Results 11 to 20 of about 673,537 (375)

The mechanics of plant morphogenesis

open access: yesScience, 2023
Understanding the mechanism by which patterned gene activity leads to mechanical deformation of cells and tissues to create complex forms is a major challenge for developmental biology.
E. Coen, D. Cosgrove
semanticscholar   +1 more source

3D in vitro morphogenesis of human intestinal epithelium in a gut-on-a-chip or a hybrid chip with a cell culture insert

open access: yesNature Protocols, 2022
Human intestinal morphogenesis establishes 3D epithelial microarchitecture and spatially organized crypt–villus characteristics. This unique structure is necessary to maintain intestinal homeostasis by protecting the stem cell niche in the basal crypt ...
Woojung Shin, Hyun Jung Kim
semanticscholar   +1 more source

Competitive PCR with dual fluorescent primers enhances the specificity and reproducibility of genotyping animals generated from genome editing

open access: yesCell & Bioscience, 2023
Targeted genome editing is a powerful tool for studying gene function in almost every aspect of biological and pathological processes. The most widely used genome editing approach is to introduce engineered endonucleases or CRISPR/Cas system into cells ...
Liezhen Fu   +4 more
doaj   +1 more source

Synthetic Morphogenesis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2016
Throughout biology, function is intimately linked with form. Across scales ranging from subcellular to multiorganismal, the identity and organization of a biological structure's subunits dictate its properties. The field of molecular morphogenesis has traditionally been concerned with describing these links, decoding the molecular mechanisms that give ...
Brian P, Teague   +2 more
openaire   +2 more sources

Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

open access: yesNature Communications, 2020
SARS-CoV-2, a β-coronavirus, has rapidly spread across the world, highlighting its high transmissibility, but the underlying morphogenesis and pathogenesis remain poorly understood.
N. Zhu   +18 more
semanticscholar   +1 more source

The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli

open access: yeseLife, 2020
Bacterial shape is physically determined by the peptidoglycan cell wall. The cell-wall-synthesis machinery responsible for rod shape in Escherichia coli is the processive 'Rod complex'.
Gizem Özbaykal   +8 more
doaj   +1 more source

Immunocompetent Mice Infected by Two Lineages of Dengue Virus Type 2: Observations on the Pathology of the Lung, Heart and Skeletal Muscle

open access: yesMicroorganisms, 2021
Dengue virus (DENV) infection by one of the four serotypes (DENV-1 to 4) may result in a wide spectrum of clinical manifestations, with unpredictable evolution and organ involvement.
Fernanda Cunha Jácome   +10 more
doaj   +1 more source

Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis [PDF]

open access: yes, 1997
The characteristic shapes and positions of each individual body muscle are established during the process of muscle morphogenesis in response to patterning information from the surrounding mesenchyme. Throughout muscle morphogenesis, primary myotubes are
Adams   +37 more
core   +3 more sources

Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome

open access: yesNature Communications, 2021
Leigh syndrome (LS) is a severe manifestation of mitochondrial disease in children and is currently incurable. The lack of effective models hampers our understanding of the mechanisms underlying the neuronal pathology of LS. Using patient-derived induced
Gizem Inak   +32 more
semanticscholar   +1 more source

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