Results 71 to 80 of about 673,537 (375)

Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during Xenopus tropicalis metamorphosis

open access: yesCell & Bioscience, 2020
Background Thyroid hormone (T3) plays an important role in vertebrate development. Compared to the postembryonic development of uterus-enclosed mammalian embryos, T3-dependent amphibian metamorphosis is advantageous for studying the function of T3 and T3
Wonho Na   +3 more
doaj   +1 more source

Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses

open access: yesBMC Oral Health, 2023
Background Ameloblastic carcinoma and metastasising ameloblastoma are rare epithelial odontogenic tumours with aggressive features. Distinguishing between these two lesions is often clinically difficult but necessary to predict tumour behaviour or to ...
Pavel Hurník   +10 more
doaj   +1 more source

Integrins and morphogenesis

open access: yesDevelopment, 1993
ABSTRACT The Drosophila position specific (PS) integrins consist of two cell surface heterodimers, PS1 (αPS1βPS) and PS2 (αPS2βPS), which are expressed on complementary sides of attachments between cell layers and are essential for these attachments.
Brown, Nicholas H.   +3 more
openaire   +3 more sources

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

ELMO2 is an essential regulator of carotid artery development

open access: yesNature Communications
Engulfment and cell motility 2 (ELMO2) is a cytoskeletal adaptor protein necessary for cell migration and apoptotic cell removal. Loss-of-function mutations in ELMO2 cause intraosseous vascular malformation (VMOS), a human disease involving progressive ...
Athira Suresh   +4 more
doaj   +1 more source

The Morphogenesis Of Evolutionary Developmental Biology [PDF]

open access: yes, 2003
The early studies of evolutionary developmental biology (Evo-Devo) come from several sources. Tributaries flowing into Evo-Devo came from such disciplines as embryology, developmental genetics, evolutionary biology, ecology, paleontology, systematics ...
Gilbert, Scott F.
core   +2 more sources

Exploiting Two‐Photon Lithography, Deposition, and Processing to Realize Complex 3D Magnetic Nanostructures

open access: yesAdvanced Functional Materials, EarlyView.
Two‐photon lithography (TPL) enables 3D magnetic nanostructures with unmatched freedom in geometry and material choice. Advances in voxel control, deposition, and functionalization open pathways to artificial spin ices, racetracks, microrobots, and a number of additional technological applications.
Joseph Askey   +5 more
wiley   +1 more source

An updated classification of hair follicle morphogenesis

open access: yesExperimental Dermatology, 2019
Hair follicle (HF) formation in developing embryonic skin requires stepwise signalling between the epithelial epidermis and mesenchymal dermis, and their specialized derivatives, the placode/germ/peg and dermal condensate/papilla, respectively ...
Nivedita Saxena   +2 more
semanticscholar   +1 more source

Multiple Twinning in Nacre and Aragonite

open access: yesAdvanced Functional Materials, EarlyView.
Electron backscatter diffraction map of a cluster of geologic aragonite, exhibiting single, double, and triple twins. The whole cluster is approximately 2 cm wide. Colors indicate crystal orientations, so that pixels where the a‐, b‐, and c‐axis is perpendicular to the image plane are green, red, and blue, respectively.
Connor A. Schmidt   +7 more
wiley   +1 more source

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