Results 41 to 50 of about 303,149 (361)
On the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation [PDF]
, 2013 The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the Central Nervous System and the peripheral nociceptors has become of increasing interest.
Agnati, Luigi F +6 more
core +3 more sources
Arthritis Care &Research, Accepted Article.Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
M3 muscarinic acetylcholine receptor facilitates the endocytosis of mu opioid receptor mediated by morphine independently of the formation of heteromeric complexes [PDF]
, 2017 Morphine inefficiency to induce the internalization of mu opioid (MOP) receptors observed in numerous experimental models constitutes a paradigm of G-protein coupled receptor (GPCR) functional selectivity.
Alvarez-Curto, Elisa +2 more
core +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Comparison of morphine and morphine with ketamine for postoperative analgesia [PDF]
Canadian Journal of Anaesthesia, 1996 The purpose of this study was to compare morphine with ketamine to morphine alone in a double-blind investigation of postsurgical pain control.Forty-two ASA 1 and 2 patients undergoing elective microdiscectomy were administered either 1 mg.ml-1 of morphine (n = 20) or 1 mg.ml-1 of both morphine and ketamine (n = 22) via iv patient controlled analgesia (
Keith B. Javery +3 more
openaire +3 more sources
Ingested bovine amniotic fluid enhances morphine antinociception in rats [PDF]
, 2000 Ingestion by rats of rat placenta or amniotic fluid enhances opioid-mediated, or partly opioid-mediated, antinociception produced by morphine injection, vaginal or cervical stimulation, late pregnancy, and foot shock.
Corpening, James W. +2 more
core +1 more source
Metal‐Organic Frameworks Facilitating Complexation for Long‐Cycle Zinc‐Bromine Flow Batteries
Advanced Functional Materials, EarlyView.The organic ligands (imidazole and benzimidazole) from the decomposed zinc ZIF‐62 is proposed to further improve the Br2 complexing ability of the mature complexing agent (i.e., N‐methyl‐N‐ethyl pyrrolidinium bromide (MEP) ionic liquid). The synergistic effect between Im/BIm of the decomposed ZIF‐62 toward bromine species and MEP toward bromine species,
Huaiyang Zheng +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self‐administration in rats [PDF]
, 2019 Drug‐reinforced excessive operant responding is one fundamental feature of long-lasting addiction‐like behaviors and relapse in animals. However, the transcriptional regulatory mechanisms responsible for the persistent drug‐specific (not natural rewards)
Duan, Ying +8 more
core +1 more source
Advanced Sensor Research, EarlyView.A foam‐based ELISA (f‐ELISA) platform was developed using chemically modified melamine foam to enable rapid, ultrasensitive, and selective colorimetric detection of fentanyl and norfentanyl. Abstract Rapid and accurate detection of fentanyl in unknown products and aqueous samples can find the unexpected existence of the toxic chemical and assist law ...
Makela Norwood, Bofeng Pan, Gang Sun
wiley +1 more source