Results 41 to 50 of about 168,528 (214)
Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia
Frontiers in Neuroscience, 2019 The use of morphine, the standard opioid drug, is limited by its undesirable effects, such as tolerance, physical dependence, and hyperalgesia (increased pain sensitivity).
Bárbara Guimaraes de Freitas +6 more
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Poultry Science: The effects of the administration of the opioid agonist, morphine, on plasma and tissue concentrations of Met-enkephalin were determined in 14 wk old female chickens.
Colin G. Scanes +1 more
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Characterization of a Single Chain Fv Antibody that Reacts with Free Morphine
Antibodies, 2013 An immune phage library derived from mice, hyperimmunized with morphine-conjugated BSA, was used to isolate a single-chain Fv (scFv) clone, M86, with binding activity to morphine-conjugated thyroglobulin (morphine-C-Tg) but not to codeine-, cocaine-, or ...
Kazuhisa Sugimura +6 more
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Assessment of a von Frey device for evaluation of the antinociceptive effects of morphine and its application in pharmacodynamic modeling of morphine in dogs [PDF]
, 2005 Butch KuKanich +2 more
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Effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference in mice [PDF]
Avicenna Journal of Phytomedicine, 2011 Objective: In the present study, the effects of aqueous saffron extract (Crocus sativus L.) on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice were investigated.
Hossein Hosseinzadeh +2 more
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Neural Plasticity, 2009 Chronic morphine administration shifts delta-opioid receptors (DORs) from the cytoplasm to the plasma membrane. Given that microinjection of morphine into the PAG produces antinociception, it is hypothesized that the movement of DORs to the membrane will
Michael M. Morgan +3 more
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Activation of Spinal Anti-analgesic System Following Electroacupuncture Stimulation in Rats
Journal of Pharmacological Sciences, 2005 We evaluated the interaction between electroacupuncture (EA)-induced antinociception and an endogenous anti-analgesic system. EA was applied to the ST-36 acupoint for 45 min in male Sprague-Dawley rats, and pain thresholds were assessed by the hind-paw ...
Yohji Fukazawa +7 more
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Microglia in morphine tolerance: cellular and molecular mechanisms and therapeutic potential
Frontiers in PharmacologyMorphine has a crucial role in treating both moderate to severe pain and chronic pain. However, prolonged administration of morphine can lead to tolerance of analgesia, resulting in increased doses and poor treatment of pain. Many patients, such as those
Xiangning Zhang +9 more
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Effects of Testosterone on Analgesia in Formalin-Treated Mice
Journal of Ardabil University of Medical Sciences, 2018 CT Background & objectives: So far, various reports have been presented on the relationship between sex hormones and gender-related differences in pain and analgesia in humans and laboratory animals.
Akram Alijani +3 more
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