Results 21 to 30 of about 673,537 (375)

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]

open access: yes, 2012
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna   +3 more
core   +2 more sources

Toward high-content/high-throughput imaging and analysis of embryonic morphogenesis [PDF]

open access: yes, 2011
In vivo study of embryonic morphogenesis tremendously benefits from recent advances in live microscopy and computational analyses. Quantitative and automated investigation of morphogenetic processes opens the field to high-content and high-throughput ...
Supatto, Willy, Truong, Thai V.
core   +4 more sources

Morphological Aspects and Viremia Analysis of BALB/c Murine Model Experimentally Infected with Dengue Virus Serotype 4

open access: yesViruses, 2021
Ever since its brief introduction in the Brazilian territory in 1981, dengue virus serotype 4 (DENV-4) remained absent from the national epidemiological scenario for almost 25 years. The emergence of DENV-4 in 2010 resulted in epidemics in most Brazilian
Arthur da Costa Rasinhas   +13 more
doaj   +1 more source

Neuroepithelial organoid patterning is mediated by a neighborhood watch mechanism

open access: yesCell Reports, 2023
Summary: During epithelial tissue patterning, morphogens operate across multiple length scales to instruct cell identities. However, how cell fate changes are coordinated over these scales to establish spatial organization remains poorly understood. Here,
Abdel Rahman Abdel Fattah   +4 more
doaj   +1 more source

Branching Morphogenesis [PDF]

open access: yesCirculation Research, 2008
Tubular structures are a fundamental anatomic theme recurring in a wide range of animal species. In mammals, tubulogenesis underscores the development of several systems and organs, including the vascular system, the lungs, and the kidneys.
Arie, Horowitz, Michael, Simons
openaire   +3 more sources

Integer topological defects organize stresses driving tissue morphogenesis

open access: yesbioRxiv, 2020
Tissues acquire their function and shape via differentiation and morphogenesis. Both processes are driven by coordinating cellular forces and shapes at the tissue scale, but general principles governing this interplay remain to be discovered.
Pau Guillamat   +3 more
semanticscholar   +1 more source

Distinct molecular cues ensure a robust microtubule-dependent nuclear positioning in the Drosophila oocyte

open access: yesNature Communications, 2017
Asymmetric nuclear positioning in the fruit fly oocyte is essential for the correct localization of axis determinants. Here, the authors show that different microtubule-dependent mechanisms contribute to nuclear transport and ensure the robustness of ...
Nicolas Tissot   +9 more
doaj   +1 more source

A method to generate the surface cell layer of the 3D virtual shoot apex from apical initials

open access: yesPlant Methods, 2017
Background The development of cell pattern in the surface cell layer of the shoot apex can be investigated in vivo by use of a time-lapse confocal images, showing naked meristem in 3D in successive times. However, how this layer is originated from apical
Krzysztof Kucypera   +3 more
doaj   +1 more source

Neurotrophin signaling is a central mechanism of salivary dysfunction after irradiation that disrupts myoepithelial cells

open access: yesnpj Regenerative Medicine, 2023
The mechanisms that prevent regeneration of irradiated (IR) salivary glands remain elusive. Bulk RNAseq of IR versus non-IR human salivary glands showed that neurotrophin signaling is highly disrupted post-radiation.
Alejandro M. Chibly   +13 more
doaj   +1 more source

Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface. [PDF]

open access: yes, 2018
Orofacial clefting represents the most common craniofacial birth defect. Cleft lip with or without cleft palate (CL/P) is genetically distinct from cleft palate only (CPO).
Berkes   +78 more
core   +1 more source

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