Results 21 to 30 of about 4,458,570 (286)

An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension

Nature Communications, 2021
Pulmonary arterial hypertension is a progressive fatal disease characterized by pathological pulmonary artery remodeling. Here the authors show that the dysregulation of the activin A-bone morphogenetic protein receptor type 2 link in the endothelium is ...
Gusty R. T. Ryanto, Koji Ikeda, Kazuya Miyagawa, Ly Tu, Christophe Guignabert, Marc Humbert, Tomoyuki Fujiyama, Masashi Yanagisawa, Ken-ichi Hirata, Noriaki Emoto   +9 more
doaj   +1 more source

Association of Bone Morphogenetic Proteins With Otosclerosis [PDF]

Journal of Bone and Mineral Research, 2008
Abstract We studied the role of polymorphisms in 13 candidate genes on the risk of otosclerosis in two large independent case-control sets. We found significant association in both populations with BMP2 and BMP4, implicating these two genes in the pathogenesis of this disease.
Schrauwen, Isabelle, Thys, Melissa, Vanderstraeten, Kathleen, Fransen, Erik, Dieltjens, Nele, Huyghe, Jeroen R., Ealy, Megan, Claustres, Mireille, Cremers, Cor R.W.J., Dhooge, Ingeborg, Declau, Frank, Van de Heyning, Paul, Vincent, Robert, Somers, Thoams, Offeciers, Erwin, Smith, Richard J.H., Van Camp, Guy   +16 more
openaire   +3 more sources

Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]

, 2005
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
core   +1 more source

INVESTIGATION THE POLYMORPHISM OF BONE MORPHOGENETIC PROTEIN 15 (BMP-15) GENE IN IRAQ COW [PDF]

Basrah Journal of Veterinary Research, 2016
Bone Morphogenetic Protein 15 (BMP-15) was known to regulate functions of ovaryin mammals. The aim of this research was tocompare the BMP15 expression ofovaries incow and calf todetermine a relationship between the level of BMP15 genesand the ...
Hayder AL-Mutar
doaj   +1 more source

Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development [PDF]

, 2008
Background: Adrenal chromaffin cells and sympathetic neurons both originate from the neural crest, yet signals that trigger chromaffin development remain elusive.
Huber, Katrin, Halbach Oliver, Kalcheim Chaya, Krispin, S., Krispin Shlomi, Huber, K., Oliver von Bohlen und Halbach, Hermann Rohrer, Unsicker, K., Rohrer, H., Aylin Franke, Shlomi Krispin, Franke Aylin, Ernsberger, U., Unsicker, Klaus, Brühl, Barbara, Huber Katrin, Schober Andreas, Ernsberger Uwe, Chaya Kalcheim, Barbara Brühl, Klaus Unsicker, von Bohlen und Halbach, O., Franke, Aylin, Brühl Barbara, Bohlen und Halbach, Oliver von, Schober, A., Ernsberger, Uwe, Kalcheim, Chaya, Rohrer, Hermann, Rohrer Hermann, Andreas Schober, Schober, Andreas, Krispin, Shlomi, Unsicker Klaus, Brühl, B., Kalcheim, C., Franke, A., Katrin Huber, Uwe Ernsberger   +39 more
core   +1 more source

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Expression of human bone morphogenetic protein (BMP-2 and BMP-4) genes in transgenic bovine fibroblasts Expressão dos genes bone morphogenetic protein (BMP-2 e BMP-4) em fibroblastos bovinos transgênicos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
cDNAs dos genes bone morphogenetic protein-2 (BMP-2) e bone morphogenetic protein-4 (BMP-4) foram sintetizados a partir de RNA total extraído de tecidos ósseos de pacientes que apresentavam trauma facial (fraturas do maxilar entre o 7º e o 10º dia pós ...
C. Oleskovicz, S. Lisauskas, F.J.L. Aragão   +2 more
doaj   +1 more source

RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis [PDF]

, 2012
Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell differentiation and axon guidance.
Coutinho, L., Ahmed, Mohi, Jorge, Erika Cristina, Dietrich, Susanne, Bothe, I., Ahmed, Mohi U., Coutinho, Luiz Lehmman, Ahmed, M., Bothe, Ingo, Jorge, E.   +9 more
core   +1 more source

Identification of SpoVID as a putative new substrate of the sporulation-specific protease YabG in Bacillus subtilis

Frontiers in Microbiology
Bacillus subtilis YabG, a cysteine protease expressed in mother cells during sporulation, is involved in the processing of spore coat proteins. However, the full spectrum of YabG substrates and the physiological significance of its proteolytic activity ...
Ritsuko Kuwana, Yasuhiro Kasahara, Kiyoshi Ito, Hiromu Takamatsu   +3 more
doaj   +1 more source

Bone Morphogenetic Protein Coating on Titanium Implant Surface: a Systematic Review

eJournal of Oral Maxillofacial Research, 2017
Objectives: The purpose of the study is to systematically review the osseointegration process improvement by bone morphogenetic protein coating on titanium implant surface.
Haim Haimov, Natali Yosupov, Ginnady Pinchasov, Gintaras Juodzbalys   +3 more
doaj   +1 more source