Results 91 to 100 of about 23,743 (176)

Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal, Raphael Hitti, William D. Lubell   +2 more
wiley   +1 more source

Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák, Petr Vyvlečka, Ivan Nemec, An Matheeussen, Natascha Van Pelt, Paul Cos, Guy Caljon, Vladimír Kryštof, Lucie Brulíková   +8 more
wiley   +1 more source

An Imidazo[2,1‐b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α‐Hemolysin by Blocking the Pullout of Its Stem Domain

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
A high‐throughput cellular screen based on Ca2+ influx in U937 monocytic cells identified thiadiazoles as small‐molecule inhibitors of α‐hemolysin, a key virulence factor of Staphylococcus aureus. The thiadiazole 1 prevents pore formation by a dual mechanism that prevents stem loop unfolding as well as membrane attachment.
Vadim S. Korotkov, Peer Lukat, Raffaella Di Lucrezia, Aditya Shekhar, Carsten Degenhart, Randi Diestel, Ursula Bilitewski, Klaus Dinkel, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Quaternized Curcumin Derivative—Synthesis, Physicochemical Characteristics, and Photocytotoxicity, Including Antibacterial Activity after Irradiation with Blue Light

Molecules
Over the past few years, numerous bacterial strains have become resistant to selected drugs from various therapeutic groups. A potential tool in the fight against these strains is antimicrobial photodynamic therapy (APDT).
Pawel Bakun, Marcin Wysocki, Magdalena Stachowiak, Marika Musielak, Jolanta Dlugaszewska, Dariusz T. Mlynarczyk, Lukasz Sobotta, Wiktoria M. Suchorska, Tomasz Goslinski   +8 more
doaj   +1 more source

MORPHOLINE [PDF]

Chemical & Engineering News Archive, 1946
openaire   +1 more source

Morpholine

Hartwig, Andrea, MAK Commission, Arand, Michael   +2 more
  +4 more sources

MORPHOLINE [PDF]

Chemical & Engineering News Archive, 1953
openaire   +1 more source

Morpholine as a privileged scaffold for neurodegenerative disease therapeutics. [PDF]

RSC Adv
Parmbil SK, Kumar S, Rangarajan TM, Grace Thomas Parambi D, Maliyakkal N, Petzer A, Petzer JP, Mathew B.   +7 more
europepmc   +1 more source

The arginine/gallic acid-based deep eutectic solvent as a capable catalyst for the green synthesis of pyrano[2,3-d]pyrimidines. [PDF]

Sci Rep
Chegeni E, Habibi D, Monem A.
europepmc   +1 more source

Isostearamidopropyl Morpholine Lactate [PDF]

International Journal of Toxicology, 2017
openaire   +2 more sources