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Design, synthesis, in silico studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine [PDF]

open access: yesFrontiers in Chemistry
IntroductionCancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. These cells can invade nearby tissues and organs, or they may metastasize to other parts of the body through the ...
Elaheh Ataollahi   +10 more
doaj   +2 more sources

(Morpholin-4-yl)[2-(morpholin-4-yl)-3,5-dinitrophenyl]methanone [PDF]

open access: yesActa Crystallographica Section E, 2012
In the title compound, C15H18N4O7, the morpholine rings adopt chair conformations. The benzene ring forms dihedral angles of 55.94 (7) and 63.19 (7)° with the planes through the C atoms of the two morpholine rings.
Chao Gao   +3 more
doaj   +3 more sources

Behavior of morpholine and its trimethylsilyl derivative in reactions with trimethylsilyl isocyanate

open access: yesТонкие химические технологии, 2022
Objectives. To study the patterns of behavior of morpholine and its trimethylsilyl derivative in reactions with trimethylsilyl isocyanate.Methods. The study employed infrared and nuclear magnetic resonance spectroscopy, as well as elemental analysis ...
L. O. Belova   +4 more
doaj   +1 more source

Overview of Piperidine and Morpholine Derivatives as Promising Sources of Biologically Active Compounds (Review)

open access: yesРазработка и регистрация лекарственных средств, 2023
Introduction. The search for new, effective and safe pharmacologically active substances remains an urgent task in the field of pharmacy. Many compounds of the piperidine and morpholine series are widely used in medical practice and belong to an ...
A. E. Khamitova, D. A. Berillo
doaj   +1 more source

Crystal structures of the isotypic complexes bis(morpholine)gold(I) chloride and bis(morpholine)gold(I) bromide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2023
The compounds bis(morpholine-κN)gold(I) chloride, [Au(C4H9NO)2]Cl, 1, and bis(morpholine-κN)gold(I) bromide, [Au(C4H9NO)2]Br, 2, crystallize isotypically in space group C2/c with Z = 4. The gold atoms, which are axially positioned at the morpholine rings,
Cindy Döring, Peter G. Jones
doaj   +1 more source

Morpholin-4-ium morpholine-4-carbodithioate [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2011
The title compound, C(4)H(10)NO(+)·C(5)H(8)NOS(2) (-), is built up of a morpholinium cation and a dithio-carbamate anion. In the crystal, two structurally independent formula units are linked via N-H⋯S hydrogen bonds, forming an inversion dimer, with graph-set motif R(4) (4)(12).
Ana C. Mafud   +2 more
openaire   +3 more sources

Glycine/Glycolic acid based copolymers [PDF]

open access: yes, 1994
Glycine/glycolic acid based biodegradable copolymers have been prepared by ring-opening homopolymerization of morpholine-2,5-dione, and ring-opening copolymerization of morpholine-2,5-dione and glycolide.
Dijkstra, Pieter J.   +4 more
core   +15 more sources

Highly efficient morpholine-based organocatalysts for the 1,4-addition reaction between aldehydes and nitroolefins: an unexploited class of catalysts

open access: yesFrontiers in Chemistry, 2023
Many studies have demonstrated how the pyrrolidine nucleus is more efficient than the corresponding piperidine or morpholine as organocatalysts in the condensation of aldehydes with electrophiles via enamine.
Francesco Vaghi   +6 more
doaj   +1 more source

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