Results 141 to 150 of about 51,793 (252)

The Clinical Relevance of the Rectosigmoid Brake in Surgical Disorders and Therapies: A Systematic Review of Colonic Manometry Studies

Neurogastroenterology &Motility, Volume 38, Issue 3, March 2026.
Colonic motility mapping reveals a meal‐induced rectosigmoid brake in healthy individuals that is disrupted, disorganized, or exaggerated following surgery and in motility disorders. These alterations underlie conditions such as ileus, pseudo‐obstruction, and fecal incontinence, and may be modulated by sacral neuromodulation.
James A. Penfold, Cameron I. Wells, Ian P. Bissett, Gregory O'Grady   +3 more
wiley   +1 more source

Evaluation of the Enhanced Recovery After Surgery (ERAS) Guidance for Patients With Spinal Metastasis

Orthopaedic Surgery, Volume 18, Issue 3, Page 385-401, March 2026.
The flow diagram of study. ABSTRACT Surgery continues to remain the most effective treatment for spinal metastasis (SM). As the number of surgeries continues to grow, the need for consensus guidelines for optimal perioperative care is imperative. Enhanced recovery after surgery (ERAS) protocols were created for this purpose. The objective of this study
Fanjie Li, Wenlong Yu, Changchang Shen, Jinxin Luo, Zhibin Li, Qiang Gao, Chengchun Jin, Tao Li, Quan Huang, Shuqiang Wang, Peilin Chu, Mengchen Yin   +11 more
wiley   +1 more source

The YTHDF1-TRAF6 pathway regulates the neuroinflammatory response and contributes to morphine tolerance and hyperalgesia in the periaqueductal gray. [PDF]

J Neuroinflammation, 2022
Ouyang H, Zhang J, Chi D, Zhang K, Huang Y, Huang J, Huang W, Bai X.   +7 more
europepmc   +1 more source

Co-Administration of nalbuphine to improve morphine tolerance in mice with bone cancer pain. [PDF]

Mol Pain, 2023
Ren B, Zhang J, Yang X, Sun D, Sheng D, Fang Q, Ji Z.   +6 more
europepmc   +1 more source

Molecular identification of bulbospinal ON neurons by GPER, which drives pain and morphine tolerance. [PDF]

J Clin Invest, 2023
Jiao Y, Gao P, Dong L, Ding X, Meng Y, Qian J, Gao T, Wang R, Jiang T, Zhang Y, Kong D, Wu Y, Chen S, Xu S, Tang D, Luo P, Wu M, Meng L, Wen D, Wu C, Zhang G, Shi X, Yu W, Rong W.   +23 more
europepmc   +1 more source

The role of nucleus accumbens dopamine signaling in the development of morphine tolerance in neuropathic pain. [PDF]

Korean J Pain
Cui S, Kim WM, Jang EA, Lee YJ, Kang DH, Lee HG, Choi JI.   +6 more
europepmc   +1 more source

The therapeutic potential of phytochemicals in morphine tolerance: targeting microglia-mediated neuroinflammation. [PDF]

Front Pharmacol
Shi R, Jin T, Xu W, Liang Y.
europepmc   +1 more source

Teneligliptin Co-Infusion Alleviates Morphine Tolerance by Inhibition of Spinal Microglial Cell Activation in Streptozotocin-Induced Diabetic Rats. [PDF]

Antioxidants (Basel), 2023
Kuthati Y, Rao VN, Huang WH, Busa P, Wong CS.   +4 more
europepmc   +1 more source

Erianin ameliorates morphine tolerance and glioma progression through the JAK2-STAT3 pathway. [PDF]

Transl Oncol
Gu Y, Xu J, Ding X, Wan S, Cai F, Qin H.
europepmc   +1 more source

Early-life adversity increases morphine tolerance and persistent inflammatory hypersensitivity through upregulation of δ opioid receptors in mice. [PDF]

Pain, 2023
Singleton S, Sneddon C, Bakina A, Lambert JJ, Hales TG.   +4 more
europepmc   +1 more source