Results 21 to 30 of about 5,705 (144)

MultitaskProtDB-II: an update of a database of multitasking/moonlighting proteins. [PDF]

open access: yesNucleic Acids Res, 2018
Franco-Serrano L   +11 more
europepmc   +2 more sources

Physical Features of Intracellular Proteins that Moonlight on the Cell Surface. [PDF]

open access: yesPLoS ONE, 2015
Moonlighting proteins comprise a subset of multifunctional proteins that perform two or more biochemical functions that are not due to gene fusions, multiple splice variants, proteolytic fragments, or promiscuous enzyme activities.
Vaishak Amblee, Constance J Jeffery
doaj   +1 more source

Moonlighting Proteins in Yeasts [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2008
SUMMARY Proteins able to participate in unrelated biological processes have been grouped under the generic name of moonlighting proteins. Work with different yeast species has uncovered a great number of moonlighting proteins and shown their importance for adequate functioning of the yeast cell.
Gancedo, Carlos, Flores, Carmen-Lisset
openaire   +3 more sources

Integrins: Moonlighting Proteins in Invadosome Formation. [PDF]

open access: yesCancers (Basel), 2019
Invadopodia are actin-rich protrusions developed by transformed cells in 2D/3D environments that are implicated in extracellular matrix (ECM) remodeling and degradation. These structures have an undoubted association with cancer invasion and metastasis because invadopodium formation in vivo is a key step for intra/extravasation of tumor cells ...
Peláez R   +3 more
europepmc   +6 more sources

Moonlighting peptides with emerging function. [PDF]

open access: yesPLoS ONE, 2012
Hunter-killer peptides combine two activities in a single polypeptide that work in an independent fashion like many other multi-functional, multi-domain proteins.
Jonathan G Rodríguez Plaza   +15 more
doaj   +1 more source

Computational characterization of moonlighting proteins. [PDF]

open access: yesBiochem Soc Trans, 2014
Moonlighting proteins perform multiple independent cellular functions within one polypeptide chain. Moonlighting proteins switch functions depending on various factors including the cell-type in which they are expressed, cellular location, oligomerization status and the binding of different ligands at different sites.
Khan IK, Kihara D.
europepmc   +4 more sources

Moonlighting in Mitosis: Analysis of the Mitotic Functions of Transcription and Splicing Factors

open access: yesCells, 2020
Moonlighting proteins can perform one or more additional functions besides their primary role. It has been posited that a protein can acquire a moonlighting function through a gradual evolutionary process, which is favored when the primary and secondary ...
Maria Patrizia Somma   +8 more
doaj   +1 more source

Moonlighting proteins - an approach to systematize the concept. [PDF]

open access: yesIn Silico Biol, 2020
Moonlighting refers to a protein with at least two unrelated, mechanistically different functions. As a concept, moonlighting describes a large and diverse group of proteins which have been discovered in a multitude of organisms. As of today, a systematized view on these proteins is missing. Here, we propose a classification of moonlighting proteins by
Krantz M, Klipp E.
europepmc   +4 more sources

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