Results 111 to 120 of about 10,950 (303)

Molecular Modeling Study on Morphine Derivatives Using Density Functional Methods and Molecular Descriptors [PDF]

, 2010
Dft 마약
openalex   +1 more source

Prevalence of Opioid Use and Associated Healthcare Outcomes in Rome IV Irritable Bowel Syndrome in the United Kingdom

Alimentary Pharmacology &Therapeutics, EarlyView.
One in five people with Rome IV irritable bowel syndrome use opioids on a regular basis. Compared with non‐users, opioid users had worse quality of life, greater psychological impairment, and higher direct healthcare costs. ABSTRACT Background The United Kingdom (UK) has one of the highest worldwide opioid prescription rates per capita.
Mohsin F. Butt, Vivek C. Goodoory, Cho Ee Ng, Christopher J. Black, Alexander C. Ford, Maura Corsetti, Peter Paine   +6 more
wiley   +1 more source

Sugar Derivatives of Morphine: A New Window for the Development of Potent Anesthetic Drugs [PDF]

, 2015
Shyamal K. Jash, Dilip Gorai
openalex   +1 more source

2,6-diazaspiro[3.4]octan-7-one derivatives as potent sigma-1 receptor antagonists that enhanced the antinociceptive effect of morphine and rescued morphine tolerance

, 2023
Kequan Fu, Wen Xu, Ruicong Yang, Huimin Zhao, Huanyu Xu, Yaqin Wei, Hongli Liu, Yinli Qiu, Danqi Chen, Dong Guo, Bing Xiong   +10 more
openalex   +1 more source

Birth Outcomes After Sexual Violence and the Role of Disclosure to the Maternity Care Provider

Birth, EarlyView.
ABSTRACT Background Sexual violence (SV) history is associated with various birth outcomes. Yet, the underlying mechanisms of these associations have not been sufficiently explained. Disclosure of SV history to a maternity care provider may play an important role in maternity care providers' choice for birth interventions and in women's birth ...
Hannah de Klerk, Janneke Gitsels, Ank de Jonge, Elsa Montgomery, Janneke van't Hooft, Marit van der Pijl, Martine Hollander, Corine Verhoeven   +7 more
wiley   +1 more source

Studies on Morphine Derivatives. II. The Stereochemistry of the By-products in the Synthesis of 3-Methoxy-N-methylmorphinan

, 1969
Kazuhiko Kawasaki, Hiromu Matsumura
openalex   +2 more sources

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Stabilized dynorphin derivatives for modulating antinociceptive activity in morphine tolerant rats: Effect of different routes of administration

, 2004
Boglarka Brugos, Vikram Arya, Günther Hochhaus   +2 more
openalex   +1 more source

The Enzymatic Deacetylation of Heroin and Related Morphine Derivatives by Blood Serum [PDF]

, 1941

openalex   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source