Results 181 to 190 of about 51,793 (252)

Blocking Palmitoylation of Apelin Receptor Alleviates Morphine Tolerance in Neuropathic Cancer Pain. [PDF]

Int J Biol Sci
Fan X, Gong M, Zhang S, Niu W, Sun S, Yu H, Chen X, Fang Z.   +7 more
europepmc   +1 more source

Ferroptosis inhibitor ferrostatin-1 attenuates morphine tolerance development in male rats by inhibiting dorsal root ganglion neuronal ferroptosis. [PDF]

Korean J Pain
Dirik H, Taşkıran AŞ, Joha Z.
europepmc   +1 more source

Biasing G<i>βγ</i> Downstream Signaling with Gallein Inhibits Development of Morphine Tolerance and Potentiates Morphine-Induced Nociception in a Tolerant State. [PDF]

Mol Pharmacol
Sanchez GA, Smrcka AV, Jutkiewicz EM.
europepmc   +1 more source

Genetically supported causality between gut microbiota, immune cells and morphine tolerance: a two-sample Mendelian randomization study. [PDF]

Front Microbiol
Han S, Gao J, Wang Z, Xiao Y, Ge Y, Liang Y, Gao J.   +6 more
europepmc   +1 more source

Cannabinoid CB₂ receptors in primary sensory neurons are implicated in CB₂ agonist-mediated suppression of paclitaxel-induced neuropathic nociception and sexually-dimorphic sparing of morphine tolerance. [PDF]

Biomed Pharmacother
Guenther KG, Lin X, Xu Z, Makriyannis A, Romero J, Hillard CJ, Mackie K, Hohmann AG.   +7 more
europepmc   +1 more source

Molecular basis of morphine tolerance

Japanese Journal of Pharmacology, 2000
openaire   +1 more source

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Morphine-Induced Attenuation of Morphine Tolerance

Science, 1981
Rats experienced both morphine and an environmental cue, but the cue always signaled a drug-free period. They were subsequently administered morphine in the presence of the cue, and the development of analgesic tolerance was assessed. The prior experience retarded such tolerance.
S, Siegel, R E, Hinson, M D, Krank
openaire   +2 more sources

Morphine: Single-Dose Tolerance

Science, 1968
Rats show a significant degree of tolerance to a second dose of morphine, with the degree of tolerance increasing the longer the delay between the two doses of morphine. To measure the morphine effect a foot-shock attenuation procedure that allowed the animal to adjust the shock intensity was used in studying delays of up to 180 days.
C, Kornetsky, G, Bain
openaire   +2 more sources

Morphine Metabolism and Morphine Tolerance in Goldfish

Anesthesiology, 1970
Tolerance to morphine was induced in goldfish shown to be unable to metabolize morphine. Ability to metabolize is, therefore not a prercquisite to development of tolerance.
G A, Jansen, N M, Greene
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Morphine tolerance in hepatic cirrhosis

Gastroenterology, 1961
Summary Electroencephalogram (EEG) recordings were made in 32 subjects on 36 occasions before administration of 8 mg. or 16 mg. of morphine subcutaneously, and 3 hours thereafter. The method of measuring and grading the EEG response is described. Eight mg.
J, LAIDLAW, A E, READ, S, SHERLOCK
openaire   +2 more sources