Results 51 to 60 of about 24,393 (218)

2-Deoxystreptamine Conjugates by Truncation–Derivatization of Neomycin

Pharmaceuticals, 2010
A small library of truncated neomycin-conjugates is prepared by consecutive removal of 2,6-diaminoglucose rings, oxidation-reductive amination of ribose, oxidation-conjugation of aminopyridine/aminoquinoline and finally dimerization.
Floris L. van Delft, Floris P.J.T. Rutjes, Gerard W. Canters, Alessio Andreoni, Leandro C. Tabares, M. Waqar Aslam   +5 more
doaj   +1 more source

Catalytic Sulfur‐Atom Transfer Enabled by a Bis(disulfide) Titanium Complex

Angewandte Chemie International Edition, EarlyView.
Multi‐electron transformations with titanium are underexplored due to limited access to low‐valent precursors. The four‐electron activation of elemental sulfur by a Ti(IV) complex yields a rare titanium bis(disulfide) complex, enabling the efficient catalytic synthesis of isothiocyanates from isonitriles under mild conditions.
Sebastian Samir Cremer, Peter Coburger, Corinna Czernetzki, Gabriele Hierlmeier   +3 more
wiley   +1 more source

Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones

Molecules, 2013
New hetaryl- and alkylidenerhodanine derivatives 3a–d, 3e, and 4a–d were prepared from heterocyclic aldehydes 1a–d or acetaldehyde 1e. The treatment of several rhodanine derivatives 3a–d and 3e with piperidine or morpholine in THF under reflux, afforded (
Susana A. Zacchino, Justo Cobo, María Victoria Rodríguez, Manuel Nogueras, Rodrigo Abonia, Jairo Quiroga, Carlos Echeverry, Marcela Raimondi, Juan Ramírez, Alberto Insuasty, Braulio Insuasty   +10 more
doaj   +1 more source

Morpholine, Piperazine, and Piperidine Derivatives as Antidiabetic Agents

Molecules
Diabetes mellitus is a severe endocrine disease that affects more and more people every year. Modern medical chemistry sets itself the task of finding effective and safe drugs against diabetes.
Darya Zolotareva, Alexey Zazybin, Anuar Dauletbakov, Yelizaveta Belyankova, Beatriz Giner Parache, Saniya Tursynbek, Tulegen Seilkhanov, Anel Kairullinova   +7 more
doaj   +1 more source

Morpholines — (II)

Zeitschrift für Naturforschung B, 1970
The new route to the synthesis of 3-oxo-1,4-oxazines 1 has been extended. N-aryl-N-chloroacetyl-m-nitro-phenacyl amines afford either only oxazine, or beta-lactam or both depending on the nature of the N-aryl substituent. A set of rules indicates from which precursors beta-lactam, as against morpholine formation, may be expected.
Basanta G. Chatterjee, S. K. Lahiri, Riaz F. Abdulla   +2 more
openaire   +1 more source

Synthesis and Preliminary Biological Evaluation of 1,3,5-Triazine Amino Acid Derivatives to Study Their MAO Inhibitors

Molecules, 2015
Three series of 4,6-dimethoxy-, 4,6-dipiperidino- and 4,6-dimorpholino-1,3,5-triazin-2-yl) amino acid derivatives were synthesized and characterized. A preliminary study for their monoamine oxidase inhibitory activity showed that compounds 7, 18, and 25 ...
Sherine N. Khattab, Hosam H. Khalil, Adnan A. Bekhit, Mohamed Mokbel Abd El-Rahman, Ayman El-Faham, Fernando Albericio   +5 more
doaj   +1 more source

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

Angewandte Chemie International Edition, EarlyView.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner, Agnes Bergmann, Chenxi Liu, Mira Behnam, Christian Klein, Franziska Thomas   +5 more
wiley   +1 more source

Influence of Morpholine Substitution on DNBS-Based 1,8-Naphthalimide Fluorescent Probes for H₂S Detection

Chemistry
A series of morpholine-appended 1,8-naphthalimide probes (S1–S5) was developed to investigate the influence of the morpholine moiety on H2S detection.
Trevor Dvorak, Sara Fox-Belmonte, Noah Burbul, Haishi Cao   +3 more
doaj   +1 more source

Synthesis of Thiazole Derivatives as Antimicrobial Agents by Green Chemistry Techniques

Journal of the Turkish Chemical Society, Section A: Chemistry, 2018
Amine (2) and (26) was obtained from the condensation of the corresponding amines with 3,4-difluoronitrobenzene. The reduction of nitro group produced the corresponding amines (3 and 27).
Serpil Demirci
doaj   +1 more source

Nicotinyl morpholine

Journal and proceedings of the Royal Society of New South Wales, 1937
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Harradence, Rita Harriet, Lions, Francis
openaire   +1 more source