Results 201 to 210 of about 4,458,570 (286)

SHIP1 regulates TREM2 signalling and macrophage functions in a hiPSC‐derived model

open access: yesThe FEBS Journal, EarlyView.
In this study, we characterised the role of SHIP1 in regulating TREM2 signalling and global microglial myeloid functions using human‐induced pluripotent stem cell (hiPSC)‐derived macrophages. Knockout of SHIP1 (SHIP1 KO) in macrophages decreased inflammatory activation and levels of scavenger receptors. SHIP1 KO macrophages also exhibited reduced TREM2
Kim S. Martin   +5 more
wiley   +1 more source

Treatment of femoral defects in rats with collagen and elastin polymers combined with hydroxyapatite and bone morphogenetic protein. [PDF]

open access: yesFront Bioeng Biotechnol
Machado EG   +13 more
europepmc   +1 more source

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

open access: yesThe FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon   +4 more
wiley   +1 more source

The Use of Recombinant Bone Morphogenetic Protein-2 in the Treatment of Spondylodiscitis. [PDF]

open access: yesGlobal Spine J
Nishizawa M   +6 more
europepmc   +1 more source

Ethylenediaminetetraacetic Acid and Other Dentine Bioactive Molecule‐Releasing Agents for Regenerative Endodontic Procedures: A Systematic Review

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background The bioactive molecules released from dentine are key to stem‐cell recruitment, proliferation and differentiation in regenerative endodontics. However, there is limited and conflicting information regarding current and potential agents for releasing dentine bioactive molecules for regenerative endodontic procedures.
Arwa Al‐Maswary   +4 more
wiley   +1 more source

Tacit Publication Norms and the Staging of Epistemic Commitment: A Corpus Study of Life‐Science Journal Tiers

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This study examines how epistemic commitment is temporally and syntactically staged across journal tiers in life‐science research writing. Drawing on a 2.3‐million‐word corpus of 320 publications in biochemistry, genetics, and molecular biology, it compares higher‐tier journals with a SCImago Journal Rank (SJR) value of 2.000 or above ...
Ezra Alexander
wiley   +1 more source

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