Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Bone Morphogenetic Protein (BMP) 9 Outperforms BMP2 in Osteogenesis and Osseointegration: In Vitro and In Vivo. [PDF]
Han HS +9 more
europepmc +1 more source
ABSTRACT Background Immunotherapy response rates in head and neck squamous cell carcinoma (HNSCC) are limited by multiple factors. Tumor cell‐derived follistatin (FST) has been linked to immunotherapy resistance, but the underlying mechanisms remain poorly understood. This study aimed to investigate the prognostic value of FST and its associations with
Pan Song +6 more
wiley +1 more source
Spatial Gene Expression in Fungi: mRNA Localization, Condensates, and Beyond
ABSTRACT Polarized growth and cellular asymmetry are broadly conserved properties of fungal life, from transient bud‐site selection in unicellular yeasts to sustained hyphal extension in filamentous and coenocytic species. While vesicle trafficking, cytoskeletal organization, and cell‐wall remodeling are well‐established contributors to these processes,
Sander van Otterdijk +3 more
wiley +1 more source
The effectiveness of using recombinant human bone morphogenetic protein-2 in the reconstruction of alveolar clefts: a meta-analysis. [PDF]
Xu H, Liu Z.
europepmc +1 more source
Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika +6 more
wiley +1 more source
Alveolar Ridge Preservation Using Low Dosage Bone Morphogenetic Protein 2 Incorporated Biomimetic Calcium Phosphate. [PDF]
Zhang W +5 more
europepmc +1 more source
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider +48 more
wiley +1 more source
Bone morphogenetic protein 4 meets artificial intelligence: a comprehensive review of AI-driven advances in drug discovery, structural modeling, and clinical translation. [PDF]
Sun W, Huo T, Ye Z, Wei W, Sun Y, Cai H.
europepmc +1 more source
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong +14 more
wiley +1 more source

