Results 31 to 40 of about 45,031 (289)

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]

, 2014
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Anandan C., Arbes S. J., Asokananthan N., Billson J., Boyd M. J., Brown A., Brown A. D., Chan W. C., Chen J. C., Clive Robinson, Comoy E. E., David R. Garrod, Fattouh R., Gary K. Newton, Gelber L. E., Gough L., Jahnsen F. L., Jie Chen, Jihui Zhang, Jonathan P. Richardson, Kerry Jenkins, King C., Liu H., Marcaccini S., Mark R. Stewart, Meriel R. Major, Milan D. S., Moffatt M. F., Möller G. M., Nicola J. Francis-Newton, Peat J. K., Peat J. K., Pei Lai, Pichavant M., Platts-Mills T. A., Platts-Mills T. A., Platts-Mills T. A. E., Platts-Mills T. A. E., Prefontaine D., Purello-D’Ambrosia F., Rebekah E. Key, Robinson C., Silvestri M., Smith J. M., Sporik R., Squillace S. P., Steven M. Lloyd, Stewart G. A., Stuart Firth-Clark, Takai T., Trevor R. Perrior, Wan H., Ying S., Zhang J., Zhang J., Zhang J., Zhang J.   +56 more
core   +10 more sources

Development of a Method for Rapid Determination of Morpholine in Juices and Drugs by Gas Chromatography-Mass Spectrometry

Journal of Analytical Methods in Chemistry, 2018
A reliable derivatization method has been developed to detect and quantify morpholine in apple juices and ibuprofen with gas chromatography-mass spectrometry.
Mengsi Cao, Pingping Zhang, Yanru Feng, Huayin Zhang, Huaijiao Zhu, Kaoqi Lian, Weijun Kang   +6 more
doaj   +1 more source

Optimization of diarylazines as anti-HIV agents with dramatically [PDF]

, 2013
Non-nucleoside inhibitors of HIV-1 reverse transcriptase are reported that have ca. 100-fold greater solubility than the structurally related drugs etravirine and rilpivirine, while retaining high anti-viral activity.
Anderson, Karen S., Bollini, Mariela, Cisneros, José A., Jorgensen, William L., Spasov, Krasimir A.   +4 more
core   +1 more source

Hexa-μ2-chlorido-μ4-oxido-tetrakis[(morpholine-κN)copper(II)] methanol disolvate

Acta Crystallographica Section E, 2014
In the title solvate, [Cu4(μ2-Cl)6(μ4-O)(C4H9NO)4]·2CH3OH, each Cu2+ ion in the tetranuclear complex has a trigonal–bipyramidal coordination arising from three bridging chloride ions in equatorial positions and the central μ4-O2− ion and morpholine N ...
Kateryna Gubina, Vladimir Ovchynnikov, Vladimir Amirkhanov   +2 more
doaj   +1 more source

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, EarlyView.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

The anodic oxidation of bases in the solvent m-cresol [PDF]

, 1974
The oxidation of bases in the solvent m-cresol was investigated by polarography, voltammetry at the rotating platinum disc electrode and by chronopotentiometry. It was shown that the m-cresolate ion is the electroactive species in this reaction.
Bos, M., Dahmen, E.A.M.F.
core   +2 more sources

Synthesis of Certain New Morpholine Derivatives Bearing a Thiazole Moiety

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019
Morpholineis a synthetic simple heterocyclic organic compound having characteristicfunctional groups of amine and ether. Feasible physicochemical properties(polarity and solubility), low cost and wide availability make it a suitablecandidate for the ...
Nurcan Berber
doaj   +1 more source

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis. [PDF]

, 2016
A long-standing challenge in synthetic chemistry is the development of the transamidation reaction. This process, which involves the conversion of one amide to another, is typically plagued by unfavourable kinetic and thermodynamic factors. Although some
Anthony, Sarah M, Baker, Emma L, Garg, Neil K, Yamano, Michael M, Zhou, Yujing   +4 more
core   +2 more sources

Synthesis of 3-Methyl-1-morpholin-4-ylmethyl-2,6-diphenylpiperidin-4-one

Molbank, 2009
This paper describes the synthesis of 3-methyl-1-morpholin-4-ylmethyl-2,6-diphenylpiperidin-4-one from 3-methyl-2,6-diphenylpiperidin-4-one. The synthesized compound was characterized by FT-IR, 1H NMR, EI-MS and elemental analysis.
Bathey R. Venkatraman, Samiappan Sathish Kumar, Helen P. Kavitha   +2 more
doaj   +1 more source

Seasonal variation of aliphatic amines in marine sub-micrometer particles at the Cape Verde islands [PDF]

, 2009
Monomethylamine (MA), dimethylamine (DMA) and diethylamine (DEA) were detected at non-negligible concentrations in sub-micrometer particles at the Cap Verde Atmospheric Observatory (CVAO) located on the island of São Vicente in Cape Verde during algal ...
Gnauk, T., Herrmann, H., Iinuma, Y., Karstensen, Johannes, Lehmann, S., Müller, C., van Pinxteren, D.   +6 more
core   +1 more source