Results 41 to 50 of about 24,393 (218)

A paracetamol–morpholine adduct

Acta Crystallographica Section E Structure Reports Online, 2002
Paracetamol [also known as acet­amino­phen or N-(4-hydroxy­phenyl)­acet­amide] is an important analgesic drug that has recently been cocrystallized with a series of cyclic N- and O-donor compounds. This paper describes the formation of a paracetamol adduct with morpholine, viz. paracetamol–morpholine (1/2.5), C8H9NO2·2.5C4H9NO.
Oswald, I D H, Motherwell, W D S, Parsons, S, Pulham, C R   +3 more
openaire   +3 more sources

Design, synthesis, in silico studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine

Frontiers in Chemistry
IntroductionCancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. These cells can invade nearby tissues and organs, or they may metastasize to other parts of the body through the ...
Elaheh Ataollahi, Leila Emami, Al-Anood Mohammad Al-Dies, Fateme Zare, Alireza Poustforoosh, Mina Emami, Fateme Saadat, Fateme Motamen, Zahra Rezaei, Soghra Khabnadideh, Soghra Khabnadideh   +10 more
doaj   +1 more source

Katalytischer Schwefelatomtransfer vermittelt durch einen Bis(disulfido)‐Titankomplex

Angewandte Chemie, EarlyView.
Mehrelektronentransformationen mit Titan sind aufgrund der limitierten Zugänglichkeit niedervalenter Vorstufen bislang nur unzureichend untersucht. Die Vier‐Elektronen‐Aktivierung von elementarem Schwefel durch einen Ti(IV)‐Komplex führt zu einem seltenen Bis(disulfido)‐Titankomplex, der die effiziente katalytische Synthese von Isothiocyanaten aus ...
Sebastian Samir Cremer, Peter Coburger, Corinna Czernetzki, Gabriele Hierlmeier   +3 more
wiley   +1 more source

Ammonium Salts of 5-(3-Chromenyl)-5H-chromeno[2,3-b]pyridines

Molbank, 2021
The ammonium salts of many drugs have significantly improved the solubility and, accordingly, the bioavailability of medicinal substances in the human body.
Yuliya E. Ryzhkova, Artem N. Fakhrutdinov, Michail N. Elinson   +2 more
doaj   +1 more source

(Morpholin-4-yl)[2-(morpholin-4-yl)-3,5-dinitrophenyl]methanone

Acta Crystallographica Section E, 2012
In the title compound, C15H18N4O7, the morpholine rings adopt chair conformations. The benzene ring forms dihedral angles of 55.94 (7) and 63.19 (7)° with the planes through the C atoms of the two morpholine rings.
Chao Gao, Ying Xiong, Yong Xia, Luo-Ting Yu   +3 more
doaj   +1 more source

Thiourea Derivative Metal Complexes: Spectroscopic, Anti-Microbial Evaluation, ADMET, Toxicity, and Molecular Docking Studies

Inorganics, 2023
The treatment of N-Phenylmorpholine-4-carbothioamide (HPMCT) with bivalent metal ions in a 2:1 mol ratio without a base present affords [MCl2(κ1S-HPMCT)2] {M = Cu(1), Pd(2), Pt(3), and Hg(4)} in a good yield.
Ahmed T. F. Al-Halbosy, Adnan A. Hamada, Ahmed S. Faihan, Abdulrahman M. Saleh, Tarek A. Yousef, Mortaga M. Abou-Krisha, Mona H. Alhalafi, Ahmed S. M. Al-Janabi   +7 more
doaj   +1 more source

Crystal structure and theoretical study of (2E)-1-[4-hydroxy-3-(morpholin-4-ylmethyl)phenyl]-3-(thiophen-2-yl)prop-2-en-1-one

Acta Crystallographica Section E: Crystallographic Communications, 2018
In the title compound, C18H19NO3S, the morpholine ring adopts a chair conformation. The thiophene ring forms dihedral angles of 26.04 (9) and 74.07 (10)° with the benzene ring and the mean plane of the morpholine ring, respectively.
Fatma Yesilyurt, Abdullah Aydin, Halise Inci Gul, Mehmet Akkurt, Nefise Dilek Ozcelik   +4 more
doaj   +1 more source

Chronic morpholine exposure of rats

Fundamental and Applied Toxicology, 1989
The chronic toxicity and carcinogenic potential of morpholine were evaluated in 60 Sprague-Dawley rats/sex/group receiving morpholine at mean inhalation exposure concentrations of 0, 10, 50 and 150 ppm for 6 hr/day, 5 days/week, for 104 weeks. Survival, body weight gains, organ weights, hematology, and clinical chemistries were normal in exposed groups
Center for Environmental Toxicology, University of Florida, Alachua, Florida 32615 USA ( host institution ), Harbison, Raymond D., Marino, Dale J., Conaway, C.Clifford, Rubin, Lionel F., Gandy, Jay   +5 more
openaire   +3 more sources

Synthesis of Novel N-Methylmorpholine-Substituted Benzimidazolium Salts as Potential α-Glucosidase Inhibitors

Molecules, 2022
The α-glucosidase enzyme, located in the brush border of the small intestine, is responsible for overall glycemic control in the body. It hydrolyses the 1,4-linkage in the carbohydrates to form blood-absorbable monosaccharides that ultimately increase ...
Imran Ahmad Khan, Furqan Ahmad Saddique, Sana Aslam, Usman Ali Ashfaq, Matloob Ahmad, Sami A. Al-Hussain, Magdi E. A. Zaki   +6 more
doaj   +1 more source

Morpholines-(IV)

Zeitschrift für Naturforschung B, 1971
Cyclodehydrohalogenation-beta-Lactams-Morpholin-3-ones-H'-NMR Spectroscopy N-Aryl-N-chloroacetyl-2-chlorophenacylamines (2) give morpholinones 3, or beta-lactams 4, depending upon the N-aryl-substituent. N-Phenyl-N- (2,3-dibromo-3-phenylpropionyl) -4-nitrophenacylamine did not undergo base-catalysed cyclization but gave, instead, the α,β-
Riaz F. Abdulla, Alok N. Bannerji
openaire   +1 more source