Results 51 to 60 of about 303,149 (361)

Morphine Binds Creatine Kinase B and Inhibits Its Activity

Frontiers in Cellular Neuroscience, 2018
Morphine is an analgesic alkaloid used to relieve severe pain, and irreversible binding of morphine to specific unknown proteins has been previously observed.
Ivan Weinsanto, Jinane Mouheiche, Alexis Laux-Biehlmann, Alexis Laux-Biehlmann, François Delalande, Arnaud Marquette, Virginie Chavant, Virginie Chavant, Florian Gabel, Sarah Cianferani, Alexandre Charlet, Marie-Odile Parat, Yannick Goumon, Yannick Goumon   +13 more
doaj   +1 more source

The Effect of Memantine on the Expression of Dopamine Receptors in the Striatum of Male Rats With Morphine Addiction [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2023
Background and Objectives: Studies have indicated that the chronic use of morphine can result in physical and psychological dependence. Morphine dependence is associated with several cellular and molecular alterations in the mesocorticolimbic system, and
Sahar Khalili Samani, Solmaz Khalifeh, Mehdi Vahiddastjerdi, Mandana Hassanzad, Afshin Kheradmand, Farzaneh Nazari Serenjeh   +5 more
doaj  

PREVALENSI KEJADIAN PONV PADA PEMBERIAN MORFIN SEBAGAI ANALGETIK PASCA OPERASI PENDERITA TUMOR PAYUDARA DENGAN ANESTESI UMUM DI RSUP DR. KARIADI SEMARANG [PDF]

, 2015
Background Morphine is the most abundant analgesic which commonly used for post mastectomy’s pain reliever. Altough, it is potentially cause the adverse effect such as nausea and vomiting.
Dwi Jatmiko, Heru, Qudsi, Alfiani Sofia
core  

PolyMorphine provides extended analgesic-like effects in mice with spared nerve injury. [PDF]

, 2017
Morphine is a well-characterized and effective analgesic commonly used to provide pain relief to patients suffering from both acute and chronic pain conditions.
Chen, Renxun, Kolber, Benedict, Lax, Neil C, Leep, Sarah R, Uhrich, Kathryn, Yu, Lei   +5 more
core   +1 more source

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

Advanced Science, EarlyView.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang, Wei Zhou, Marcelo Cypel, Todd L. Demmy, Gal Shafirstein, Guillermo Garza, Emily Gawrys, Joanna Bogusiewicz, Barbara Bojko, Janusz Pawliszyn   +9 more
wiley   +1 more source

Corticosterone Contributes to Context‐Triggered Retrieval of Morphine Withdrawal Memories by Acting on Basolateral Amygdala Neurons Projecting to Nucleus Accumbens Core

Advanced Science, EarlyView.
Context associated with morphine withdrawal elicits an increase in serum corticosterone levels. Corticosterone participates in CTR‐MWM by acting on MR, but not GR, in the BLA. MR in BLA→NAcC neurons mediates CTR‐MWM. MR increases presynaptic glutamate release and meanwhile participates in D1 receptor‐induced increases in presynaptic glutamate release ...
Zixuan Cao, Yaxian Wen, Yuanqi Chen, Yali Fu, Hao Yang, Chenshan Chu, Xinli Guo, Yu Yuan, Chao Lei, Huan Sheng, Da Shao, Li Yang, Dongyang Cui, Ming Chen, Bin Lai, Ping Zheng   +15 more
wiley   +1 more source

Influence of Nitric Oxide in the Central Amygdala on the Acquisition and Expression of Morphine-Induced Place Preference in Morphine Sensitized Rats

Basic and Clinical Neuroscience, 2011
Effects of intra-central amygdala administration of L-arginine, a nitric oxide precursor, and NG-nitro-L-arginine methyl-ester (L NAME), a nitric oxide synthase inhibitor, on the morphine-induced sensitization and also on the expression of morphine ...
Hedayat Sahraei, Mohammad-Reza Zarrindast, Jamal Shams, Akram Eidi, Hassan Ghoshooni, Homeira Zardooz, Sara Sadeghi-Gharachehdaghi, Sara Bijani   +7 more
doaj   +2 more sources

The effect of cannabinoid type 2 receptor agonist on morphine tolerance

IBRO Neuroscience Reports
Pain highly impacts the quality of life of patients. Morphine is used for pain treatment; however, its side effects, especially morphine tolerance, limit its use in the clinic. The problem of morphine tolerance has plagued health workers and patients for
Di Cui, Yuanyuan Zhang, Mingyue Zhang
doaj   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Morphine Manifesto

Acta Médica Portuguesa, 2016
N ...
openaire   +4 more sources