Results 191 to 200 of about 397,909 (400)

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

Novel LncRNA Gm44763 Regulates Morphine-Induced Reward Memory via MiR-298-5p-Mediated eIF4E Translation Control. [PDF]

open access: yesResearch (Wash D C)
Gao F   +13 more
europepmc   +1 more source

Needle tenoscopy of the digital flexor tendon sheath in four horses

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Tenoscopy, performed under general anaesthesia (GA), remains the gold standard diagnostic modality for assessment of the digital flexor tendon sheath (DFTS). A cadaver study described needle tenoscopy of the DFTS in a standing horse model, but the procedure has not been reported in clinical cases.
L. J. Breen   +4 more
wiley   +1 more source

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

open access: yesEquine Veterinary Education, EarlyView.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch   +4 more
wiley   +1 more source

Efficacy of morphine on cough in patients with repeat expansions of <i>RFC1</i> and refractory chronic cough. [PDF]

open access: yesERJ Open Res
Guilleminault L   +5 more
europepmc   +1 more source

Ameliorating Effects of Honey on Ethanol, Caffeine, Morphine and Scopolamine- Novelty Induced Behaviors and Memory Impairment in Male Albino Mice

open access: diamond
Ayodele Oluwasoji Akanmu   +6 more
openalex   +2 more sources

Intraoperative Ketamine and Chronic Opioid Use: Less Pain, More Morphine? [PDF]

open access: bronze, 2011
Randy W. Loftus   +2 more
openalex   +1 more source

Management of a diaphragmatic hernia using self‐locking knots

open access: yesEquine Veterinary Education, EarlyView.
Summary A 4‐year‐old Thoroughbred gelding was presented with a history of severe colic signs that were non‐responsive to non‐steroidal anti‐inflammatory drugs. During initial evaluation, distended small intestine was observed, together with continued colic signs and a serosanguinous abdominocentesis sample.
A. Gillen   +4 more
wiley   +1 more source

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