Results 81 to 90 of about 339,726 (399)

Morphine Is Associated With a Delayed Activity of Oral Antiplatelet Agents in Patients With ST-Elevation Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

open access: yesCirculation. Cardiovascular Interventions, 2014
Background—Morphine is recommended in patients with ST-segment–elevation myocardial infarction, including those undergoing primary percutaneous coronary intervention.
G. Parodi   +10 more
semanticscholar   +1 more source

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin   +9 more
wiley   +1 more source

Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia.

open access: yesJournal of Clinical Investigation, 2014
The development of opioid-induced analgesic tolerance and hyperalgesia is a clinical challenge for managing chronic pain. Adaptive changes in protein translation in the nervous system are thought to promote opioid tolerance and hyperalgesia; however, how
Ji-Tian Xu   +12 more
semanticscholar   +1 more source

Comparison of morphine and morphine with ketamine for postoperative analgesia [PDF]

open access: yesCanadian Journal of Anaesthesia, 1996
The purpose of this study was to compare morphine with ketamine to morphine alone in a double-blind investigation of postsurgical pain control.Forty-two ASA 1 and 2 patients undergoing elective microdiscectomy were administered either 1 mg.ml-1 of morphine (n = 20) or 1 mg.ml-1 of both morphine and ketamine (n = 22) via iv patient controlled analgesia (
Keith B. Javery   +3 more
openaire   +3 more sources

Morphine stimulates cancer progression and mast cell activation and impairs survival in transgenic mice with breast cancer.

open access: yesBritish Journal of Anaesthesia, 2014
BACKGROUND Morphine stimulates angiogenesis and cancer progression in mice. We investigated whether morphine influences tumour onset, development, and animal model survival, and whether µ-opioid receptor (MOR), lymphangiogenesis, mast cell activation ...
J. Nguyen   +9 more
semanticscholar   +1 more source

Acute cardiovascular effects associated with the use of prescription medications: A Danish nationwide screening study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Saad Hanif Abbasi   +4 more
wiley   +1 more source

Management of patients with low back pain admitted to hospital: An observational study of usual care

open access: yesInternational Journal of Rheumatic Diseases, Volume 26, Issue 1, Page 60-68, January 2023., 2023
Abstract Background Knowledge gaps exist around diagnostic and treatment approaches for patients admitted to hospital with low back pain. Methods Medical record review of patients admitted to three Sydney teaching hospitals with a provisional emergency department diagnosis of non‐serious low back pain, from 2016 to 2020.
Alla Melman   +6 more
wiley   +1 more source

Influence of Nitric Oxide in the Central Amygdala on the Acquisition and Expression of Morphine-Induced Place Preference in Morphine Sensitized Rats

open access: yesBasic and Clinical Neuroscience, 2011
Effects of intra-central amygdala administration of L-arginine, a nitric oxide precursor, and NG-nitro-L-arginine methyl-ester (L NAME), a nitric oxide synthase inhibitor, on the morphine-induced sensitization and also on the expression of morphine ...
Hedayat Sahraei   +7 more
doaj   +2 more sources

Dopamine D4 receptor activation counteracts nigrostriatal pathway activation by morphine: relevance in drug addiction. [PDF]

open access: yes, 2013
Morphine induces dopamine release in the caudate putamen (CPu), which promotes stereotyped behavior and habit learning for drug-seeking and –taking. Nigrostriatal pathway stimulation by morphine is due to a removal of tonic inhibition arising from SNr ...
De-la-Calle-Martin, Adelaida   +7 more
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