Chen C +16 more
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Moonlighting Proteins and Their Role in the Control of Signaling Microenvironments, as Exemplified by cGMP and Phytosulfokine Receptor 1 (PSKR1) [PDF]
Frontiers in Plant Science, 2018 Signal generating and processing complexes and changes in concentrations of messenger molecules such as calcium ions and cyclic nucleotides develop gradients that have critical roles in relaying messages within cells.
Helen R. Irving +3 more
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Moonlighting proteins are variably exposed at the cell surfaces of Candida glabrata, Candida parapsilosis and Candida tropicalis under certain growth conditions [PDF]
BMC Microbiology, 2019 Background Adaptability to different environmental conditions is an essential characteristic of pathogenic microorganisms as it facilitates their invasion of host organisms.
Justyna Karkowska-Kuleta +4 more
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Rhamnose Links Moonlighting Proteins to Membrane Phospholipid in Mycoplasmas. [PDF]
PLoS ONE, 2016 Many proteins that have a primary function as a cytoplasmic protein are known to have the ability to moonlight on the surface of nearly all organisms. An example is the glycolytic enzyme enolase, which can be found on the surface of many types of cells ...
James M Daubenspeck +2 more
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