Results 111 to 120 of about 23,608 (143)

Synthesis of Morphine Alkaloids and Derivatives

2011
This review summarizes recent developments in the total synthesis of morphine alkaloids and some of the semisynthetic derivatives. The literature is covered for the period of 5 years after the publication of the last review in 2005. The syntheses that appeared in this period are covered in detail and are placed in the context of all syntheses of opiate
Uwe Rinner, Tomas Hudlicky
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Color Reactions of Morphine Derivatives.

Journal of Chemical & Engineering Data, 1966
T o CHECK the specificity of various tests for heroin, several esters of morphine and dihydromorphine were synthesized. These esters were treated with color-producing reagents and the results noted in Table I. Crystalline solids were obtained in other tests and the results are listed in Table 11.
Robert G. Splies, James M. Shellow
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14‐Alkyl‐substituierte Morphin‐Derivate

Chemische Berichte, 1979
AbstractDurch Claisen‐Eschenmoser‐Umlagerung von 1 erhält man 2b, das mit LiAlH4 in das 14‐[2‐(Dimethylamino)ethyl]codeinon‐acetal 2d übergeführt werden kann. Daraus entsteht mit CH3I das 14,17‐Ethanonorcodeinon‐acetal‐methoiodid 4a, das durch Reduktion mit LiBEt3H in sehr guter Ausbeute das 14‐Ethylcodeinon‐acetal 2g liefert, von dem eine Anzahl von ...
Wilhelm Fleischhacker, Bernd Richter
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Glucosides of morphine derivatives: synthesis and characterization

Monatshefte für Chemie - Chemical Monthly, 2012
Six 3-O- and 6-O-glucosides of morphine and codeine derivatives were synthesized by means of glucosylation with acetobromo-α-d-glucose. O-Glucosylation at C6 was carried out by the Koenigs-Knorr method, whereas the 3-O-glycoside of morphine was synthesized directly upon stirring morphine with acetobromo-α-d-glucose and aqueous sodium hydroxide in ...
Váradi, András, Lévai Dóra,, Tóth, Gergő, Horváth, Péter, Noszál, Béla, Hosztafi, Sándor   +5 more
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An antioxidant mechanism of morphine and related derivatives

Medicinal Chemistry Research, 2016
A structural and computational study of the morphine mechanism as an antioxidant or oxidant compound is performed by density functional theory (DFT) calculations. The geometry was obtained using the B3LYP/6-31G(d,p) method. The antioxidant property of morphine is related to the highest occupied molecular orbital (HOMO) energy, ionization potential (IP),
Rosivaldo S. Borges, Andrex A. S. Veiga, Glaécia A. N. Pereira, Joyce K. L. Vale, João Batista Júnior, Alberico Borges Ferreira da Silva   +5 more
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Biosynthesis of unnatural morphine derivatives in Papaver somniferum

Journal of the Chemical Society, Perkin Transactions 1, 1972
Demethylation of various codeine derivatives to give the corresponding, unnatural derivatives of morphine has been studied in Papaver somniferum. The efficiencies of the unnatural processes have been compared with that of the natural, codeine into morphine, conversion by feeding mixtures of [2-3H]-labelled codeine derivatives with [N-methyl-14C]codeine.
P. Steinreich, S. R. Massey, G. W. Kirby
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Über 14‐(Oxyalkyl)morphin‐Derivate

Chemische Berichte, 1979
Abstract14β‐(Dimethylcarbamoylmethyl)codeinon‐dimethylacetal (1a) sowie dessen Reduktionsprodukt 14β‐(2‐Hydroxyethyl)codeinon‐dimethylacetal (9) erleiden bei der sauren Acetalhydrolyse unerwartete Umlagerungen zu den Lactonen 5 und 6 bzw. den cyclischen Ethern 12 und 13a. Durch Isolierung der Zwischenprodukte 1b, 3, 5 bzw.
Bernd Richter, Wilhelm Fleischhacker
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ChemInform Abstract: 14‐(OXYALKYL)MORPHINE DERIVATIVES

Chemischer Informationsdienst, 1979
AbstractDas Dimethylcarbamoylmethyl‐codeindimethylacetal (I) und sein Reduktionsprodukt das 2‐Hydroxyethyl‐Derivat (V) erleiden bei der sauren Acetalhydrolyse unerwartete Umlagerungen zu dem Lacton (II) bzw. dem cyclischen Ether (VI) (optimale Ausb. 67 bzw. 91% in 2n HCl bei 100°C).
B. Richter, W. Fleischhacker
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ChemInform Abstract: Preparation of Benzoate Esters of Morphine and Its Derivatives

ChemInform, 2012
Abstract21 ...
Béni, Szabolcs, Tóth, Gergő, Noszál, Béla, Hosztafi, Sándor   +3 more
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Poisoning due to Opiates and Morphine Derivatives

1981
The deliberate self-administration of an opiate drug is a relatively common cause of poisoning in Great Britain, the USA and Europe. The group of opiate drugs is large and includes apomorphine, buprenor-phine, codeine and dihydrocodeine (DF 118), dextro-moramide, dextropropoxyphene (propoxyphene), diamorphine (diacetylmorphine, heroin), dipipanone ...
J. A. Vale, T. J. Meredith
openaire   +2 more sources