Results 151 to 160 of about 1,649 (211)

The delta opioid receptor agonist KNT-127 relieves innate anxiety-like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala. [PDF]

Neuropsychopharmacol Rep
Kawaminami A, Yamada D, Yoshioka T, Hatakeyama A, Nishida M, Kajino K, Saitoh T, Nagase H, Saitoh A.   +8 more
europepmc   +1 more source

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase

, 2019
Qian Li, Zongli Xu, Wei Zhang, Belinda Wilson, Jau‐Shyong Hong, Patrick M. Flood   +5 more
openalex   +1 more source

Uncovering the molecular basis of high morphinan product efficiency in opium poppy through Multi-omics integrated analysis with multi-capsules [PDF]

Yumin Huang, Mao Sun, Wuhu Gong, Yifeng Liu, Yimeng Cheng, Lijuan Yuan, Yuanming Wu   +6 more
openalex   +1 more source

Semi-synthesis in the exploration of opioid-targeting natural products.

Nat Prod Rep
Riley AP.
europepmc   +1 more source

Do CYP2D6 genotypes affect oxycodone dose, pharmacokinetics, pain, and adverse effects in cancer? [PDF]

Pharmacogenomics
Wong AK, Vogrin S, Klepstad P, Rubio J, Le B, Philip J, Somogyi AA.   +6 more
europepmc   +1 more source

Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor. [PDF]

Nat Commun
Suno-Ikeda C, Nishikawa R, Suzuki R, Yokoi S, Iwata S, Takai T, Ogura T, Hirose M, Tokuda A, Katamoto R, Inoue A, Asai E, Kise R, Sugita Y, Kato T, Nagase H, Mitsutake A, Saitoh T, Katayama K, Inoue A, Kandori H, Kobayashi T, Suno R.   +22 more
europepmc   +1 more source

Bone protective effect of sinomenine against monosodium iodoacetate induced knee and hip injury in rat model: an inflammatory pathway. [PDF]

Acta Cir Bras
Lei YH, Hu XX, Wen HJ, Deng YC, Jiang JL, Zhao QG.   +5 more
europepmc   +1 more source

Structure–Signal Relationships of the <i>δ</i>-Opioid-Receptor (DOR)-Selective Agonist KNT-127—Part I: Impact of the Morphinan Skeleton on the G-Protein-Biased DOR Agonism

Keita Kajino, Tomoya Sugai, Ryoji Kise, Riko Suzuki, Akihisa Tokuda, Yuki Sekiya, Tomoya Kakumoto, Risako Katamoto, Noriki Kutsumura, Yasuyuki Nagumo, Asuka Inoue, Tsuyoshi Saitoh   +11 more
openalex   +2 more sources

Transcriptome Analysis of <i>Stephania yunnanensis</i> and Functional Validation of CYP80s Involved in Benzylisoquinoline Alkaloid Biosynthesis. [PDF]

Molecules
Shi W, Li Q, Li X, Luo L, Gan J, Ma Y, Wang J, Chen T, Chen T, Zhang Y, Su P, Ma X, Guo J, Huang L.   +13 more
europepmc   +1 more source

Evaluation Of Novel Ligands For Opioid Receptors [PDF]

, 2015
Tarawneh, Amer Hussien
core   +1 more source