Results 181 to 190 of about 4,458,570 (286)

The fight of innate immunity and abnormal cannabinoids against Candida infection

British Journal of Pharmacology, EarlyView.
Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori, Ilan Zaffran, Francesca Levi Schaffer   +2 more
wiley   +1 more source

Bone Morphogenetic Protein [PDF]

, 2020
openaire   +2 more sources

Regional diversity of cranial skeletal stem cells governs bone morphogenetic protein-2 mediated bone regeneration. [PDF]

Nat Commun
Takematsu E, Lachmansingh RN, Johnston K, Hou S, Bailey E, Wang Y, Zhao L, Hoover M, Nguyen HTM, Parmar KM, Talbott H, Longaker MT, Chan CKF.   +12 more
europepmc   +1 more source

Novel PAX9 Stop Mutation Associated With Selective Tooth Agenesis and Variable Expressivity in an Austrian‐Hungarian Family

Clinical Genetics, EarlyView.
Here, we describe a novel heterozygous PAX9 stop mutation (c.576G>A; p.Trp192*) causing selective tooth agenesis in a family with three affected members across two generations. Phenotypes show marked intrafamilial variability, including oligodontia with anterior tooth involvement, shape abnormalities, and deciduous dentition disruption.
Katharina Sillaber, Ines Kapferer‐Seebacher, Katharina Herzog, Balázs J. Dénes, Johannes Zschocke   +4 more
wiley   +1 more source

Bone morphogenetic protein signaling drives rete ridge morphogenesis: a distinct epidermal appendage program. [PDF]

Signal Transduct Target Ther
Lee DG, Kim SU, Park YH.
europepmc   +1 more source

Cell‐Migration Visualization: Task Taxonomy, Systematic Review and Research Agenda

Computer Graphics Forum, EarlyView.
We present an expert‐validated task taxonomy for cell migration analysis and a PRISMA‐based systematic review that maps visualization tools to the tasks they support and the techniques they employ. This synthesis identifies current gaps and outlines opportunities for future research in cell migration visualization.
Ana Carla Correia, Thifany Souza, Ana Carolina Correia, Nivan Ferreira   +3 more
wiley   +1 more source

Xylt2 Knockout Eliminates O-Xylosylation and Enhances Bone Morphogenetic Protein 2 Production in Chinese Hamster Ovary Cells. [PDF]

Biotechnol J
Han L, Wu N, Li Q, Li Y, Zhang Y, Chen X, Zhou H, Chen F, Sun T.   +8 more
europepmc   +1 more source

Tetrahedral Framework Nucleic Acid Delivery of miR‐210‐3p Promotes Femoral Bone Regeneration Through EFNA3/AKT/STAT3‐Mediated Immunomodulation

Cell Proliferation, EarlyView.
Schematic of tFNA‐miR‐210‐3p fabrication, macrophage regulation and femoral defect therapy: it enters macrophages, inhibits EFNA3 to induce M2 polarisation and boosts rat bone repair in vivo. ABSTRACT Persistent inflammation, insufficient vascularization and impaired osteogenesis limit the repair of critical‐sized femoral defects. Although microRNA‐210‐
Lei Hu, Kaixiao Xue, Jiahu Fang, Weitong Cui   +3 more
wiley   +1 more source

Pulmonary Hypertension in a 19-Year-Old Patient Due to a Mutation in the Bone Morphogenetic Protein Receptor Gene: A Case Report. [PDF]

Cureus
Pelloni F, De Perna ML, Moschovitis G.
europepmc   +1 more source

Cellular Proliferation and Reprogramming in Pre‐Metastatic Niches: Mechanisms and Therapeutic Vulnerabilities

Cell Proliferation, EarlyView.
This review systematically elucidates how primary tumours remotely drive multicellular reprogramming to construct the pre‐metastatic niche and dictate disseminated tumour cell fate. By mapping this dynamic ecosystem, we identify actionable therapeutic vulnerabilities, advocating a paradigm shift from traditional cytotoxicity toward microenvironment ...
Shengqian Wang, Chenghu Song, Pengfei Li, Junjie Feng, Xiaoxuan Shi, Qiwen Lu, Bohan Duan, Xinyan Zhang, Siqi Li, Yang Luo, Xiaohui Fan, Ziyun Li, Yang Zhang, Renjun Gu, Wenjun Mao   +14 more
wiley   +1 more source