Results 51 to 60 of about 339,726 (399)
Brain Reward Circuits in Morphine Addiction
Molecules and Cells, 2016 Morphine is the most potent analgesic for chronic pain, but its clinical use has been limited by the opiate’s innate tendency to produce tolerance, severe withdrawal symptoms and rewarding properties with a high risk of relapse.
Juhwan Kim +4 more
semanticscholar +1 more source
Nutrition in Clinical Practice, Volume 38, Issue 1, Page 129-137, February 2023., 2023 Abstract Background Chronic analgesic use is described in home parenteral nutrition (HPN)–dependent patients, but there are limited data on factors associated with opioid use for noncancerous pain. Methods Patients attending a national UK intestinal failure reference center were divided in two groups according to strong opioid (SO) usage; risk factors ...
Liat Deutsch +7 more
wiley +1 more source
Kernel Phase and Coronagraphy with Automatic Differentiation [PDF]
, 2020 The accumulation of aberrations along the optical path in a telescope produces distortions and speckles in the resulting images, limiting the performance of cameras at high angular resolution. It is important to achieve the highest possible sensitivity to faint sources such as planets, using both hardware and data analysis software.
arxiv +1 more source
Morphine Analgesia Pre-PPCI Is Associated with Prothrombotic State, Reduced Spontaneous Reperfusion and Greater Infarct Size [PDF]
, 2017 Schattauer GmbH Stuttgart.The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated with opiates, which
Farag, Mohamed +5 more
core +1 more source
Metformin reduces morphine tolerance by inhibiting microglial-mediated neuroinflammation
Journal of Neuroinflammation, 2016 BackgroundTolerance seriously impedes the application of morphine in clinical medicine. Thus, it is necessary to investigate the exact mechanisms and efficient treatment.
Yinbing Pan +9 more
semanticscholar +1 more source
Translational Psychiatry, 2022 The present study investigates the possible therapeutic effects of human mesenchymal stem cell-derived secretome on morphine dependence and relapse. This was studied in a new model of chronic voluntary morphine intake in Wistar rats which shows classic ...
María Elena Quintanilla +8 more
doaj +1 more source
Blinded patient preference for morphine compared to placebo in the setting of chronic refractory breathlessness – an exploratory study [PDF]
, 2015 Context Patients’ preference for morphine therapy has received little attention in the setting of chronic refractory breathlessness. However, this is one important factor in considering longer term therapy.
Abernethy, Amy P. +6 more
core +1 more source
Morphine promotes cancer stem cell properties, contributing to chemoresistance in breast cancer
OncoTarget, 2015 Morphine is an opioid analgesic drug commonly used for pain relief in cancer patients. Here, we report that morphine enhances the mammosphere forming capacity and increases the expression of stemness-related transcription factors Oct4, Sox2 and Nanog ...
semanticscholar +1 more source
Research in Pharmaceutical Sciences, 2019 Interaction of morphine and seizure is complex. Mouse brain hippocampal slices were used to estimate how acute and chronic morphine treatment alters the low-magnesium artificial cerebrospinal fluid (LM-ACSF)-induced seizure activity.
Yousef Panahi +6 more
doaj +1 more source
Morphine Promotes Tumor Angiogenesis and Increases Breast Cancer Progression
BioMed Research International, 2015 Morphine is considered a highly potent analgesic agent used to relieve suffering of patients with cancer. Several in vitro and in vivo studies showed that morphine also modulates angiogenesis and regulates tumour cell growth.
S. Bimonte +7 more
semanticscholar +1 more source