Results 41 to 50 of about 27,629 (258)

2D-QSAR study of synthesized novel derivatives of 1,3,4- Oxadiazoles as anti-inflammatory activity

BLDE University Journal of Health Sciences, 2020
Oxadiazole is a five-membered heterocyclic compound containing oxygen and two nitrogen atoms at C-1, C-3 and C-4 positions respectively. These derivatives are synthesized by both conventional as well as microwave-assisted.
M Somashekhar, R B Kotnal
doaj   +1 more source

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

Advanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong, Dong Hyeon Kim, Yujin Lim, Yongseok Kwon, Sangkyu Lee, Han Yong Bae   +5 more
wiley   +1 more source

N-[4-(Morpholinodiazenyl)phenyl]acetamide

Acta Crystallographica Section E, 2009
The title compound, C12H16N4O2, is a member of a family of morpholine-substituted aromatic diazenes. Conjugation of the diazene group π-system and the lone pair of electrons of the morpholine N atom is evidenced by a lengthened N=N double bond ...
Ralph Isovitsch, Frank R. Fronczek, Taylor Chin   +2 more
doaj   +1 more source

Syntheses and crystal structure of 4-[(pyridin-3-yl)diazenyl]morpholine and 1-[(pyridin-3-yl)diazenyl]-1,2,3,4-tetrahydroquinoline

Acta Crystallographica Section E: Crystallographic Communications, 2023
Two new heterocyclic 1,2,3-triazenes were synthesized by diazotation of 3-aminopyridine following respectively by coupling with morpholine or 1,2,3,4-tetrahydroquinoline.
Seynabou Sokhna, Insa Seck, Ibrahima El Hadj Thiam, Marc Presset, Samba Fama Ndoye, Lalla Aïcha Ba, Issa Samb, Simon Coles, James Orton, Matar Seck, Erwan Le Gall, Mohamed Gaye   +11 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

A paracetamol–morpholine adduct

Acta Crystallographica Section E Structure Reports Online, 2002
Paracetamol [also known as acet­amino­phen or N-(4-hydroxy­phenyl)­acet­amide] is an important analgesic drug that has recently been cocrystallized with a series of cyclic N- and O-donor compounds. This paper describes the formation of a paracetamol adduct with morpholine, viz. paracetamol–morpholine (1/2.5), C8H9NO2·2.5C4H9NO.
Oswald, I D H, Motherwell, W D S, Parsons, S, Pulham, C R   +3 more
openaire   +3 more sources

A General Enzymatic Strategy for Site‐Specific Incorporation of Modified Genetic Building Blocks Into DNA

Advanced Science, EarlyView.
Eco‐friendly enzymatic synthesis of high‐fidelity, site‐specifically modified DNA using 3′‐blocked nucleotides for full synthetic control and next‐generation sequencing compatibility. ABSTRACT Methods for site‐specific incorporation of modified DNA building blocks remain limited.
Raveena Raveena, Bhavana Ramadas, Sidney Becker   +2 more
wiley   +1 more source

Design, synthesis, in silico studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine

Frontiers in Chemistry
IntroductionCancer is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. These cells can invade nearby tissues and organs, or they may metastasize to other parts of the body through the ...
Elaheh Ataollahi, Leila Emami, Al-Anood Mohammad Al-Dies, Fateme Zare, Alireza Poustforoosh, Mina Emami, Fateme Saadat, Fateme Motamen, Zahra Rezaei, Soghra Khabnadideh, Soghra Khabnadideh   +10 more
doaj   +1 more source

Chronic morpholine exposure of rats

Fundamental and Applied Toxicology, 1989
The chronic toxicity and carcinogenic potential of morpholine were evaluated in 60 Sprague-Dawley rats/sex/group receiving morpholine at mean inhalation exposure concentrations of 0, 10, 50 and 150 ppm for 6 hr/day, 5 days/week, for 104 weeks. Survival, body weight gains, organ weights, hematology, and clinical chemistries were normal in exposed groups
Center for Environmental Toxicology, University of Florida, Alachua, Florida 32615 USA ( host institution ), Harbison, Raymond D., Marino, Dale J., Conaway, C.Clifford, Rubin, Lionel F., Gandy, Jay   +5 more
openaire   +3 more sources

Ammonium Salts of 5-(3-Chromenyl)-5H-chromeno[2,3-b]pyridines

Molbank, 2021
The ammonium salts of many drugs have significantly improved the solubility and, accordingly, the bioavailability of medicinal substances in the human body.
Yuliya E. Ryzhkova, Artem N. Fakhrutdinov, Michail N. Elinson   +2 more
doaj   +1 more source