Results 191 to 200 of about 270,592 (355)

TLR7 Mediates HIV‐1 Tat‐Induced Cellular Senescence in Human Astrocytes

open access: yesAging Cell, EarlyView.
Once internalized into endolysosomes, HIV‐1 Tat interacts and activates TLR7, causing endolysosome damage. Such interaction between HIV‐1 Tat and TLR7 also leads to a senescence‐like phenotype in astrocytes, including cell cycle arrest, elevated levels of p21 and p16 proteins, increased SA‐β‐gal activity, and enhanced secretion of SASP factors ...
Neda Rezagholizadeh   +5 more
wiley   +1 more source

Comparison of the analgesic dose of intravenous ketamine versus ketorolac in patients with chest trauma: A randomized double‐blind clinical trial

open access: yesAcademic Emergency Medicine, Volume 32, Issue 4, Page 426-433, April 2025.
Abstract Background Pain management is a critical part of treatment in patients with chest trauma. Opioids and nonsteroidal anti‐inflammatory drugs have been the most commonly used medications. However, their side effects have drawn attention to other medications.
Hossein Zabihi Mahmoodabadi   +4 more
wiley   +1 more source

The Fruit Essential oil of Cuminum cyminum L. Reduced the Acquisition but not Expression of Ineffective dose of Morphine-Induced Conditioned Place Preference in Morphine- Sensitized Mice

open access: yesJournal of Medicinal Plants, 2009
Background: Cuminum cyminum fruit essential oil (FEO) dose-dependently can attenuate the expression of morphine tolerance and dependence in morphine-dependent mice.
A Haghparast   +4 more
doaj  

EFFECTS OF ANXIETY AND MORPHINE ON DISCRIMINATION OF INTENSITIES OF PAINFUL STIMULI [PDF]

open access: bronze, 1952
Harris E. Hill   +3 more
openalex   +1 more source

Emergency department–initiated oral naltrexone for patients with moderate to severe alcohol use disorder: A pilot feasibility study

open access: yesAcademic Emergency Medicine, Volume 32, Issue 5, Page 488-497, May 2025.
Abstract Objectives Alcohol use disorder (AUD) is the most common substance use disorder in the United States. Despite availability of four FDA‐approved medications, fewer than 10% of patients are prescribed medication. This study aimed to evaluate the impact and feasibility of emergency department (ED)‐initiated oral naltrexone in patients with ...
Ethan Cowan   +6 more
wiley   +1 more source

Research Note: Morphine influences circulating and tissue concentrations of met-enkephalin and proenkephalin (PENK) expression and plasma concentrations of corticosterone in chickens

open access: yesPoultry Science
: The effects of the administration of the opioid agonist, morphine, on plasma and tissue concentrations of Met-enkephalin were determined in 14 wk old female chickens.
Colin G. Scanes   +1 more
doaj  

Effects of Estrogen Receptor Modulators on Morphine Induced Sensitization in Mice Memory

open access: yesIranian Journal of Psychiatry, 2016
Objective: In this study, the effects of estradiol valerate and raloxifenea selective estrogen receptor modulator; (SERM) on morphine induced sensitization were examined in mice memory, according to the step-down passive avoidance task.
Mahdieh Anoush   +3 more
doaj  

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